Fiche traitement
tDCS
IRCCS San Raffaele • Parkinson
Suivi actif
Non applicable
Résumé
tDCS est développé par IRCCS San Raffaele. Le traitement est actuellement en Non applicable. Il est associé à Parkinson. Son objectif thérapeutique principal est À vérifier. Le statut actuel est : suivi actif.
À vérifier
À vérifier
Non applicable
IRCCS San Raffaele
Italy
The trial will include 51 adult participants with Parkinson's disease and postural instability and gait disorders (PD-PIGD) and 20 age- and sex-matched healthy controls.
At baseline (T0) patients will undergo neurological and cognitive/behavioural assessments, gait/balance evaluation, neuroimaging/neurophysiology assessments including brain magnetic resonance imaging (MRI), functional Near Infrared Spectroscopy (fNIRS) and Electroencephalography (EEG) acquisitions to assess brain activity, connectivity and structural changes, and blood sample.
PD-PIGD patients will be randomly allocated in two training groups: the REHAB+SHAM group and the REHAB + STIM group.
The REHAB+SHAM group will perform 2 cycles of dual-task gait/balance training consisting of action observation training (AOT) and motor imagery (MI) combined with practicing the observed-imagined exercises (an approach that has been demonstrated to be effective to improve gait and mobility in PD-PIGD), additionally they will undergo SHAM transcranial and trans-spinal stimulation. SHAM stimulation will be performed using the same montage used for transcranial and spinal stimulation (explained below), however an initial current is delivered and programmed to fade off in a brief period of time.
The REHAB + STIM group will perform the same exercises combined with non-invasive stimulation.
Non-invasive stimulation will be administered using tDCS with trans-spinal Direct Current Stimulation (tsDCS) or transcranial Direct Current Stimulation (tDCS) alone combined with SHAMtsDCS.
This design will aid in determining not only whether non-invasive stimulation can enhance rehabilitation outcomes but also whether the combination of tDCS and tsDCS could lead to improved results compared to tDCS alone.
The motor-cognitive training of the REHAB+SHAM group will consist of 2 cycles of SHAM stimulation and training lasting 6 weeks, 3 times per week, about 1 hour each session, separated by a 8-week washout period.
The REHAB + STIM group will undergo 2 cycles of the 6-week training, separated by a 8-week washout period with a cross-over design: half of subjects will first receive 6-week training with tDCS+SHAMtsDCS followed by 6-week tDCS+ tsDCS, while the other half will follow the reverse order, according to a randomization procedure.
After the training (i.e., 6-week visit \[W6\] and 20-week visit \[W20\]), PD-PIGD patients will be re-evaluated through neurological, cognitive/behavioural, gait/balance, neuroimaging/neurophysiology assessments and blood sample.
These measures (except for MRI at 14-week \[W14\] visit) will be also repeated at W14 and 28-week follow-up visits to assess maintenance of results.
20 healthy controls will also be recruited and evaluated at baseline. They will undergo the same assessments administered to PD-PIGD patients at T0 (neurological, cognitive/behavioural assessments, gait/balance evaluation using gait analysis systems, neuroimaging/neurophysiology, blood sample).
2025-11-25
Début phase actuelle
Non disponible dans les sources synchronisées
Timeline clinique
Non applicable
Début phase actuelle
Non disponible dans les sources synchronisées
Préclinique
Phase 1
Phase 2
Phase 3
Approuvé
Objectif scientifique de l’étude
classification automatique vérifiable
À vérifier
Confiance automatique : 0%
Ce pourcentage n’est pas une probabilité de succès clinique.
Il mesure uniquement la force de la classification automatique de l’objectif scientifique. Le calcul part de 45 points, ajoute 7 points par unité de poids du mot-clé le plus fortement détecté, puis est plafonné à 95 %. Exemple : un score maximal de 2 donne 45 + (2 × 7) = 59 %.
Ce score est heuristique et doit être vérifié dans le protocole ou une publication.
Description affichée depuis l’essai compatible NCT06868160, afin d’éviter le mélange entre plusieurs indications d’une même molécule.
Contrôle de cohérence : 85/100
L’objectif est absent ou classé « Autre » et doit être recalculé à partir du protocole.
Transparence et qualité de la fiche
données vérifiablesClassificationÀ vérifier
Confiance de la fiche85 %
Source principaleSource officielle ou publication indexée
Dernière vérification2025-11-25
Anomalies détectées1
Validation humaineValidation humaine non effectuée
Donnée issue d’une source
Donnée normalisée automatiquement
Interprétation algorithmique
Classification scientifique multi-axes
ne pas confondre statut et résultatÉtat de l’étudeRecrutement en cours
Disponibilité des résultatsRésultats à vérifier
InterprétationImpossible à déterminer
Niveau de preuveNon évaluable
Un essai terminé n’est pas nécessairement positif. Un essai arrêté n’est classé comme échec scientifique que lorsqu’un résultat ou une raison explicite le confirme.
