Fiche traitement
Ginseng
Isfahan University of Medical Sciences • SEP
Suivi actif
Phase 2
Résumé
Ginseng est développé par Isfahan University of Medical Sciences. Le traitement est actuellement en Phase 2. Il est associé à SEP. Son objectif thérapeutique principal est Traitement symptomatique. Le statut actuel est : suivi actif.
À vérifier
Traitement symptomatique
Phase 2
Isfahan University of Medical Sciences
Iran
The purpose of this study was to evaluate the efficacy and safety of Ginseng in treatment of fatigue and Quality of Life of MS patients.
2012-10-22
Début phase actuelle
Non disponible dans les sources synchronisées
Timeline clinique
Phase 2
Début phase actuelle
Non disponible dans les sources synchronisées
Préclinique
Phase 1
Phase 2
Phase 3
Approuvé
Objectif scientifique de l’étude
classification automatique vérifiable
Traitement symptomatique
Confiance automatique : 87%
Ce pourcentage n’est pas une probabilité de succès clinique.
Il mesure uniquement la force de la classification automatique de l’objectif scientifique. Le calcul part de 45 points, ajoute 7 points par unité de poids du mot-clé le plus fortement détecté, puis est plafonné à 95 %. Exemple : un score maximal de 2 donne 45 + (2 × 7) = 59 %.
Indices détectés : fatigue → Traitement symptomatique, symptom → Traitement symptomatique
Ce score est heuristique et doit être vérifié dans le protocole ou une publication.
Description affichée depuis l’essai compatible NCT01712373, afin d’éviter le mélange entre plusieurs indications d’une même molécule.
Aucune incohérence majeure détectée entre la maladie, l’objectif et la description.
Transparence et qualité de la fiche
données vérifiablesClassificationCohérente automatiquement
Confiance de la fiche100 %
Source principaleSource officielle ou publication indexée
Dernière vérification2012-10-22
Anomalies détectées0
Validation humaineValidation humaine non effectuée
Donnée issue d’une source
Donnée normalisée automatiquement
Interprétation algorithmique
Classification scientifique multi-axes
ne pas confondre statut et résultatÉtat de l’étudeTerminée
Disponibilité des résultatsRésultats à vérifier
InterprétationImpossible à déterminer
Niveau de preuveNon évaluable
Un essai terminé n’est pas nécessairement positif. Un essai arrêté n’est classé comme échec scientifique que lorsqu’un résultat ou une raison explicite le confirme.
Indicateurs factuels
sans score subjectifPhase enregistréePhase 2
Études associées1
Publications associées20
Statut consolidéSuivi actif
Aucune chance de succès, note d’innovation, potentiel thérapeutique ou probabilité de commercialisation n’est calculé tant qu’un modèle validé et des données suffisantes ne sont pas disponibles.
Historique factuel de la molécule
25 événement(s) daté(s)Cette liste reprend uniquement les dates trouvées dans les registres et publications liés. Elle ne constitue pas une prévision.
| Date | Événement | Source |
|---|---|---|
| 2010-12-01 | Début de l’étudeNCT01712373 | Registre d’essai clinique |
| 2011-04-01 | Fin de l’étude prévue / enregistréeNCT01712373 | Registre d’essai clinique |
| 2012-10-22 | Dernière mise à jour des donnéesGinseng | Biomedical Watch |
| 2026-07-08 | Création de l’enregistrementNCT01712373 | Registre d’essai clinique |
| 2026-07-08 | PublicationInhibition, biochemical activities, and control efficacy of fluopyram·tebuconazole against spp. causing GALSB: Implications for QoI fungicide resistance management. | Plant disease |
| 2026-07-08 | PublicationGinsenoside Rg1 attenuates platelet activation under shear stress via multi-target suppression of PI3K/AKT and ERK1/2 pathways: an in vitro microfluidic study. | Journal of thrombosis and thrombolysis |
| 2026-07-08 | PublicationProcyanidin B2 alleviates triphenyl phosphate-induced colon injury through Tmigd1/NF-κB/NLRP3 signal axis. | Ecotoxicology and environmental safety |
| 2026-07-08 | PublicationGinseng glycopeptides from Panax ginseng: Process optimization, structural characteristics, and immunomodulatory activities. | International journal of biological macromolecules |
| 2026-07-10 | PublicationThe Convergence of Ancient Medical Wisdom and Modern Physiology: Sodium Ion Wave Propagation in Endothelial Cells, IL-1 Vascular Pathways, and the Six-Day Progression Pattern of Clinical Symptoms. | Advances in experimental medicine and biology |
