Fiche traitement
Immunoglobulin
National Eye Institute (NEI) • SEP
Suivi actif
Phase 3
Résumé
Immunoglobulin est développé par National Eye Institute (NEI). Le traitement est actuellement en Phase 3. Il est associé à SEP. Son objectif thérapeutique principal est Remyélinisation. Le statut actuel est : suivi actif.
À vérifier
Remyélinisation
Phase 3
National Eye Institute (NEI)
United States
To determine whether high-dose intravenous immunoglobulin (IVIg) is more effective than placebo in restoring lost visual function (visual acuity) in optic neuritis (ON).
To determine the time course of recovery following IVIg administration. If the reports of IVIg-associated clinical improvement occurring within 3 to 6 months following treatment can be confirmed, this would provide indirect evidence that IVIg may promote central nervous system (CNS) remyelination in optic neuritis and multiple sclerosis (MS).
2009-09-16
Début phase actuelle
Non disponible dans les sources synchronisées
Timeline clinique
Phase 3
Début phase actuelle
Non disponible dans les sources synchronisées
Préclinique
Phase 1
Phase 2
Phase 3
Approuvé
Objectif scientifique de l’étude
classification automatique vérifiable
Remyélinisation
Confiance automatique : 80%
Ce pourcentage n’est pas une probabilité de succès clinique.
Il mesure uniquement la force de la classification automatique de l’objectif scientifique. Le calcul part de 45 points, ajoute 7 points par unité de poids du mot-clé le plus fortement détecté, puis est plafonné à 95 %. Exemple : un score maximal de 2 donne 45 + (2 × 7) = 59 %.
Indices détectés : remyelin → Remyélinisation
Ce score est heuristique et doit être vérifié dans le protocole ou une publication.
Description affichée depuis l’essai compatible NCT00000117, afin d’éviter le mélange entre plusieurs indications d’une même molécule.
Aucune incohérence majeure détectée entre la maladie, l’objectif et la description.
Transparence et qualité de la fiche
données vérifiablesClassificationCohérente automatiquement
Confiance de la fiche100 %
Source principaleSource officielle ou publication indexée
Dernière vérification2009-09-16
Anomalies détectées0
Validation humaineValidation humaine non effectuée
Donnée issue d’une source
Donnée normalisée automatiquement
Interprétation algorithmique
Classification scientifique multi-axes
ne pas confondre statut et résultatÉtat de l’étudeTerminée
Disponibilité des résultatsRésultats à vérifier
InterprétationImpossible à déterminer
Niveau de preuveNon évaluable
Un essai terminé n’est pas nécessairement positif. Un essai arrêté n’est classé comme échec scientifique que lorsqu’un résultat ou une raison explicite le confirme.
Indicateurs factuels
sans score subjectifPhase enregistréePhase 3
Études associées1
Publications associées97
Statut consolidéSuivi actif
Aucune chance de succès, note d’innovation, potentiel thérapeutique ou probabilité de commercialisation n’est calculé tant qu’un modèle validé et des données suffisantes ne sont pas disponibles.
Historique factuel de la molécule
101 événement(s) daté(s)Cette liste reprend uniquement les dates trouvées dans les registres et publications liés. Elle ne constitue pas une prévision.
| Date | Événement | Source |
|---|---|---|
| 1995-08-01 | Début de l’étudeNCT00000117 | Registre d’essai clinique |
| 1997-12-01 | Fin de l’étude prévue / enregistréeNCT00000117 | Registre d’essai clinique |
| 2009-09-16 | Dernière mise à jour des donnéesImmunoglobulin | Biomedical Watch |
| 2026-07-08 | PublicationSteroid-Sparing Effect of Efgartigimod in Generalized Myasthenia Gravis: Study Protocol for a Single-Arm, Open-Label Clinical Trial. | Neurology and therapy |
| 2026-07-10 | PublicationPridopidine Protects ALS Patient-Derived Neural Progenitor Cells via Sigma-1 Receptor Activation. | International journal of molecular sciences |
| 2026-07-10 | Publication[Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits (PGNMID) Associated with Marginal Zone B-cell Lymphoma: A Case of MGRS in a Patient with Nephrotic Syndrome and Rapidly Progressive Renal Failure]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia |
| 2026-07-10 | PublicationEarly postoperative onset of immune thrombocytopenia in rheumatoid arthritis with concomitant systemic lupus erythematosus: a case report. | Modern rheumatology case reports |
| 2026-07-10 | PublicationAdjuvant intravenous immunoglobulin in elderly sepsis: a randomized controlled study of mortality, organ function, and inflammation. | Frontiers in medicine |
| 2026-07-12 | PublicationFulminant toxic epidermal necrolysis induced by pucotenlimab in a patient with lung adenocarcinoma: a case report. | Frontiers in oncology |
| 2026-07-12 | PublicationGuillain-Barré Syndrome Following Dengue Infection: A Case Series with Review of Literature. | Annals of neurosciences |
| 2026-07-12 | PublicationChorea as a Non-Thrombotic Manifestation in an Adolescent with Systemic Lupus Erythematosus, Antiphospholipid Syndrome and Heterozygous Prothrombin G20210A Gene Mutation: A Case Report. | Case reports in neurology |
| 2026-07-12 | PublicationNovel pathological genetic variant associated with DOCK8 deficiency: case report with successful hematopoietic stem cell transplantation. | Allergologia et immunopathologia |
| 2026-07-12 | PublicationPrecision myeloablation with TDM-guided busulfan in pediatric primary immunodeficiencies: a real-world study of 28 patients. | Translational pediatrics |