Indicateurs factuels
sans score subjectifPhase enregistréeNon applicable
Études associées13
Publications associées59
Statut consolidéSuivi actif
Aucune chance de succès, note d’innovation, potentiel thérapeutique ou probabilité de commercialisation n’est calculé tant qu’un modèle validé et des données suffisantes ne sont pas disponibles.
Historique factuel de la molécule
102 événement(s) daté(s)Cette liste reprend uniquement les dates trouvées dans les registres et publications liés. Elle ne constitue pas une prévision.
| Date | Événement | Source |
|---|---|---|
| 2007-07-01 | Début de l’étudeNCT00521196 | Registre d’essai clinique |
| 2012-01-13 | Fin de l’étude prévue / enregistréeNCT00521196 | Registre d’essai clinique |
| 2013-11-01 | Début de l’étudeNCT02263274 | Registre d’essai clinique |
| 2014-09-01 | Début de l’étudeNCT02538094 | Registre d’essai clinique |
| 2015-01-01 | Début de l’étudeNCT02315781 | Registre d’essai clinique |
| 2016-10-01 | Début de l’étudeNCT03237754 | Registre d’essai clinique |
| 2017-12-06 | Fin de l’étude prévue / enregistréeNCT02315781 | Registre d’essai clinique |
| 2019-06-30 | Fin de l’étude prévue / enregistréeNCT02538094 | Registre d’essai clinique |
| 2020-05-30 | Fin de l’étude prévue / enregistréeNCT03237754 | Registre d’essai clinique |
| 2020-11-13 | Début de l’étudeNCT04606095 | Registre d’essai clinique |
| 2023-10-18 | Début de l’étudeNCT05958381 | Registre d’essai clinique |
| 2024-08-01 | Début de l’étudeNCT06554067 | Registre d’essai clinique |
| 2025-08-20 | Début de l’étudeNCT06816004 | Registre d’essai clinique |
| 2025-10-08 | Début de l’étudeNCT06868160 | Registre d’essai clinique |
| 2025-11-25 | Dernière mise à jour des donnéestDCS | Biomedical Watch |
| 2025-11-28 | Début de l’étudeNCT06719947 | Registre d’essai clinique |
| 2026-01-09 | Fin de l’étude prévue / enregistréeNCT02263274 | Registre d’essai clinique |
| 2026-04-15 | Début de l’étudeNCT07260253 | Registre d’essai clinique |
| 2026-07-08 | PublicationEfficacy of non-invasive brain stimulation in Alzheimer's disease: An umbrella review of meta-analyses. | Neuroscience and biobehavioral reviews |
| 2026-07-12 | Création de l’enregistrementNCT02315781 | Registre d’essai clinique |
| 2026-07-12 | Création de l’enregistrementNCT02538094 | Registre d’essai clinique |
| 2026-07-12 | PublicationEffects of transcranial direct current stimulation on Nicotine Use Disorder: A systematic review and meta-analysis. | Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco |
| 2026-07-12 | PublicationEfficacy of transcranial direct current stimulation for post-stroke urinary incontinence: study protocol for a randomized controlled trial. | Trials |
| 2026-07-12 | PublicationIntensive Rehabilitation With Adjunctive Bilateral Anodal tDCS in Post-Stroke Dysphagia: A Multicenter Randomized Controlled Trial. | European journal of neurology |
| 2026-07-12 | PublicationThe role of inferior frontal gyrus in emotion regulation: Evidence from fMRI and tDCS investigation. | International journal of psychophysiology : official journal of the International Organization of Psychophysiology |
| 2026-07-12 | PublicationEffects of transcranial electric stimulation on attentional functions in healthy adults: A meta-analysis. | Biological psychology |
| 2026-07-12 | PublicationConcurrent effects of EMG-triggered NMES and anodal tDCS on cortical and behavioural outcome measures: The role of ipsilateral versus contralateral anodal stimulation. | Brain research |
| 2026-07-13 | Dernière mise à jour du registreNCT02315781 | Registre d’essai clinique |
| 2026-07-13 | Dernière mise à jour du registreNCT02538094 | Registre d’essai clinique |
| 2026-07-14 | Création de l’enregistrementNCT02263274 | Registre d’essai clinique |
| 2026-07-14 | PublicationComparative Efficacy of Non-invasive Brain Stimulation for Pain, Anxiety, and Depression: A Systematic Review and Network Meta-analysis. | Pain and therapy |
| 2026-07-14 | PublicationEffect of transcranial direct current stimulation on psychomotor skill acquisition during laparoscopic training: a randomized controlled trial. | Surgical endoscopy |
| 2026-07-14 | PublicationDoes Anodal Transcranial Direct Current Stimulation Over the Primary Motor Cortex Really Enhance Motor Sequence Learning? | Biological psychiatry global open science |
| 2026-07-14 | PublicationSham tDCS controls: blinding, reliability, and a specification-grade checklist. | Frontiers in human neuroscience |
| 2026-07-18 | PublicationEffects of concurrent transcranial direct current stimulation on human motor skill learning: A systematic review and Bayesian meta-analysis. | Behavioural brain research |
