Fiche traitement
Ambulation Study in Multiple Sclerosis
Brown, Theodore R., M.D., MPH • SEP
Suivi actif
À vérifier
Résumé
Ambulation Study in Multiple Sclerosis est développé par Brown, Theodore R., M.D., MPH. Le traitement est actuellement en À vérifier. Il est associé à SEP. Son objectif thérapeutique principal est À vérifier. Le statut actuel est : suivi actif.
À vérifier
À vérifier
À vérifier
Brown, Theodore R., M.D., MPH
Non renseigné
This is a study comparing clinical tests of walking and balance. The goal of this study is to discover which of those tests are best at predicting walking problems due to MS.
2011-05-12
Début phase actuelle
Non disponible dans les sources synchronisées
Timeline clinique
À vérifier
Début phase actuelle
Non disponible dans les sources synchronisées
Préclinique
Phase 1
Phase 2
Phase 3
Approuvé
Objectif scientifique de l’étude
classification automatique vérifiable
À vérifier
Confiance automatique : 0%
Ce pourcentage n’est pas une probabilité de succès clinique.
Il mesure uniquement la force de la classification automatique de l’objectif scientifique. Le calcul part de 45 points, ajoute 7 points par unité de poids du mot-clé le plus fortement détecté, puis est plafonné à 95 %. Exemple : un score maximal de 2 donne 45 + (2 × 7) = 59 %.
Ce score est heuristique et doit être vérifié dans le protocole ou une publication.
Description affichée depuis l’essai compatible NCT00424359, afin d’éviter le mélange entre plusieurs indications d’une même molécule.
Contrôle de cohérence : 85/100
L’objectif est absent ou classé « Autre » et doit être recalculé à partir du protocole.
Transparence et qualité de la fiche
données vérifiablesClassificationÀ vérifier
Confiance de la fiche85 %
Source principaleSource officielle ou publication indexée
Dernière vérification2011-05-12
Anomalies détectées1
Validation humaineValidation humaine non effectuée
Donnée issue d’une source
Donnée normalisée automatiquement
Interprétation algorithmique
Classification scientifique multi-axes
ne pas confondre statut et résultatÉtat de l’étudeTerminée
Disponibilité des résultatsRésultats à vérifier
InterprétationImpossible à déterminer
Niveau de preuveNon évaluable
Un essai terminé n’est pas nécessairement positif. Un essai arrêté n’est classé comme échec scientifique que lorsqu’un résultat ou une raison explicite le confirme.
Indicateurs factuels
sans score subjectifPhase enregistréeÀ vérifier
Études associées1
Publications associées17
Statut consolidéSuivi actif
Aucune chance de succès, note d’innovation, potentiel thérapeutique ou probabilité de commercialisation n’est calculé tant qu’un modèle validé et des données suffisantes ne sont pas disponibles.
Historique factuel de la molécule
22 événement(s) daté(s)Cette liste reprend uniquement les dates trouvées dans les registres et publications liés. Elle ne constitue pas une prévision.
