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Synchronisé depuis ClinicalTrials.gov — NCT04745299

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Essais cliniques associés

30
MoléculeIndication / populationPhaseNCTTitreStatut
Giredestrant Cancer Phase 3 NCT06065748 A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer) ACTIVE_NOT_RECRUITING
Zanidatamab Cancer Phase 3 NCT06282575 Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer RECRUITING
RO7126209 Alzheimer Phase 1/2 NCT04639050 Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease ACTIVE_NOT_RECRUITING
Sotorasib Cancer Phase 3 NCT05920356 A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) RECRUITING
Obinutuzumab Cancer Phase 3 NCT06084936 GLOBRYTE — A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma RECRUITING
Inavolisib Cancer Phase 3 NCT06790693 INAVO123 — A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer RECRUITING
Inavolisib Cancer Phase 2 NCT07054190 A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer RECRUITING
Amivantamab Cancer Phase 3 NCT04538664 PAPILLON — A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions ACTIVE_NOT_RECRUITING
ACP-204 Alzheimer Phase 2/3 NCT06159673 ACP-204 in Adults With Alzheimer's Disease Psychosis RECRUITING
KarXT Alzheimer Phase 3 NCT06585787 A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4) RECRUITING
Home-Based Tele-Rehabilitation for Respiratory Function in Children With Duchenne Muscular Dystrophy Myopathies Non applicable NCT07629284 Home-Based Tele-Rehabilitation for Respiratory Function in Children With Duchenne Muscular Dystrophy ENROLLING_BY_INVITATION
PF-06821497 Cancer Phase 3 NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer. RECRUITING
Elranatamab Cancer Phase 3 NCT06152575 MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide) RECRUITING
DKF-MA102 Cancer Phase 3 NCT06490328 Efficacy and Safety of DKF-MA102 in Patients With Prostate Cancer COMPLETED
Precemtabart tocentecan Cancer Phase 3 NCT07549412 A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03) RECRUITING
Lenzumestrocel Sclérose latérale amyotrophique Phase 3 NCT04745299 ALSummit — Evaluation the Efficacy and Safety of Mutiple Lenzumestrocel (Neuronata-R® Inj.) Treatment in Patients With ALS COMPLETED
Acoramidis Alzheimer Phase 3 NCT06563895 Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant RECRUITING
ACP-204 Alzheimer Phase 3 NCT06194799 ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study ENROLLING_BY_INVITATION
Trontinemab Alzheimer Phase 3 NCT07170150 TRONTIER 2 — A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease RECRUITING
Prasinezumab Parkinson Phase 3 NCT07174310 PARAISO — A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease RECRUITING
Pozelimab + Cemdisiran Myasthénie Phase 3 NCT05070858 NIMBLE — A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis ACTIVE_NOT_RECRUITING
Cladribine Low Dose Myasthénie Phase 3 NCT06463587 Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad) RECRUITING
PF-06939926 Myopathies Phase 3 NCT04281485 Study to Evaluate the Safety and Efficacy of PF-06939926 for the Treatment of Duchenne Muscular Dystrophy ACTIVE_NOT_RECRUITING
DYNE-251 Myopathies Phase 1/2 NCT05524883 DELIVER — Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping ACTIVE_NOT_RECRUITING
Vonsetamig Lupus Phase 1 NCT06975787 Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis RECRUITING
Vutiglabridin Alzheimer Phase 2 NCT06329141 A Study to Assess the Efficacy and Safety of Vutiglabridin in Early Parkinson's Disease Patients COMPLETED
Deep Brain Stimulation (DBS) Parkinson À vérifier NCT02071134 Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry RECRUITING
MT-1186 Sclérose latérale amyotrophique Phase 3 NCT04569084 Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS TERMINATED
Sacituzumab govitecan-hziy Cancer Phase 3 NCT06486441 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26) ACTIVE_NOT_RECRUITING
Fenebrutinib SEP Phase 3 NCT04586023 FENhance 2 — Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS) ACTIVE_NOT_RECRUITING