| 2026-07-18 | PublicationTraining-induced cognitive coupling emerges under sham but not active transcranial electrical stimulation in older adults: a triple-blind, randomized, sham-controlled study. | Journal of neuroengineering and rehabilitation |
| 2026-07-18 | PublicationHeterogeneous Recruitment Curve Responses to Anodal Transcranial Direct Current Stimulation in Children With Unilateral Spastic Cerebral Palsy. | Neurorehabilitation and neural repair |
| 2026-07-22 | Création de l’enregistrementNCT00521196 | Registre d’essai clinique |
| 2026-07-22 | PublicationAdjunctive transcranial DC stimulation in the management of refractory drug-resistant focal epilepsy in POLG mitochondrial disease: A case series. | Seizure |
| 2026-07-22 | PublicationThe Additive Effects of Transcranial Direct Current Stimulation Combined With Exercise-Based Rehabilitation Interventions on Balance, Ankle Kinematics, and Muscle Activity in Individuals With Ankle Instability: A Systematic Review. | Health science reports |
| 2026-07-22 | PublicationPrefrontal transcranial direct current stimulation in alcohol use disorder: a pilot randomized sham-controlled trial with exploratory effects on reward craving and depressive symptoms. | Addictive behaviors |
| 2026-07-22 | PublicationIncreased brain glucose metabolism after anodal left DLPFC-right shoulder tDCS in ASD: an open-label pilot F-18 FDG PET/CT study. | BMC psychiatry |
| 2026-07-23 | PublicationComparative efficacy and safety of photobiomodulation, transcranial direct current stimulation, and repetitive transcranial magnetic stimulation in Alzheimer's disease: a network meta-analysis of randomized controlled trials. | Lasers in medical science |
| 2026-07-23 | PublicationImproved visual perception through visuomotor-coupled brain stimulation. | NeuroImage |
| 2026-07-23 | PublicationEnhanced home-based transcranial direct-current stimulation (tDCS) for depression comorbid with borderline personality disorder (BPD): study protocol for a pilot double-blinded randomised controlled trial (TENTADIS). | BMJ open |
| 2026-08-01 | Fin de l’étude prévue / enregistréeNCT06554067 | Registre d’essai clinique |
| 2026-08-01 | Début de l’étudeNCT07743814 | Registre d’essai clinique |
| 2026-08-05 | Création de l’enregistrementNCT03237754 | Registre d’essai clinique |
| 2026-08-08 | PublicationComparative Efficacy and Acceptability of Noninvasive Brain Stimulation for Migraine: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. | Brain and behavior |
| 2026-08-08 | PublicationHigh dosage accelerated intermittent theta burst stimulation without precision targeting and dosing in depression: an open-label pilot study. | European archives of psychiatry and clinical neuroscience |
| 2026-08-08 | PublicationCombined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop: A Case Series. | Journal of medical cases |
| 2026-08-08 | Publication"Additive Effects of Repetitive Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation on Robotic Therapy for Upper Extremity Recovery After Chronic Ischemic Stroke: A Randomized, Double-Blind, Sham-Controlled Trial". | Archives of physical medicine and rehabilitation |
| 2026-08-08 | PublicationThe effects of visuomotor training and tDCS stimulation on visuomotor integration and visual processing: an electrophysiological approach. | Neuroscience |
| 2026-08-08 | PublicationEffects of transcranial direct current stimulation and mindful walking on directional brain connectivity: An isolated effective coherence analysis. | Clinical neurophysiology practice |
| 2026-08-08 | PublicationThe Impact of Anodal tDCS on Verbal and Nonverbal Functional Communication in Subacute Aphasia-An Observational Study. | Brain sciences |
| 2026-08-08 | PublicationLong-Lasting Changes of Repeated Anodal Transcranial Direct Current Stimulation in Decreasing Chronic Pain in Patients with Multiple Sclerosis: A Case Series. | Brain sciences |
| 2026-08-13 | Création de l’enregistrementNCT06719947 | Registre d’essai clinique |
| 2026-08-13 | Création de l’enregistrementNCT04606095 | Registre d’essai clinique |
| 2026-08-13 | Création de l’enregistrementNCT07743814 | Registre d’essai clinique |
| 2026-08-13 | Création de l’enregistrementNCT06816004 | Registre d’essai clinique |
| 2026-08-13 | PublicationSwallowing therapy for dysphagia in acute and subacute stroke. | The Cochrane database of systematic reviews |
| 2026-08-13 | PublicationA Randomized Controlled Trial of Dual Upper-Extremity Training [DUET]: Combining Neurologic Music Therapy® with Noninvasive Brain Stimulation for Upper-Limb Performance in Corticobasal Syndrome. | Movement disorders clinical practice |