| Date | Événement | Source |
|---|---|---|
| 2005-04-01 | Début de l’étudeNCT00424359 | Registre d’essai clinique |
| 2009-01-01 | Fin de l’étude prévue / enregistréeNCT00424359 | Registre d’essai clinique |
| 2011-05-12 | Dernière mise à jour des donnéesAmbulation Study in Multiple Sclerosis | Biomedical Watch |
| 2026-07-08 | Création de l’enregistrementNCT00424359 | Registre d’essai clinique |
| 2026-07-08 | PublicationComparative effects of pilates-based interventions on functional mobility, balance, fatigue, and quality of life in people with multiple sclerosis: a systematic review and network meta-analysis. | BMC sports science, medicine & rehabilitation |
| 2026-07-08 | PublicationAssessing Progression Independent of Relapse Activity in Multiple Sclerosis Using a Patient-Reported Disability Measure and Self-Administered Neuroperformance Outcomes. | Annals of neurology |
| 2026-07-10 | PublicationAssociation of epiretinal membranes with disability in people with multiple sclerosis. | Multiple sclerosis (Houndmills, Basingstoke, England) |
| 2026-07-13 | Dernière mise à jour du registreNCT00424359 | Registre d’essai clinique |
| 2026-07-14 | PublicationEfficacy and safety of amantadine in the treatment of fatigue in multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials. | Journal of neural transmission (Vienna, Austria : 1996) |
| 2026-07-14 | PublicationInvestigating the treatment of vascular risk with simvastatin in secondary progressive multiple sclerosis: analysis from the MS-STAT2 randomized controlled trial. | Brain communications |
| 2026-07-18 | PublicationEfficacy and Safety of Intermittent Negative Pressure Treatment on Spasticity and Spasticity-Related Symptoms in Patients with Multiple Sclerosis: A Two-Arm Randomized Trial. | Neurology and therapy |
| 2026-07-18 | PublicationIndividually designed fall prevention strategies compared to generic strategies for mastering complex fall risk situations in people with multiple sclerosis: study protocol of a randomised controlled trial. | BMJ open |
| 2026-07-22 | PublicationClinical and cost-effectiveness of the iStep-MS physical activity and sedentary behaviour intervention for managing fatigue in people with multiple sclerosis: protocol for a m randomised controlled trial. | BMJ open |
| 2026-07-23 | PublicationPotential benefits of music-based therapies on rehabilitation outcomes in people with multiple sclerosis: a systematic review. | BMJ open |
| 2026-07-29 | PublicationArtificial Intelligence Applications to Support Physical Activity, Mobility, and Fatigue Management in People with Multiple Sclerosis: A Scoping Review. | Healthcare (Basel, Switzerland) |
| 2026-07-29 | PublicationFeasibility of Privacy-Preserving LiDAR-Based Continuous Gait and Activity Monitoring in Three People with Multiple Sclerosis: A Technical Proof-of-Concept Case Study. | Sensors (Basel, Switzerland) |
| 2026-08-08 | PublicationConstruct validation of multiple sclerosis walking scale-12 scores among black individuals with multiple sclerosis: preliminary evidence. | Multiple sclerosis and related disorders |
| 2026-08-08 | PublicationVascular risk factors' impact on motor performance and sensorimotor network structural integrity in multiple sclerosis. | Multiple sclerosis (Houndmills, Basingstoke, England) |
| 2026-08-13 | PublicationEffect of external versus internal focus of attention instructions on gait performance in people with multiple sclerosis. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology |
| 2026-08-13 | PublicationClinicians' and patients' perspectives of a mobility technician role in the hospital to promote ambulation: A qualitative study. | Journal of hospital medicine |
| 2026-08-16 | PublicationTherapeutic potential of astrocyte transdifferentiated neurons. | Neural regeneration research |
| 2026-08-16 | PublicationFrom options to decisions: an innovative model for treatment sequencing in relapsing-remitting multiple sclerosis. | Journal of medical economics |
Début phase actuelle
Non disponible dans les sources synchronisées
Essais cliniques liés
1 essai(s)
Début phase actuelle
Non disponible dans les sources synchronisées
| NCT | Titre | Phase | Statut administratif | Pays | Sponsor |
|---|---|---|---|---|---|
| NCT00424359 | Ambulation Study in Multiple Sclerosis | À vérifier | COMPLETED | Non communiqué | Brown, Theodore R., M.D., MPH |