| 2026-07-12 | PublicationNasal Manifestations of Immunoglobulin A (IgA) Vasculitis in an Adolescent Patient: A Case Report. | Cureus |
| 2026-07-12 | PublicationAntimetabolites synergize with non-genotoxic antibody drug conjugate conditioning in hematopoietic stem cell lentiviral gene therapy. | Molecular therapy. Advances |
| 2026-07-12 | PublicationWest Nile Neuroinvasive Disease: Current Management, Emerging Therapies and Future Clinical Trial Priorities. | Reviews in medical virology |
| 2026-07-14 | PublicationCase of concurrent ALS and human T-cell leukaemia virus type 1-associated myositis. | BMJ case reports |
| 2026-07-14 | PublicationCase Report: Stevens-Johnson syndrome/toxic epidermal necrolysis overlap with ocular and urogenital involvement in an extremely preterm infant following broad-spectrum antibiotic exposure. | Frontiers in medicine |
| 2026-07-14 | PublicationReal-world experience with switching from intravenous immunoglobulin to subcutaneous efgartigimod PH20 in patients with chronic inflammatory demyelinating polyradiculoneuropathy: A case series. | Journal of neuroimmunology |
| 2026-07-14 | PublicationFulminant paraneoplastic Ma2 (PNMA2) and zinc finger protein of the cerebellum 4 (ZIC4) antibody-positive encephalitis in triple-negative breast cancer treated with pembrolizumab. | BMJ case reports |
| 2026-07-14 | PublicationRandomized Double-Blind Placebo-Controlled Trial of the Corticosteroid-Sparing Effects of Immunoglobulin in Myasthenia Gravis. | Neurology |
| 2026-07-14 | PublicationEfficacy and safety of maintenance intravenous immunoglobulin in generalized myasthenia gravis patients with acetylcholine receptor antibodies: A multicenter, double-blind, placebo-controlled trial. | Muscle & nerve |
| 2026-07-14 | PublicationIntravenous Immunoglobulin-Resistant Kawasaki Disease: Diagnosis, Mechanisms, and Clinical Management. | European journal of pharmacology |
| 2026-07-14 | PublicationPeripheral blood immunoglobulin A level is independently negatively correlated with renal involvement in newly diagnosed childhood systemic lupus erythematosus: a single-center cross-sectional study based on 380 pediatric lupus nephritis patients in southwest China. | Clinical rheumatology |
| 2026-07-14 | PublicationPurpura as the initial manifestation of IgG4-related disease with concomitant systemic lupus erythematosus: a case report. | Frontiers in medicine |
| 2026-07-15 | PublicationAlleviation effect of Potentilla anserina polysaccharides on intestinal barrier dysfunction and its underlying mechanism. | International journal of biological macromolecules |
| 2026-07-18 | PublicationPovetacicept (ALPN-303; TACI vTD-Fc), an enhanced, potent dual inhibitor of BAFF and APRIL, ameliorates experimental autoimmune myasthenia gravis in C57BL/6N mice. | Frontiers in immunology |
| 2026-07-18 | PublicationA case report of Good syndrome: Diarrhea and dyspnea. | Medicine |
| 2026-07-18 | PublicationKnowledge graph visualization and bibliometric analysis of research on coronary artery lesions in Kawasaki disease. | Medicine |
| 2026-07-18 | PublicationImmunological Dynamics and Outcomes of ABO-Incompatible Kidney Transplants: Insights From a 5+-Year Follow-Up at a Transplant-Heavy Tertiary Center in Saudi Arabia. | Journal of transplantation |
| 2026-07-18 | Publication36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016. | Critical care (London, England) |
| 2026-07-22 | PublicationTelitacicept, a novel humanized, recombinant TACI-Fc fusion protein, for the treatment of systemic lupus erythematosus. | Drugs of today (Barcelona, Spain : 1998) |
| 2026-07-22 | PublicationGuillain-Barré syndrome with bilateral extensor plantar responses: A rare case report. | Journal of family medicine and primary care |
| 2026-07-22 | PublicationCase Report: Hereditary thrombotic thrombocytopenic purpura mimicking immune thrombocytopenia: diagnostic pitfalls of whole-exome sequencing. | Frontiers in pediatrics |
| 2026-07-22 | PublicationIntegrating Cerebrospinal Fluid Metagenomic Next-Generation Sequencing and Immune Profiling in Recurrent HSV-1 Encephalitis: A Case Report and Narrative Review. | Journal of child neurology |
| 2026-07-23 | PublicationImmunoglobulin G4-Related Sclerosing Cholangitis: A Review. | Clinics in liver disease |
| 2026-07-23 | PublicationEvaluation of the humoral response during ocrelizumab therapy in multiple sclerosis - an observational study. | Neurologia i neurochirurgia polska |
| 2026-08-08 | PublicationConcurrent herpetic hypertensive anterior uveitis and cytomegalovirus retinitis in a non-HIV patient with melanoma differentiation-associated gene-5 dermatomyositis: intravenous immunoglobulin comes to the rescue. | Reumatismo |
| 2026-08-08 | PublicationAbdominal Wall Erythema as a Suspected Extracardiac Manifestation of Cardiac Allograft Rejection. | Cureus |
| 2026-08-08 | PublicationSafety and tolerability of a new intravenous immunoglobulin 10% in patients with primary immunodeficiency. | Immunotherapy |
| 2026-08-08 | PublicationEffects of the active amyloid beta immunotherapy CAD106 on PET measurements of amyloid plaque deposition in cognitively unimpaired APOE ε4 homozygotes. | Alzheimer's & dementia : the journal of the Alzheimer's Association |
| 2026-08-08 | PublicationUltrasound-Guided Stellate Ganglion and Interscalene Blocks for Refractory Pediatric Parsonage-Turner Syndrome: A Case Report and Clinical Implications. | Pain medicine case reports |