| 2026-08-13 | PublicationRemotely Supervised Home-Based tDCS in Treatment-Resistant Depression: Feasibility, Effectiveness and EEG Biomarkers of Response. | Psychiatry research |
| 2026-08-13 | PublicationDoes cathodal HD-tDCS-preconditioned iTBS over the contralesional dorsal premotor cortex improve upper limb motor function in patients with severe ischaemic stroke? A study protocol for a single-centre, participant-blinded and outcome assessor-blinded randomised controlled trial. | BMJ open |
| 2026-08-13 | PublicationCerebellar tDCS combined with augmented reality treadmill for freezing of gait in Parkinson's disease: a randomized controlled trial. | Journal of neuroengineering and rehabilitation |
| 2026-08-13 | PublicationCombined Transcranial Direct Current Stimulation With Sensory-Based Treatments in Autism: Preliminary Report. | American journal on intellectual and developmental disabilities |
| 2026-08-13 | PublicationDissociable neural mechanisms of cognitive enhancement through transcranial stimulation and behavioral training. | Brain research |
| 2026-08-13 | PublicationEfficacy and acceptability of noninvasive brain stimulation for treating posttraumatic stress disorder symptoms: A network meta-analysis of randomized controlled trials. | Acta psychiatrica Scandinavica |
| 2026-08-13 | PublicationLow intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017-2025: An update) - endorsed by the European Society for Brain Stimulation (ESBS) and by the International Federation for Clinical Neurophysiology (IFCN). | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology |
| 2026-08-13 | PublicationExploring the Effects of Remotely Supervised Transcranial Direct Current Stimulation on Motor Outcomes in Multiple Sclerosis: A Systematic Review. | NeuroRehabilitation |
| 2026-08-16 | Création de l’enregistrementNCT05958381 | Registre d’essai clinique |
| 2026-08-16 | Dernière mise à jour du registreNCT06719947 | Registre d’essai clinique |
| 2026-08-16 | PublicationCase Report: Anodal DLPFC-tDCS for refractory post-traumatic cognitive fatigue in the hypometabolic brain. | Frontiers in human neuroscience |
| 2026-08-16 | PublicationThe consequences of the new European reclassification of non-invasive brain stimulation devices and the medical device regulations pose an existential threat to research and treatment: An invited opinion paper. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology |
| 2026-08-16 | PublicationEffectiveness and safety of high-definition transcranial direct current stimulation in patients with mild cognitive impairment: A randomized, triple-blind, sham-controlled trial. | Journal of Alzheimer's disease : JAD |
| 2026-08-16 | PublicationAnodal HD-tDCS of vmPFC facilitates learning of monosemous and polysemous words: A computational modeling study. | Behavioural brain research |
| 2026-08-16 | Publication2 mA is NOT 2 mA: Electric field variability in high-definition tDCS and its implications for precision neuromodulation in aging. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology |
| 2026-08-16 | PublicationHigh-definition transcranial direct current stimulation enhances exercise-induced hypoalgesia in patients with chronic low back pain. | iScience |
| 2026-08-16 | PublicationTask-based fNIRS biomarkers of HD-tDCS treatment for negative symptoms in schizophrenia. | Schizophrenia research |
| 2026-08-16 | PublicationBaseline neurochemical excitability and individual differences in motor learning and non-invasive brain stimulation outcomes. | Cortex; a journal devoted to the study of the nervous system and behavior |
| 2026-08-16 | PublicationAcute stress alters prefrontal resting-state networks and tES restores functional connectivity. | Journal of affective disorders |
| 2026-08-16 | PublicationAssessing the effect of tDCS on inhibitory capacity: A pre-registered comparison of high definition and conventional montages on the stop signal task. | Cortex; a journal devoted to the study of the nervous system and behavior |
| 2026-08-16 | PublicationAge-related differences in how tDCS priming modulates cortical inhibition during fatigue recovery. | Neurobiology of aging |
| 2026-08-16 | PublicationDissociable roles of frontal electroencephalography markers in depression: Predictive value of frontal alpha asymmetry and responsive changes in beta power following home-based brain stimulation. | Journal of psychiatric research |
| 2026-08-16 | PublicationCognitive Strategy-based neuromodulation optimizes neural communication to improve working memory. | NeuroImage |