Publications liées
17 publication(s)Publications liées
17 publication(s)| Titre | PMID | DOI | Journal | Date |
|---|---|---|---|---|
| Therapeutic potential of astrocyte transdifferentiated neurons. Voir source | 41467429 | 10.4103/NRR.NRR-D-25-00554 | Neural regeneration research | |
| From options to decisions: an innovative model for treatment sequencing in relapsing-remitting multiple sclerosis. Voir source | 42339705 | 10.1080/13696998.2026.2688699 | Journal of medical economics | |
| Effect of external versus internal focus of attention instructions on gait performance in people with multiple sclerosis. Voir source | 42584733 | 10.1007/s10072-026-09315-7 | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology | |
| Clinicians' and patients' perspectives of a mobility technician role in the hospital to promote ambulation: A qualitative study. Voir source | 42591059 | 10.1002/jhm.70423 | Journal of hospital medicine | |
| Construct validation of multiple sclerosis walking scale-12 scores among black individuals with multiple sclerosis: preliminary evidence. Voir source | 42561745 | 10.1016/j.msard.2026.107422 | Multiple sclerosis and related disorders | |
| Vascular risk factors' impact on motor performance and sensorimotor network structural integrity in multiple sclerosis. Voir source | 42562771 | 10.1177/13524585261464469 | Multiple sclerosis (Houndmills, Basingstoke, England) | |
| Artificial Intelligence Applications to Support Physical Activity, Mobility, and Fatigue Management in People with Multiple Sclerosis: A Scoping Review. Voir source | 42512735 | 10.3390/healthcare14142219 | Healthcare (Basel, Switzerland) | |
| Feasibility of Privacy-Preserving LiDAR-Based Continuous Gait and Activity Monitoring in Three People with Multiple Sclerosis: A Technical Proof-of-Concept Case Study. Voir source | 42515339 | 10.3390/s26144455 | Sensors (Basel, Switzerland) | |
| Potential benefits of music-based therapies on rehabilitation outcomes in people with multiple sclerosis: a systematic review. Voir source | 42486519 | 10.1136/bmjopen-2026-116420 | BMJ open | |
| Clinical and cost-effectiveness of the iStep-MS physical activity and sedentary behaviour intervention for managing fatigue in people with multiple sclerosis: protocol for a m randomised controlled trial. Voir source | 42476739 | 10.1136/bmjopen-2026-121358 | BMJ open | |
| Efficacy and Safety of Intermittent Negative Pressure Treatment on Spasticity and Spasticity-Related Symptoms in Patients with Multiple Sclerosis: A Two-Arm Randomized Trial. Voir source | 42455218 | 10.1007/s40120-026-00985-1 | Neurology and therapy | |
| Individually designed fall prevention strategies compared to generic strategies for mastering complex fall risk situations in people with multiple sclerosis: study protocol of a randomised controlled trial. Voir source | 42457429 | 10.1136/bmjopen-2025-115430 | BMJ open | |
| Efficacy and safety of amantadine in the treatment of fatigue in multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials. Voir source | 42439933 | 10.1007/s00702-026-03213-0 | Journal of neural transmission (Vienna, Austria : 1996) | |
| Investigating the treatment of vascular risk with simvastatin in secondary progressive multiple sclerosis: analysis from the MS-STAT2 randomized controlled trial. Voir source | 42440661 | 10.1093/braincomms/fcag240 | Brain communications | |
| Association of epiretinal membranes with disability in people with multiple sclerosis. Voir source | 42405525 | 10.1177/13524585261446834 | Multiple sclerosis (Houndmills, Basingstoke, England) | |
| Comparative effects of pilates-based interventions on functional mobility, balance, fatigue, and quality of life in people with multiple sclerosis: a systematic review and network meta-analysis. Voir source | 42400084 | 10.1186/s13102-026-01827-1 | BMC sports science, medicine & rehabilitation | |
| Assessing Progression Independent of Relapse Activity in Multiple Sclerosis Using a Patient-Reported Disability Measure and Self-Administered Neuroperformance Outcomes. Voir source | 42405485 | 10.1002/ana.78275 | Annals of neurology |
Sources officielles
liens de rechercheDernière mise à jour des données : 2011-05-12
Ces sources sont proposées pour vérification. Les informations de la fiche doivent être confirmées dans les registres officiels ou les publications originales.