| 2026-08-08 | PublicationParoxysmal Speech Arrest With Resolving Splenial and Symmetric White Matter Lesions in a Child: A Case Report. | Cureus |
| 2026-08-08 | PublicationAcute Attack Treatment Escalation and Subsequent Relapse Risk in Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. | Neurology |
| 2026-08-08 | PublicationDifferential safety profiles of disease-modifying therapies in MS: Age- and sex-based analysis from a real-world cohort. | Multiple sclerosis and related disorders |
| 2026-08-08 | PublicationLymphoplasmapheresis for Refractory Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report. | Journal of clinical apheresis |
| 2026-08-08 | PublicationA High-dose Pharmacokinetic Study of a New IgG4 Monoclonal Antibody Temelimab/GNbAC1 Antagonist of an Endogenous Retroviral Protein pHERV-W Env. | Clinical therapeutics |
| 2026-08-13 | PublicationTransient Neonatal Myasthenia Gravis in a Newborn Infant Presenting to an Emergency Department. | Cureus |
| 2026-08-13 | PublicationWhen Neurodevelopment Meets Autoimmunity: Pemphigus Foliaceus in Rett Syndrome Expands the Clinical Spectrum-A Case Report. | International journal of molecular sciences |
| 2026-08-13 | PublicationNew and Emerging Nonimmunosuppressive Drug Therapies for Primary Adult Glomerular Diseases. | Kidney medicine |
| 2026-08-13 | PublicationObinutuzumab β for aquaporin-4-positive neuromyelitis optica spectrum disorder: a phase 3 randomized controlled trial. | Nature medicine |
| 2026-08-13 | PublicationManagement of Exacerbations and Rescue Therapy: A Prespecified Analysis of the Phase 3 Myasthenia Gravis Inebilizumab Randomized Clinical Trial. | JAMA neurology |
| 2026-08-13 | PublicationUrticaria as a dermatologic manifestation of Giardia infection: a systematic review of clinical, diagnostic, and therapeutic features. | BMC infectious diseases |
| 2026-08-13 | PublicationEfficacy and safety of emerging immunomodulatory agents versus standard therapies in refractory cutaneous lupus: A systematic review. | Dermatology online journal |
| 2026-08-13 | PublicationBK Polyomavirus-Associated Nephropathy Complicated by Life-Threatening Hemorrhagic Pericardial Effusion Following Immunosuppression Reduction in a Kidney Transplant Recipient: A Case Report. | Case reports in transplantation |
| 2026-08-13 | PublicationFormation and preliminary characterization of mercury-reactive immunoglobulin Y antibodies in laying hens using HgCl-protein hapten conjugates. | Veterinary world |
| 2026-08-13 | PublicationImmunotherapy Resistance in dMMR/MSI-H Colorectal Cancer: Unraveling Mechanisms and Exploring Overcoming Strategies. | Journal of immunology research |
| 2026-08-13 | PublicationImmunoglobulin Superfamily Protein BTNL9 Functions as a Non-Canonical Transcriptional Regulator to Suppress NSCLC Through Cell Cycle and p53 Pathways. | International journal of molecular sciences |
| 2026-08-13 | PublicationCase Report of Combined Central and Peripheral Demyelination: Treated With Ofatumumab. | Immunity, inflammation and disease |
| 2026-08-13 | PublicationProbable Autoimmune Encephalitis Presenting With Catatonia in a Young Woman: A Case Report and Review of the Literature. | International journal of psychiatry in medicine |
| 2026-08-13 | PublicationAQP4-IgG-positive myelitis occurring in a patient with small cell lung cancer: a case report. | Frontiers in oncology |
| 2026-08-13 | PublicationImmune thrombocytopenia: Evolving mechanistic understanding and clinical development of new therapies. | Tzu chi medical journal |
| 2026-08-13 | PublicationEculizumab treatment in the salvage therapy of MOGAD: a case report. | Frontiers in immunology |
| 2026-08-16 | PublicationEffects of wildfire smoke exposure on health parameters and inflammatory responses of beef-on-dairy calves. | Journal of animal science |
| 2026-08-16 | PublicationPreclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseases. | Frontiers in immunology |
| 2026-08-16 | PublicationImpact of antiviral treatment and initiation time on mother-to-child transmission in pregnant women with extremely high HBV DNA loads. | Virulence |
| 2026-08-16 | PublicationClinical characteristics and diagnostic indicators of childhood-onset systemic lupus erythematosus complicated with macrophage activation syndrome. | Clinical rheumatology |
| 2026-08-16 | PublicationPatient perspectives on hemolytic disease of the fetus and newborn and fetal and neonatal alloimmune thrombocytopenia: common experiences and insights. | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians |
| 2026-08-16 | PublicationAnalysis of the expression changes of IL-17+ γδ T cells and Treg cells in bone marrow mesenchymal stem cells targeted therapy for allergic rhinitis. | European review for medical and pharmacological sciences |
| 2026-08-16 | PublicationAnti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial. | The Lancet. Respiratory medicine |
| 2026-08-16 | PublicationA Comparative Real-World Study Evaluating the Safety of Immune Globulin Infusion (Human) 10% Solution and Other Intravenous Immunoglobulin Therapies for the Treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy. | Pharmacoepidemiology and drug safety |
| 2026-08-16 | PublicationThe Results of ADVANCE-CIDP IVIG Trial: Intravenous Immunoglobulin 10% Therapy With GAMMAGARD LIQUID/Kiovig for Treatment of Relapse in Chronic Inflammatory Demyelinating Polyradiculoneuropathy. | European journal of neurology |