| 2026-08-16 | PublicationtDCS improves early Alzheimer's disease by synaptic vesicle fusion and release. | Military Medical Research |
| 2026-08-16 | PublicationTranscranial direct current stimulation enhances cognitive performance and modulates QEEG beta- and theta-band power in patients undergoing whole-brain radiotherapy. | IBRO neuroscience reports |
| 2026-08-16 | PublicationTelehealth tDCS to reduce cannabis use: A pilot RCT in multiple sclerosis as a framework for generalized use. | Drug and alcohol dependence |
| 2026-08-16 | PublicationThe Impact of Multiple Sessions of Anodal Transcranial Direct Current Stimulation on Implicit Motor Learning in High-Activity Older Adults: A Randomized Control Trial. | Journal of aging and physical activity |
| 2026-08-16 | PublicationThe oblique effect in visual working memory is enhanced by distraction, regardless of tDCS manipulations. | Cognitive, affective & behavioral neuroscience |
| 2026-08-26 | Création de l’enregistrementNCT06554067 | Registre d’essai clinique |
| 2026-09-14 | Création de l’enregistrementNCT06868160 | Registre d’essai clinique |
| 2026-09-14 | Création de l’enregistrementNCT07260253 | Registre d’essai clinique |
| 2026-09-14 | PublicationA randomized trial of a digitally delivered, home-based neuromodulation and mindfulness intervention for pain management in older adults with knee osteoarthritis. | NPJ digital medicine |
| 2026-09-14 | PublicationRemotely Supervised, Home-Based Transcranial Direct Current Stimulation for Major Depressive Disorder: Systematic Review and Meta-Analysis. | JMIR mental health |
| 2026-12-20 | Fin de l’étude prévue / enregistréeNCT04606095 | Registre d’essai clinique |
| 2027-01-31 | Fin de l’étude prévue / enregistréeNCT07743814 | Registre d’essai clinique |
| 2027-05-05 | Fin de l’étude prévue / enregistréeNCT06816004 | Registre d’essai clinique |
| 2027-06-29 | Fin de l’étude prévue / enregistréeNCT05958381 | Registre d’essai clinique |
| 2028-09-01 | Fin de l’étude prévue / enregistréeNCT06719947 | Registre d’essai clinique |
| 2029-01-01 | Fin de l’étude prévue / enregistréeNCT06868160 | Registre d’essai clinique |
| 2030-04-30 | Fin de l’étude prévue / enregistréeNCT07260253 | Registre d’essai clinique |
Début phase actuelle
Non disponible dans les sources synchronisées
Essais cliniques liés
13 essai(s)
Début phase actuelle
Non disponible dans les sources synchronisées
| NCT | Titre | Phase | Statut administratif | Pays | Sponsor |
|---|---|---|---|---|---|
| NCT06868160 | Comparison of Different Non-invasive Electrical Stimulation Protocols to Facilitate Rehabilitation in Parkinson's Disease Subjects With Postural Instability and Gait Disorders | Non applicable | RECRUITING | Italy | IRCCS San Raffaele |
| NCT07260253 | Remotely-supervised Neuromodulation in PPA | Non applicable | RECRUITING | United States | Maya Henry |
| NCT06554067 | Effects of tDCS and VNS on Postoperative Analgesia | Non applicable | NOT_YET_RECRUITING | Non communiqué | Columbia University |
| NCT05958381 | MS-HDtDCS — Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation | Non applicable | RECRUITING | United States | The University of Texas at Dallas |
| NCT06719947 | tDCS-ALS — HD-tDCS in Amyotrophic Lateral Sclerosis: A Multicenter Randomized Controlled Trial | Phase 2/3 | RECRUITING | Brazil, Chile | Universidade Federal do Rio Grande do Norte |
| NCT04606095 | Explosive Synchronization of Brain Network Activity in Chronic Pain | Non applicable | ACTIVE_NOT_RECRUITING | United States | University of Michigan |
| NCT07743814 | EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) OF PRIMARY MOTOR CORTEX ON HEADACHE FREQUENCY IN PATIENTS WITH CHRONIC MIGRAINE | Phase 3 | NOT_YET_RECRUITING | India | Dr. Ram Manohar Lohia Hospital |
| NCT06816004 | VANISH-MS — Noninvasive Vagal Nerve Stimulation | Non applicable | ACTIVE_NOT_RECRUITING | United States | NYU Langone Health |
| NCT03237754 | Neurostimulation in Chronic and Episodic Migraine | NA | TERMINATED | Switzerland | University of Zurich |
| NCT00521196 | Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine) | NA | COMPLETED | United States | Beth Israel Deaconess Medical Center |
| NCT02263274 | Direct Cortical Measurement of the Intensity and Pattern of Current Flow Produced by TDCS | NA | COMPLETED | United States | NYU Langone Health |
| NCT02315781 | tDCS in Parkinson's Disease With Depression | NA | TERMINATED | Canada | Pacific Parkinson's Research Centre |
| NCT02538094 | tDCS and Cognition in Adults With Multiple Sclerosis or Encephalitis | NA | COMPLETED | United States | Johns Hopkins University |
Publications liées
59 publication(s)Publications liées