| 2026-07-10 | PublicationPreparation, characterization, and preventive effects of ginseng polysaccharide-stabilized selenium nanoparticles against DSS-induced colitis. | Nanomedicine (London, England) |
| 2026-07-12 | PublicationAerobic conditioning and ginsenoside modulation modify molecular resilience in middle-aged rats: Differential effects of individual and combined interventions. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie |
| 2026-07-12 | PublicationGinseng marc-derived low-molecular-weight neutral glucan SN-GOS ameliorates ulcerative colitis via inhibition of apoptosis and activation of autophagy in human intestinal HT-29 cells and DSS-induced inflammatory colitis mice. | Carbohydrate research |
| 2026-07-13 | Dernière mise à jour du registreNCT01712373 | Registre d’essai clinique |
| 2026-07-14 | PublicationGinsenoside Rg3 in Cancer Therapy: Pharmacokinetics, Molecular Mechanisms, and Synergistic Combinations. | The American journal of Chinese medicine |
| 2026-07-22 | PublicationIdentification of (20R)-protopanaxadiol from Panax ginseng as a novel anti-SARS-CoV-2 compound. | FEBS open bio |
| 2026-07-22 | PublicationMetabolic engineering of tobacco for heterologous production of rare ginsenosides CK and Rh2. | Frontiers in plant science |
| 2026-07-23 | PublicationZnGeO:Mn Luminescent Superparticles/Au-Ag Bimetallic Nanoarrays for ECL Detection of miRNA-156a in Ginseng Exosomes. | Analytical chemistry |
| 2026-07-23 | Publication[Natural bear bile powder attenuates lipopolysaccharide-induced acute lung injury in mice by regulating the NF-κB and Nrf-2/HO-1 signaling pathways]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University |
| 2026-08-08 | PublicationThe effects of grafting on the stems of were jointly analyzed by transcriptomics and metabolomics. | Frontiers in plant science |
| 2026-08-08 | PublicationSeasonal precipitation and soil mineral nutrients contribute to variation in ginsenoside accumulation in American ginseng across China's major production regions. | Frontiers in plant science |
| 2026-08-13 | PublicationInterfacial and Molecular Mechanisms of Pancreatic Lipase Modulation by Saponin-Rich Extracts with Antioxidant Activity. | Molecules (Basel, Switzerland) |
| 2026-08-13 | PublicationComprehensive Genome Identification of the Gene Family in and Expression Analysis of Genes in Response to MeJA. | Biology |
| 2026-08-16 | PublicationUHPLC/Q-TOF-MS-based blood-component profiling and multi-omics analysis reveal potential protective mechanisms of Shenzhuo Formula against diabetic kidney disease. | Journal of pharmaceutical and biomedical analysis |
| 2026-08-16 | PublicationDeciphering the PgLEA2-50 interactome: implications for abiotic stress responses in . | Plant signaling & behavior |
| 2026-08-16 | PublicationIntegrating multi-omics and network pharmacology in a systems approach: a mechanism study of ginseng-derived panaxadiol saponins against immune-mediated aplastic anemia. | Journal of ethnopharmacology |
Début phase actuelle
Non disponible dans les sources synchronisées
Essais cliniques liés
1 essai(s)
Début phase actuelle
Non disponible dans les sources synchronisées
| NCT | Titre | Phase | Statut administratif | Pays | Sponsor |
|---|---|---|---|---|---|
| NCT01712373 | Ginseng in Treatment of Fatigue in Multiple Sclerosis | Phase 2 | COMPLETED | Iran | Isfahan University of Medical Sciences |
Publications liées
20 publication(s)Publications liées
20 publication(s)| Titre | PMID | DOI | Journal | Date |
|---|---|---|---|---|
| UHPLC/Q-TOF-MS-based blood-component profiling and multi-omics analysis reveal potential protective mechanisms of Shenzhuo Formula against diabetic kidney disease. Voir source | 42385329 | 10.1016/j.jpba.2026.117616 | Journal of pharmaceutical and biomedical analysis | |
| Deciphering the PgLEA2-50 interactome: implications for abiotic stress responses in . Voir source | 41645041 | 10.1080/15592324.2026.2624961 | Plant signaling & behavior | |
| Integrating multi-omics and network pharmacology in a systems approach: a mechanism study of ginseng-derived panaxadiol saponins against immune-mediated aplastic anemia. Voir source | 42497599 | 10.1016/j.jep.2026.122216 | Journal of ethnopharmacology | |