| 2026-08-16 | PublicationClinical features, imaging findings, and treatment outcomes of optic neuritis associated with anti-CRMP5 antibodies: a systematic review. | Journal of neuroimmunology |
| 2026-08-16 | PublicationNeuro-renal syndrome (NRS) in autoimmune nodopathies and paranodopathies: A warning to consider the diagnosis when anti-node and paranode antibody tests are difficult to perform. | Journal of the neurological sciences |
| 2026-08-16 | PublicationRisk factors for hypotension and technical complications during single-session double-filtration plasmapheresis: a 15-year retrospective study of 1,022 procedures. | Renal failure |
| 2026-08-16 | PublicationThe role of cardiac PET imaging in cardiac amyloidosis. | Seminars in nuclear medicine |
| 2026-08-16 | PublicationAssociation of anti-glycolipid IgG with respiratory function decline in amyotrophic lateral sclerosis. | Journal of the neurological sciences |
| 2026-08-16 | PublicationAnti-GAD65 antibody-associated cerebellar ataxia in a young adult with type 1 diabetes: a case report and literature review. | Diabetology international |
| 2026-08-16 | PublicationThe economic value of self-administered subcutaneous immunoglobulin G (SCIg) in Canada: a scoping review. | Journal of medical economics |
| 2026-08-16 | PublicationResults of a randomized double-blind placebo-controlled Phase 2 study propose iptacopan as an alternative complement pathway inhibitor for IgA nephropathy. | Kidney international |
| 2026-08-16 | PublicationNipocalimab and other FcRn blockers in neuromuscular disorders. | Pharmacology & therapeutics |
| 2026-08-16 | PublicationEffect of nipocalimab on IgG responses to vaccinations and viral infections in patients with IgG autoantibody-mediated diseases: Post hoc analyses of three randomized, placebo-controlled trials. | Human vaccines & immunotherapeutics |
| 2026-08-16 | PublicationCorticosteroids and mycophenolic acid analogues in immunoglobulin A nephropathy with progressive decline in kidney function. | Clinical kidney journal |
| 2026-08-16 | PublicationShared genetics of IgA nephropathy and cardiometabolic diseases revealed by integrative genomic analysis. | Renal failure |
| 2026-08-16 | PublicationEfficacy and Safety of Subcutaneous Belimumab in Anti-Double-Stranded DNA-Positive, Hypocomplementemic Patients With Systemic Lupus Erythematosus. | Arthritis & rheumatology (Hoboken, N.J.) |
| 2026-08-16 | PublicationProtein L: a novel reagent for the detection of chimeric antigen receptor (CAR) expression by flow cytometry. | Journal of translational medicine |
| 2026-08-16 | PublicationResolution of Neuroblastoma-Related Opsoclonus-Myoclonus Ataxia Syndrome Following Tandem High-Dose Chemotherapy With Autologous Hematopoietic Stem Cell Transplantation and Extensive Intravenous Immunoglobulin. | Pediatric blood & cancer |
| 2026-08-16 | PublicationVitreoretinal Lymphoma: A Comprehensive Clinical Review and Current Standards in Management. | Journal of vitreoretinal diseases |
| 2026-08-16 | PublicationProliferative glomerulonephritis with monoclonal IgG3 deposits: A case series. | Journal of translational autoimmunity |
| 2026-08-16 | PublicationA case of drug-induced bullous pemphigoid secondary to immunotherapy treated with upadacitinib: A case report. | SAGE open medical case reports |
| 2026-08-16 | PublicationOfatumumab Treatment Used in Pediatric MOGAD: A Retrospective Case Series. | Journal of central nervous system disease |
| 2026-08-16 | PublicationIntravenous immunotherapy with Der p 1-containing nanoparticles alleviates the allergic responses in a murine allergic rhinitis model. | Human vaccines & immunotherapeutics |
| 2026-08-16 | Publicationtype B (Hib) necrotizing soft tissue infection (NSTI) in a vaccinated 16-month-old Inuit boy: a case report. | International journal of circumpolar health |
| 2026-08-16 | PublicationA multiple ascending dose, phase1b study to evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of lesigercept, a long-acting IgE-Fc fusion protein, in participants with atopy or allergic diseases. | International immunopharmacology |
| 2026-08-16 | PublicationSuccessful treatment of pure red cell aplasia with Orelabrutinib following major ABO-incompatible hematopoietic stem cell transplantation for acute myeloid leukemia: A case report. | Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis |
| 2026-08-16 | PublicationImmunoglobulin dynamics and infection risk with ofatumumab versus ocrelizumab in multiple sclerosis. | Multiple sclerosis and related disorders |
| 2026-08-16 | PublicationGNE-related thrombocytopenia (Thrombocytopenia-12) in a 3-month-old from a Middle Eastern background infant: a case report. | Hematology (Amsterdam, Netherlands) |
| 2026-08-16 | PublicationCombined inhibition of complement C5 and neonatal Fc receptor in refractory generalized myasthenia gravis: A report of two cases. | Journal of neuroimmunology |
| 2026-08-16 | PublicationProteinuria selectivity index as a predictor of remission and rituximab efficacy in primary membranous nephropathy: a single-center retrospective analysis. | Renal failure |
| 2026-09-11 | Création de l’enregistrementNCT00000117 | Registre d’essai clinique |
| 2026-09-11 | PublicationFludarabine, Busulfan, Thiotepa, and Melphalan: A Novel Low-Toxicity Myeloablative Conditioning Regimen for Haploidentical HSCT in Children and Adolescents Aged ≥7 Years With Transfusion-Dependent β-Thalassemia. | Pediatric blood & cancer |