59 publication(s)| Titre | PMID | DOI | Journal | Date |
|---|---|---|---|---|
| A randomized trial of a digitally delivered, home-based neuromodulation and mindfulness intervention for pain management in older adults with knee osteoarthritis. Voir source | 41917434 | 10.1038/s41746-026-02577-7 | NPJ digital medicine | |
| Remotely Supervised, Home-Based Transcranial Direct Current Stimulation for Major Depressive Disorder: Systematic Review and Meta-Analysis. Voir source | 42696738 | 10.2196/92522 | JMIR mental health | |
| Case Report: Anodal DLPFC-tDCS for refractory post-traumatic cognitive fatigue in the hypometabolic brain. Voir source | 42602261 | 10.3389/fnhum.2026.1919849 | Frontiers in human neuroscience | |
| The consequences of the new European reclassification of non-invasive brain stimulation devices and the medical device regulations pose an existential threat to research and treatment: An invited opinion paper. Voir source | 38679530 | 10.1016/j.clinph.2024.03.039 | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | |
| Effectiveness and safety of high-definition transcranial direct current stimulation in patients with mild cognitive impairment: A randomized, triple-blind, sham-controlled trial. Voir source | 40984052 | 10.1177/13872877251376547 | Journal of Alzheimer's disease : JAD | |
| Anodal HD-tDCS of vmPFC facilitates learning of monosemous and polysemous words: A computational modeling study. Voir source | 41547404 | 10.1016/j.bbr.2026.116042 | Behavioural brain research | |
| 2 mA is NOT 2 mA: Electric field variability in high-definition tDCS and its implications for precision neuromodulation in aging. Voir source | 41966869 | 10.1016/j.clinph.2026.2111877 | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | |
| High-definition transcranial direct current stimulation enhances exercise-induced hypoalgesia in patients with chronic low back pain. Voir source | 42403639 | 10.1016/j.isci.2026.116443 | iScience | |
| Task-based fNIRS biomarkers of HD-tDCS treatment for negative symptoms in schizophrenia. Voir source | 42000633 | 10.1016/j.schres.2026.04.010 | Schizophrenia research | |
| Baseline neurochemical excitability and individual differences in motor learning and non-invasive brain stimulation outcomes. Voir source | 42263535 | 10.1016/j.cortex.2026.05.009 | Cortex; a journal devoted to the study of the nervous system and behavior | |
| Acute stress alters prefrontal resting-state networks and tES restores functional connectivity. Voir source | 42142754 | 10.1016/j.jad.2026.121976 | Journal of affective disorders | |
| Assessing the effect of tDCS on inhibitory capacity: A pre-registered comparison of high definition and conventional montages on the stop signal task. Voir source | 42275807 | 10.1016/j.cortex.2026.05.011 | Cortex; a journal devoted to the study of the nervous system and behavior | |
| Age-related differences in how tDCS priming modulates cortical inhibition during fatigue recovery. Voir source | 42284970 | 10.1016/j.neurobiolaging.2026.06.001 | Neurobiology of aging | |
| Dissociable roles of frontal electroencephalography markers in depression: Predictive value of frontal alpha asymmetry and responsive changes in beta power following home-based brain stimulation. Voir source | 42341411 | 10.1016/j.jpsychires.2026.06.030 | Journal of psychiatric research | |
| Cognitive Strategy-based neuromodulation optimizes neural communication to improve working memory. Voir source | 42392337 | 10.1016/j.neuroimage.2026.122104 | NeuroImage | |
| tDCS improves early Alzheimer's disease by synaptic vesicle fusion and release. Voir source | 41953054 | 10.1016/j.mmr.2026.100003 | Military Medical Research | |
| Transcranial direct current stimulation enhances cognitive performance and modulates QEEG beta- and theta-band power in patients undergoing whole-brain radiotherapy. Voir source | 42598132 | 10.1016/j.ibneur.2026.07.021 | IBRO neuroscience reports | |
| Telehealth tDCS to reduce cannabis use: A pilot RCT in multiple sclerosis as a framework for generalized use. Voir source | 40378662 | 10.1016/j.drugalcdep.2025.112706 | Drug and alcohol dependence | |
| The Impact of Multiple Sessions of Anodal Transcranial Direct Current Stimulation on Implicit Motor Learning in High-Activity Older Adults: A Randomized Control Trial. Voir source | 41130445 | 10.1123/japa.2024-0281 | Journal of aging and physical activity | |
| The oblique effect in visual working memory is enhanced by distraction, regardless of tDCS manipulations. Voir source | 42014668 | 10.3758/s13415-026-01443-z | Cognitive, affective & behavioral neuroscience | |