| Interfacial and Molecular Mechanisms of Pancreatic Lipase Modulation by Saponin-Rich Extracts with Antioxidant Activity. Voir source | 42588448 | 10.3390/molecules31152600 | Molecules (Basel, Switzerland) | |
| Comprehensive Genome Identification of the Gene Family in and Expression Analysis of Genes in Response to MeJA. Voir source | 42589118 | 10.3390/biology15151251 | Biology | |
| The effects of grafting on the stems of were jointly analyzed by transcriptomics and metabolomics. Voir source | 42558319 | 10.3389/fpls.2026.1824273 | Frontiers in plant science | |
| Seasonal precipitation and soil mineral nutrients contribute to variation in ginsenoside accumulation in American ginseng across China's major production regions. Voir source | 42558931 | 10.3389/fpls.2026.1901947 | Frontiers in plant science | |
| ZnGeO:Mn Luminescent Superparticles/Au-Ag Bimetallic Nanoarrays for ECL Detection of miRNA-156a in Ginseng Exosomes. Voir source | 42485233 | 10.1021/acs.analchem.6c03825 | Analytical chemistry | |
| [Natural bear bile powder attenuates lipopolysaccharide-induced acute lung injury in mice by regulating the NF-κB and Nrf-2/HO-1 signaling pathways]. Voir source | 42486831 | 10.12122/j.issn.1673-4254.2026.07.16 | Nan fang yi ke da xue xue bao = Journal of Southern Medical University | |
| Identification of (20R)-protopanaxadiol from Panax ginseng as a novel anti-SARS-CoV-2 compound. Voir source | 42482536 | 10.1002/2211-5463.70307 | FEBS open bio | |
| Metabolic engineering of tobacco for heterologous production of rare ginsenosides CK and Rh2. Voir source | 42483519 | 10.3389/fpls.2026.1884201 | Frontiers in plant science | |
| Ginsenoside Rg3 in Cancer Therapy: Pharmacokinetics, Molecular Mechanisms, and Synergistic Combinations. Voir source | 42438288 | 10.1142/S0192415X26500552 | The American journal of Chinese medicine | |
| Aerobic conditioning and ginsenoside modulation modify molecular resilience in middle-aged rats: Differential effects of individual and combined interventions. Voir source | 42435534 | 10.1016/j.biopha.2026.119758 | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie | |
| Ginseng marc-derived low-molecular-weight neutral glucan SN-GOS ameliorates ulcerative colitis via inhibition of apoptosis and activation of autophagy in human intestinal HT-29 cells and DSS-induced inflammatory colitis mice. Voir source | 42435659 | 10.1016/j.carres.2026.110040 | Carbohydrate research | |
| The Convergence of Ancient Medical Wisdom and Modern Physiology: Sodium Ion Wave Propagation in Endothelial Cells, IL-1 Vascular Pathways, and the Six-Day Progression Pattern of Clinical Symptoms. Voir source | 42420720 | 10.1007/978-3-032-22285-5_20 | Advances in experimental medicine and biology | |
| Preparation, characterization, and preventive effects of ginseng polysaccharide-stabilized selenium nanoparticles against DSS-induced colitis. Voir source | 42423036 | 10.1080/17435889.2026.2697806 | Nanomedicine (London, England) | |
| Inhibition, biochemical activities, and control efficacy of fluopyram·tebuconazole against spp. causing GALSB: Implications for QoI fungicide resistance management. Voir source | 42417719 | 10.1094/PDIS-12-25-2523-RE | Plant disease | |
| Ginsenoside Rg1 attenuates platelet activation under shear stress via multi-target suppression of PI3K/AKT and ERK1/2 pathways: an in vitro microfluidic study. Voir source | 42418135 | 10.1007/s11239-026-03355-8 | Journal of thrombosis and thrombolysis | |
| Procyanidin B2 alleviates triphenyl phosphate-induced colon injury through Tmigd1/NF-κB/NLRP3 signal axis. Voir source | 42413335 | 10.1016/j.ecoenv.2026.120482 | Ecotoxicology and environmental safety | |
| Ginseng glycopeptides from Panax ginseng: Process optimization, structural characteristics, and immunomodulatory activities. Voir source | 42413671 | 10.1016/j.ijbiomac.2026.153382 | International journal of biological macromolecules |
Sources officielles
liens de rechercheDernière mise à jour des données : 2012-10-22
Ces sources sont proposées pour vérification. Les informations de la fiche doivent être confirmées dans les registres officiels ou les publications originales.