Début phase actuelle
Non disponible dans les sources synchronisées
Essais cliniques liés
1 essai(s)
Début phase actuelle
Non disponible dans les sources synchronisées
| NCT | Titre | Phase | Statut administratif | Pays | Sponsor |
|---|---|---|---|---|---|
| NCT00000117 | Intravenous Immunoglobulin Therapy in Optic Neuritis | Phase 3 | COMPLETED | United States | National Eye Institute (NEI) |
Publications liées
97 publication(s)Publications liées
97 publication(s)| Titre | PMID | DOI | Journal | Date |
|---|---|---|---|---|
| Fludarabine, Busulfan, Thiotepa, and Melphalan: A Novel Low-Toxicity Myeloablative Conditioning Regimen for Haploidentical HSCT in Children and Adolescents Aged ≥7 Years With Transfusion-Dependent β-Thalassemia. Voir source | 42489576 | 10.1002/1545-5017.70563 | Pediatric blood & cancer | |
| Effects of wildfire smoke exposure on health parameters and inflammatory responses of beef-on-dairy calves. Voir source | 41678211 | 10.1093/jas/skag040 | Journal of animal science | |
| Preclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseases. Voir source | 39559361 | 10.3389/fimmu.2024.1452537 | Frontiers in immunology | |
| Impact of antiviral treatment and initiation time on mother-to-child transmission in pregnant women with extremely high HBV DNA loads. Voir source | 42003011 | 10.1080/21505594.2026.2647479 | Virulence | |
| Clinical characteristics and diagnostic indicators of childhood-onset systemic lupus erythematosus complicated with macrophage activation syndrome. Voir source | 41824219 | 10.1007/s10067-026-08010-4 | Clinical rheumatology | |
| Patient perspectives on hemolytic disease of the fetus and newborn and fetal and neonatal alloimmune thrombocytopenia: common experiences and insights. Voir source | 42580888 | 10.1080/14767058.2026.2713843 | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians | |
| Analysis of the expression changes of IL-17+ γδ T cells and Treg cells in bone marrow mesenchymal stem cells targeted therapy for allergic rhinitis. Voir source | 33877651 | 10.26355/eurrev_202104_25539 | European review for medical and pharmacological sciences | |
| Anti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial. Voir source | 31582358 | 10.1016/S2213-2600(19)30253-X | The Lancet. Respiratory medicine | |
| A Comparative Real-World Study Evaluating the Safety of Immune Globulin Infusion (Human) 10% Solution and Other Intravenous Immunoglobulin Therapies for the Treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy. Voir source | 40095398 | 10.1002/pds.70124 | Pharmacoepidemiology and drug safety | |
| The Results of ADVANCE-CIDP IVIG Trial: Intravenous Immunoglobulin 10% Therapy With GAMMAGARD LIQUID/Kiovig for Treatment of Relapse in Chronic Inflammatory Demyelinating Polyradiculoneuropathy. Voir source | 40247653 | 10.1111/ene.70110 | European journal of neurology | |
| Clinical features, imaging findings, and treatment outcomes of optic neuritis associated with anti-CRMP5 antibodies: a systematic review. Voir source | 42372569 | 10.1016/j.jneuroim.2026.579015 | Journal of neuroimmunology | |
| Neuro-renal syndrome (NRS) in autoimmune nodopathies and paranodopathies: A warning to consider the diagnosis when anti-node and paranode antibody tests are difficult to perform. Voir source | 42497634 | 10.1016/j.jns.2026.126104 | Journal of the neurological sciences | |
| Risk factors for hypotension and technical complications during single-session double-filtration plasmapheresis: a 15-year retrospective study of 1,022 procedures. Voir source | 42226480 | 10.1080/0886022X.2026.2667592 | Renal failure | |
| The role of cardiac PET imaging in cardiac amyloidosis. Voir source | 42218056 | 10.1053/j.semnuclmed.2026.05.007 | Seminars in nuclear medicine | |
| Association of anti-glycolipid IgG with respiratory function decline in amyotrophic lateral sclerosis. Voir source | 42259179 | 10.1016/j.jns.2026.126039 | Journal of the neurological sciences | |
| Anti-GAD65 antibody-associated cerebellar ataxia in a young adult with type 1 diabetes: a case report and literature review. Voir source | 42582350 | 10.1007/s13340-026-00920-7 | Diabetology international | |
| The economic value of self-administered subcutaneous immunoglobulin G (SCIg) in Canada: a scoping review. Voir source | 41701183 | 10.1080/13696998.2026.2628450 | Journal of medical economics | |
| Results of a randomized double-blind placebo-controlled Phase 2 study propose iptacopan as an alternative complement pathway inhibitor for IgA nephropathy. Voir source | 37914086 | 10.1016/j.kint.2023.09.027 | Kidney international | |
| Nipocalimab and other FcRn blockers in neuromuscular disorders. Voir source | 42398839 | 10.1016/j.pharmthera.2026.109071 | Pharmacology & therapeutics | |
| Effect of nipocalimab on IgG responses to vaccinations and viral infections in patients with IgG autoantibody-mediated diseases: Post hoc analyses of three randomized, placebo-controlled trials. Voir source | 42084498 | 10.1080/21645515.2026.2664331 | Human vaccines & immunotherapeutics | |
| Corticosteroids and mycophenolic acid analogues in immunoglobulin A nephropathy with progressive decline in kidney function. Voir source | 35371455 | 10.1093/ckj/sfab244 | Clinical kidney journal | |