| Swallowing therapy for dysphagia in acute and subacute stroke. Voir source | 42573047 | 10.1002/14651858.CD000323.pub4 | The Cochrane database of systematic reviews | |
| A Randomized Controlled Trial of Dual Upper-Extremity Training [DUET]: Combining Neurologic Music Therapy® with Noninvasive Brain Stimulation for Upper-Limb Performance in Corticobasal Syndrome. Voir source | 42438177 | 10.1002/mdc3.70734 | Movement disorders clinical practice | |
| Remotely Supervised Home-Based tDCS in Treatment-Resistant Depression: Feasibility, Effectiveness and EEG Biomarkers of Response. Voir source | 42580014 | 10.1016/j.psychres.2026.117360 | Psychiatry research | |
| Does cathodal HD-tDCS-preconditioned iTBS over the contralesional dorsal premotor cortex improve upper limb motor function in patients with severe ischaemic stroke? A study protocol for a single-centre, participant-blinded and outcome assessor-blinded randomised controlled trial. Voir source | 42586729 | 10.1136/bmjopen-2026-120996 | BMJ open | |
| Cerebellar tDCS combined with augmented reality treadmill for freezing of gait in Parkinson's disease: a randomized controlled trial. Voir source | 39342307 | 10.1186/s12984-024-01457-z | Journal of neuroengineering and rehabilitation | |
| Combined Transcranial Direct Current Stimulation With Sensory-Based Treatments in Autism: Preliminary Report. Voir source | 42580310 | 10.1080/19447515.2025.2576435 | American journal on intellectual and developmental disabilities | |
| Dissociable neural mechanisms of cognitive enhancement through transcranial stimulation and behavioral training. Voir source | 42586193 | 10.1016/j.brainres.2026.150505 | Brain research | |
| Efficacy and acceptability of noninvasive brain stimulation for treating posttraumatic stress disorder symptoms: A network meta-analysis of randomized controlled trials. Voir source | 38616056 | 10.1111/acps.13688 | Acta psychiatrica Scandinavica | |
| Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017-2025: An update) - endorsed by the European Society for Brain Stimulation (ESBS) and by the International Federation for Clinical Neurophysiology (IFCN). Voir source | 41622107 | 10.1016/j.clinph.2025.2111436 | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | |
| Exploring the Effects of Remotely Supervised Transcranial Direct Current Stimulation on Motor Outcomes in Multiple Sclerosis: A Systematic Review. Voir source | 41960941 | 10.1177/10538135261436051 | NeuroRehabilitation | |
| Comparative Efficacy and Acceptability of Noninvasive Brain Stimulation for Migraine: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Voir source | 42473074 | 10.1002/brb3.71566 | Brain and behavior | |
| High dosage accelerated intermittent theta burst stimulation without precision targeting and dosing in depression: an open-label pilot study. Voir source | 40705070 | 10.1007/s00406-025-02067-z | European archives of psychiatry and clinical neuroscience | |
| Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop: A Case Series. Voir source | 42564268 | 10.14740/jmc5333 | Journal of medical cases | |
| "Additive Effects of Repetitive Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation on Robotic Therapy for Upper Extremity Recovery After Chronic Ischemic Stroke: A Randomized, Double-Blind, Sham-Controlled Trial". Voir source | 42562200 | 10.1016/j.apmr.2026.07.026 | Archives of physical medicine and rehabilitation | |
| The effects of visuomotor training and tDCS stimulation on visuomotor integration and visual processing: an electrophysiological approach. Voir source | 42501781 | 10.1016/j.neuroscience.2026.07.048 | Neuroscience | |
| Effects of transcranial direct current stimulation and mindful walking on directional brain connectivity: An isolated effective coherence analysis. Voir source | 42502737 | 10.1016/j.cnp.2026.07.006 | Clinical neurophysiology practice | |
| The Impact of Anodal tDCS on Verbal and Nonverbal Functional Communication in Subacute Aphasia-An Observational Study. Voir source | 42512501 | 10.3390/brainsci16070727 | Brain sciences | |
| Long-Lasting Changes of Repeated Anodal Transcranial Direct Current Stimulation in Decreasing Chronic Pain in Patients with Multiple Sclerosis: A Case Series. Voir source | 42512541 | 10.3390/brainsci16070767 | Brain sciences | |
| Comparative efficacy and safety of photobiomodulation, transcranial direct current stimulation, and repetitive transcranial magnetic stimulation in Alzheimer's disease: a network meta-analysis of randomized controlled trials. Voir source | 42487022 | 10.1007/s10103-026-04962-w | Lasers in medical science | |