| Shared genetics of IgA nephropathy and cardiometabolic diseases revealed by integrative genomic analysis. Voir source | 42535737 | 10.1080/0886022X.2026.2706884 | Renal failure | |
| Efficacy and Safety of Subcutaneous Belimumab in Anti-Double-Stranded DNA-Positive, Hypocomplementemic Patients With Systemic Lupus Erythematosus. Voir source | 29671280 | 10.1002/art.40511 | Arthritis & rheumatology (Hoboken, N.J.) | |
| Protein L: a novel reagent for the detection of chimeric antigen receptor (CAR) expression by flow cytometry. Voir source | 22330761 | 10.1186/1479-5876-10-29 | Journal of translational medicine | |
| Resolution of Neuroblastoma-Related Opsoclonus-Myoclonus Ataxia Syndrome Following Tandem High-Dose Chemotherapy With Autologous Hematopoietic Stem Cell Transplantation and Extensive Intravenous Immunoglobulin. Voir source | 42569906 | 10.1002/1545-5017.70619 | Pediatric blood & cancer | |
| Vitreoretinal Lymphoma: A Comprehensive Clinical Review and Current Standards in Management. Voir source | 42602195 | 10.1177/24741264261474159 | Journal of vitreoretinal diseases | |
| Proliferative glomerulonephritis with monoclonal IgG3 deposits: A case series. Voir source | 42519182 | 10.1016/j.jtauto.2026.100385 | Journal of translational autoimmunity | |
| A case of drug-induced bullous pemphigoid secondary to immunotherapy treated with upadacitinib: A case report. Voir source | 36968984 | 10.1177/2050313X231160926 | SAGE open medical case reports | |
| Ofatumumab Treatment Used in Pediatric MOGAD: A Retrospective Case Series. Voir source | 41971752 | 10.1177/11795735261436889 | Journal of central nervous system disease | |
| Intravenous immunotherapy with Der p 1-containing nanoparticles alleviates the allergic responses in a murine allergic rhinitis model. Voir source | 41805230 | 10.1080/21645515.2026.2612810 | Human vaccines & immunotherapeutics | |
| type B (Hib) necrotizing soft tissue infection (NSTI) in a vaccinated 16-month-old Inuit boy: a case report. Voir source | 42446531 | 10.1080/22423982.2026.2702788 | International journal of circumpolar health | |
| A multiple ascending dose, phase1b study to evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of lesigercept, a long-acting IgE-Fc fusion protein, in participants with atopy or allergic diseases. Voir source | 42594832 | 10.1016/j.intimp.2026.117275 | International immunopharmacology | |
| Successful treatment of pure red cell aplasia with Orelabrutinib following major ABO-incompatible hematopoietic stem cell transplantation for acute myeloid leukemia: A case report. Voir source | 42385585 | 10.1016/j.transci.2026.104478 | Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis | |
| Immunoglobulin dynamics and infection risk with ofatumumab versus ocrelizumab in multiple sclerosis. Voir source | 42413316 | 10.1016/j.msard.2026.107373 | Multiple sclerosis and related disorders | |
| GNE-related thrombocytopenia (Thrombocytopenia-12) in a 3-month-old from a Middle Eastern background infant: a case report. Voir source | 41622814 | 10.1080/16078454.2026.2620148 | Hematology (Amsterdam, Netherlands) | |
| Combined inhibition of complement C5 and neonatal Fc receptor in refractory generalized myasthenia gravis: A report of two cases. Voir source | 42030590 | 10.1016/j.jneuroim.2026.578944 | Journal of neuroimmunology | |
| Proteinuria selectivity index as a predictor of remission and rituximab efficacy in primary membranous nephropathy: a single-center retrospective analysis. Voir source | 42535733 | 10.1080/0886022X.2026.2683746 | Renal failure | |
| Transient Neonatal Myasthenia Gravis in a Newborn Infant Presenting to an Emergency Department. Voir source | 42583073 | 10.7759/cureus.112517 | Cureus | |
| When Neurodevelopment Meets Autoimmunity: Pemphigus Foliaceus in Rett Syndrome Expands the Clinical Spectrum-A Case Report. Voir source | 42589518 | 10.3390/ijms27156862 | International journal of molecular sciences | |
| New and Emerging Nonimmunosuppressive Drug Therapies for Primary Adult Glomerular Diseases. Voir source | 42165056 | 10.1016/j.xkme.2025.101133 | Kidney medicine | |
| Obinutuzumab β for aquaporin-4-positive neuromyelitis optica spectrum disorder: a phase 3 randomized controlled trial. Voir source | 42575985 | 10.1038/s41591-026-04583-4 | Nature medicine | |
| Management of Exacerbations and Rescue Therapy: A Prespecified Analysis of the Phase 3 Myasthenia Gravis Inebilizumab Randomized Clinical Trial. Voir source | 42573995 | 10.1001/jamaneurol.2026.2558 | JAMA neurology | |
| Urticaria as a dermatologic manifestation of Giardia infection: a systematic review of clinical, diagnostic, and therapeutic features. Voir source | 40890603 | 10.1186/s12879-025-11484-3 | BMC infectious diseases | |
| Efficacy and safety of emerging immunomodulatory agents versus standard therapies in refractory cutaneous lupus: A systematic review. Voir source | 42522483 | 10.25251/52gar039 | Dermatology online journal | |
| BK Polyomavirus-Associated Nephropathy Complicated by Life-Threatening Hemorrhagic Pericardial Effusion Following Immunosuppression Reduction in a Kidney Transplant Recipient: A Case Report. Voir source | 42529343 | 10.1155/crit/2999849 | Case reports in transplantation | |
| Formation and preliminary characterization of mercury-reactive immunoglobulin Y antibodies in laying hens using HgCl-protein hapten conjugates. Voir source | 42494697 | 10.14202/vetworld.2026.2597-2605 | Veterinary world | |
| Immunotherapy Resistance in dMMR/MSI-H Colorectal Cancer: Unraveling Mechanisms and Exploring Overcoming Strategies. Voir source | 42590903 | 10.1155/jimr/5084171 | Journal of immunology research | |
| Immunoglobulin Superfamily Protein BTNL9 Functions as a Non-Canonical Transcriptional Regulator to Suppress NSCLC Through Cell Cycle and p53 Pathways. Voir source | 42589257 | 10.3390/ijms27156598 | International journal of molecular sciences | |
| Case Report of Combined Central and Peripheral Demyelination: Treated With Ofatumumab. Voir source | 42207162 | 10.1002/iid3.70459 | Immunity, inflammation and disease | |
| Probable Autoimmune Encephalitis Presenting With Catatonia in a Young Woman: A Case Report and Review of the Literature. Voir source | 40952037 | 10.1177/00912174251380668 | International journal of psychiatry in medicine | |
| AQP4-IgG-positive myelitis occurring in a patient with small cell lung cancer: a case report. Voir source | 42591078 | 10.3389/fonc.2026.1867559 | Frontiers in oncology | |
| Immune thrombocytopenia: Evolving mechanistic understanding and clinical development of new therapies. Voir source | 42453522 | 10.4103/tcmj.TCMJ-D-25-00206 | Tzu chi medical journal | |
| Eculizumab treatment in the salvage therapy of MOGAD: a case report. Voir source | 42577385 | 10.3389/fimmu.2026.1861880 | Frontiers in immunology | |
| Concurrent herpetic hypertensive anterior uveitis and cytomegalovirus retinitis in a non-HIV patient with melanoma differentiation-associated gene-5 dermatomyositis: intravenous immunoglobulin comes to the rescue. Voir source | 42017386 | 10.4081/reumatismo.2026.1826 | Reumatismo | |
| Abdominal Wall Erythema as a Suspected Extracardiac Manifestation of Cardiac Allograft Rejection. Voir source | 42564926 | 10.7759/cureus.112218 | Cureus | |
| Safety and tolerability of a new intravenous immunoglobulin 10% in patients with primary immunodeficiency. Voir source | 42565276 | 10.1080/1750743X.2026.2706964 | Immunotherapy | |
| Effects of the active amyloid beta immunotherapy CAD106 on PET measurements of amyloid plaque deposition in cognitively unimpaired APOE ε4 homozygotes. Voir source | 38145469 | 10.1002/alz.13532 | Alzheimer's & dementia : the journal of the Alzheimer's Association | |
| Ultrasound-Guided Stellate Ganglion and Interscalene Blocks for Refractory Pediatric Parsonage-Turner Syndrome: A Case Report and Clinical Implications. Voir source | 42550561 | Pain medicine case reports | ||
| Paroxysmal Speech Arrest With Resolving Splenial and Symmetric White Matter Lesions in a Child: A Case Report. Voir source | 42564878 | 10.7759/cureus.113992 | Cureus | |
| Acute Attack Treatment Escalation and Subsequent Relapse Risk in Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. Voir source | 42566724 | 10.1212/WNL.0000000000218405 | Neurology | |
| Differential safety profiles of disease-modifying therapies in MS: Age- and sex-based analysis from a real-world cohort. Voir source | 42107470 | 10.1016/j.msard.2026.107220 | Multiple sclerosis and related disorders | |
| Lymphoplasmapheresis for Refractory Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report. Voir source | 42503002 | 10.1002/jca.70157 | Journal of clinical apheresis | |
| A High-dose Pharmacokinetic Study of a New IgG4 Monoclonal Antibody Temelimab/GNbAC1 Antagonist of an Endogenous Retroviral Protein pHERV-W Env. Voir source | 31311668 | 10.1016/j.clinthera.2019.05.020 | Clinical therapeutics | |
| Immunoglobulin G4-Related Sclerosing Cholangitis: A Review. Voir source | 42486600 | 10.1016/j.cld.2026.04.004 | Clinics in liver disease | |
| Evaluation of the humoral response during ocrelizumab therapy in multiple sclerosis - an observational study. Voir source | 42478450 | 10.5603/pjnns.108289 | Neurologia i neurochirurgia polska | |
| Telitacicept, a novel humanized, recombinant TACI-Fc fusion protein, for the treatment of systemic lupus erythematosus. Voir source | 35107091 | 10.1358/dot.2022.58.1.3352743 | Drugs of today (Barcelona, Spain : 1998) | |
| Guillain-Barré syndrome with bilateral extensor plantar responses: A rare case report. Voir source | 42483360 | 10.4103/jfmpc.jfmpc_2009_25 | Journal of family medicine and primary care | |
| Case Report: Hereditary thrombotic thrombocytopenic purpura mimicking immune thrombocytopenia: diagnostic pitfalls of whole-exome sequencing. Voir source | 42483413 | 10.3389/fped.2026.1875502 | Frontiers in pediatrics | |
| Integrating Cerebrospinal Fluid Metagenomic Next-Generation Sequencing and Immune Profiling in Recurrent HSV-1 Encephalitis: A Case Report and Narrative Review. Voir source | 42484489 | 10.1177/08830738261465526 | Journal of child neurology | |
| Povetacicept (ALPN-303; TACI vTD-Fc), an enhanced, potent dual inhibitor of BAFF and APRIL, ameliorates experimental autoimmune myasthenia gravis in C57BL/6N mice. Voir source | 40547042 | 10.3389/fimmu.2025.1533093 | Frontiers in immunology | |
| A case report of Good syndrome: Diarrhea and dyspnea. Voir source | 42470030 | 10.1097/MD.0000000000049404 | Medicine | |
| Knowledge graph visualization and bibliometric analysis of research on coronary artery lesions in Kawasaki disease. Voir source | 42470076 | 10.1097/MD.0000000000049678 | Medicine | |
| Immunological Dynamics and Outcomes of ABO-Incompatible Kidney Transplants: Insights From a 5+-Year Follow-Up at a Transplant-Heavy Tertiary Center in Saudi Arabia. Voir source | 42403973 | 10.1155/joot/6265955 | Journal of transplantation | |