| Improved visual perception through visuomotor-coupled brain stimulation. Voir source | 42456796 | 10.1016/j.neuroimage.2026.122134 | NeuroImage | |
| Enhanced home-based transcranial direct-current stimulation (tDCS) for depression comorbid with borderline personality disorder (BPD): study protocol for a pilot double-blinded randomised controlled trial (TENTADIS). Voir source | 42476741 | 10.1136/bmjopen-2026-117392 | BMJ open | |
| Adjunctive transcranial DC stimulation in the management of refractory drug-resistant focal epilepsy in POLG mitochondrial disease: A case series. Voir source | 42248710 | 10.1016/j.seizure.2026.05.009 | Seizure | |
| The Additive Effects of Transcranial Direct Current Stimulation Combined With Exercise-Based Rehabilitation Interventions on Balance, Ankle Kinematics, and Muscle Activity in Individuals With Ankle Instability: A Systematic Review. Voir source | 42482792 | 10.1002/hsr2.72833 | Health science reports | |
| Prefrontal transcranial direct current stimulation in alcohol use disorder: a pilot randomized sham-controlled trial with exploratory effects on reward craving and depressive symptoms. Voir source | 42475940 | 10.1016/j.addbeh.2026.108798 | Addictive behaviors | |
| Increased brain glucose metabolism after anodal left DLPFC-right shoulder tDCS in ASD: an open-label pilot F-18 FDG PET/CT study. Voir source | 42477631 | 10.1186/s12888-026-08418-x | BMC psychiatry | |
| Effects of concurrent transcranial direct current stimulation on human motor skill learning: A systematic review and Bayesian meta-analysis. Voir source | 42463027 | 10.1016/j.bbr.2026.116378 | Behavioural brain research | |
| Training-induced cognitive coupling emerges under sham but not active transcranial electrical stimulation in older adults: a triple-blind, randomized, sham-controlled study. Voir source | 42449402 | 10.1186/s12984-026-02077-5 | Journal of neuroengineering and rehabilitation | |
| Heterogeneous Recruitment Curve Responses to Anodal Transcranial Direct Current Stimulation in Children With Unilateral Spastic Cerebral Palsy. Voir source | 42464518 | 10.1177/15459683261464051 | Neurorehabilitation and neural repair | |
| Comparative Efficacy of Non-invasive Brain Stimulation for Pain, Anxiety, and Depression: A Systematic Review and Network Meta-analysis. Voir source | 42435147 | 10.1007/s40122-026-00860-9 | Pain and therapy | |
| Effect of transcranial direct current stimulation on psychomotor skill acquisition during laparoscopic training: a randomized controlled trial. Voir source | 42443692 | 10.1007/s00464-026-12992-2 | Surgical endoscopy | |
| Does Anodal Transcranial Direct Current Stimulation Over the Primary Motor Cortex Really Enhance Motor Sequence Learning? Voir source | 42438490 | 10.1016/j.bpsgos.2026.100766 | Biological psychiatry global open science | |
| Sham tDCS controls: blinding, reliability, and a specification-grade checklist. Voir source | 42164710 | 10.3389/fnhum.2026.1742370 | Frontiers in human neuroscience | |
| Effects of transcranial direct current stimulation on Nicotine Use Disorder: A systematic review and meta-analysis. Voir source | 42384937 | 10.1093/ntr/ntag152 | Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco | |
| Efficacy of transcranial direct current stimulation for post-stroke urinary incontinence: study protocol for a randomized controlled trial. Voir source | 42393784 | 10.1186/s13063-026-09866-2 | Trials | |
| Intensive Rehabilitation With Adjunctive Bilateral Anodal tDCS in Post-Stroke Dysphagia: A Multicenter Randomized Controlled Trial. Voir source | 42383625 | 10.1111/ene.70686 | European journal of neurology | |
| The role of inferior frontal gyrus in emotion regulation: Evidence from fMRI and tDCS investigation. Voir source | 42385998 | 10.1016/j.ijpsycho.2026.113438 | International journal of psychophysiology : official journal of the International Organization of Psychophysiology | |
| Effects of transcranial electric stimulation on attentional functions in healthy adults: A meta-analysis. Voir source | 42402271 | 10.1016/j.biopsycho.2026.109342 | Biological psychology | |
| Concurrent effects of EMG-triggered NMES and anodal tDCS on cortical and behavioural outcome measures: The role of ipsilateral versus contralateral anodal stimulation. Voir source | 42431572 | 10.1016/j.brainres.2026.150464 | Brain research | |
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Sources officielles
liens de rechercheDernière mise à jour des données : 2025-11-25
Ces sources sont proposées pour vérification. Les informations de la fiche doivent être confirmées dans les registres officiels ou les publications originales.