| 36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016. Voir source | 27885969 | 10.1186/s13054-016-1208-6 | Critical care (London, England) | |
| Alleviation effect of Potentilla anserina polysaccharides on intestinal barrier dysfunction and its underlying mechanism. Voir source | 42448191 | 10.1016/j.ijbiomac.2026.153526 | International journal of biological macromolecules | |
| Case of concurrent ALS and human T-cell leukaemia virus type 1-associated myositis. Voir source | 42414029 | 10.1136/bcr-2025-270944 | BMJ case reports | |
| Case Report: Stevens-Johnson syndrome/toxic epidermal necrolysis overlap with ocular and urogenital involvement in an extremely preterm infant following broad-spectrum antibiotic exposure. Voir source | 42440440 | 10.3389/fmed.2026.1854901 | Frontiers in medicine | |
| Real-world experience with switching from intravenous immunoglobulin to subcutaneous efgartigimod PH20 in patients with chronic inflammatory demyelinating polyradiculoneuropathy: A case series. Voir source | 41950575 | 10.1016/j.jneuroim.2026.578925 | Journal of neuroimmunology | |
| Fulminant paraneoplastic Ma2 (PNMA2) and zinc finger protein of the cerebellum 4 (ZIC4) antibody-positive encephalitis in triple-negative breast cancer treated with pembrolizumab. Voir source | 42442848 | 10.1136/bcr-2025-269510 | BMJ case reports | |
| Randomized Double-Blind Placebo-Controlled Trial of the Corticosteroid-Sparing Effects of Immunoglobulin in Myasthenia Gravis. Voir source | 36270895 | 10.1212/WNL.0000000000201501 | Neurology | |
| Efficacy and safety of maintenance intravenous immunoglobulin in generalized myasthenia gravis patients with acetylcholine receptor antibodies: A multicenter, double-blind, placebo-controlled trial. Voir source | 39506903 | 10.1002/mus.28289 | Muscle & nerve | |
| Intravenous Immunoglobulin-Resistant Kawasaki Disease: Diagnosis, Mechanisms, and Clinical Management. Voir source | 42442680 | 10.1016/j.ejphar.2026.179135 | European journal of pharmacology | |
| Peripheral blood immunoglobulin A level is independently negatively correlated with renal involvement in newly diagnosed childhood systemic lupus erythematosus: a single-center cross-sectional study based on 380 pediatric lupus nephritis patients in southwest China. Voir source | 42440243 | 10.1007/s10067-026-08267-9 | Clinical rheumatology | |
| Purpura as the initial manifestation of IgG4-related disease with concomitant systemic lupus erythematosus: a case report. Voir source | 42440567 | 10.3389/fmed.2026.1872392 | Frontiers in medicine | |
| Fulminant toxic epidermal necrolysis induced by pucotenlimab in a patient with lung adenocarcinoma: a case report. Voir source | 42434740 | 10.3389/fonc.2026.1790323 | Frontiers in oncology | |
| Guillain-Barré Syndrome Following Dengue Infection: A Case Series with Review of Literature. Voir source | 42436651 | 10.1177/09727531261457213 | Annals of neurosciences | |
| Chorea as a Non-Thrombotic Manifestation in an Adolescent with Systemic Lupus Erythematosus, Antiphospholipid Syndrome and Heterozygous Prothrombin G20210A Gene Mutation: A Case Report. Voir source | 42428154 | 10.1159/000552585 | Case reports in neurology | |
| Novel pathological genetic variant associated with DOCK8 deficiency: case report with successful hematopoietic stem cell transplantation. Voir source | 42433063 | 10.15586/aei.v54i4.1585 | Allergologia et immunopathologia | |
| Precision myeloablation with TDM-guided busulfan in pediatric primary immunodeficiencies: a real-world study of 28 patients. Voir source | 42433921 | 10.21037/tp-2026-0344 | Translational pediatrics | |
| Nasal Manifestations of Immunoglobulin A (IgA) Vasculitis in an Adolescent Patient: A Case Report. Voir source | 42434625 | 10.7759/cureus.110592 | Cureus | |
| Antimetabolites synergize with non-genotoxic antibody drug conjugate conditioning in hematopoietic stem cell lentiviral gene therapy. Voir source | 42436858 | 10.1016/j.omta.2026.201780 | Molecular therapy. Advances | |
| West Nile Neuroinvasive Disease: Current Management, Emerging Therapies and Future Clinical Trial Priorities. Voir source | 42431607 | 10.1002/rmv.70182 | Reviews in medical virology | |
| Pridopidine Protects ALS Patient-Derived Neural Progenitor Cells via Sigma-1 Receptor Activation. Voir source | 42074133 | 10.3390/ijms27083489 | International journal of molecular sciences | |
| [Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits (PGNMID) Associated with Marginal Zone B-cell Lymphoma: A Case of MGRS in a Patient with Nephrotic Syndrome and Rapidly Progressive Renal Failure]. Voir source | 42423062 | 10.69097/43-03-2026-10 | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia | |
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| Adjuvant intravenous immunoglobulin in elderly sepsis: a randomized controlled study of mortality, organ function, and inflammation. Voir source | 42422830 | 10.3389/fmed.2026.1857404 | Frontiers in medicine | |
| Steroid-Sparing Effect of Efgartigimod in Generalized Myasthenia Gravis: Study Protocol for a Single-Arm, Open-Label Clinical Trial. Voir source | 42371330 | 10.1007/s40120-026-00980-6 | Neurology and therapy |
Sources officielles
liens de rechercheDernière mise à jour des données : 2009-09-16
Ces sources sont proposées pour vérification. Les informations de la fiche doivent être confirmées dans les registres officiels ou les publications originales.