Vue transversale de la maladie
Hypertension artérielle
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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525 résultats correspondants
· 47 visibles sur cette page
dans le périmètre Hypertension artérielle
Niveau clinique
Études et traitements 217
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Understanding the Pathophysiology of Migraine Pain NCT03026101 · NCT03026101 | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | TERMINATED | Migraine is the most common headache disorder, prevalent in 18% of females… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Comparator Nifedipine 30 mg Extended-Release Étude non communiquée | Hypertension artérielle | À vérifier | Phase 3 | Terminé | To evaluate the efficacy of Nifedipine 30mg Extended-Release Richmond vers… À vérifier | ClinicalTrials.gov 2026-08-11 | Détail |
| Anti-hypertensive therapy NCT02299414 · Chronic Hypertension and Pregnancy (CHAP) Project | Hypertension artérielle | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to evaluate whether a blood pressure treatmen… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Carotid body excision NCT01729988 · Carotid Body Removal for the Treatment of Resistant Hypertension: a Pilot Study | Hypertension artérielle | À vérifier | NA | COMPLETED | This is a pilot study to assess the effectiveness, safety and feasibility… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Community Vital Signs (CVS): An Integrated Community-Based Approach t… NCT06659900 · NCT06659900 | Hypertension artérielle | À vérifier | NA | ENROLLING_BY_INVITATION | If detected early, hypertension (HTN) is treatable; yet, HTN screening rat… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Darbepoetin NCT03810911 · EPIC — Mechanisms of EPO-induced Hypertension | Hypertension artérielle | À vérifier | Phase 2 | TERMINATED | The investigators hypothesize that compared to untreated controls, erythro… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Impact of Consumption of Beta-glucans on the Intestinal Microbiota an… NCT02041104 · NCT02041104 | Hypertension artérielle | À vérifier | NA | COMPLETED | The purpose of this study is to investigate if daily consumption of barley… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Osilodrostat NCT07247162 · LINC CARE — Osilodrostat in Patients With Hypertension Caused by Hypercortisolae… | Hypertension artérielle | À vérifier | Phase 4 | NOT_YET_RECRUITING | Osilodrostat has proven to be a safe and efficacious treatment for patient… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Relaxation Response Training to Treat Hypertension NCT01263743 · NCT01263743 | Hypertension artérielle | Traitement symptomatique | NA | COMPLETED | Interventions such as Relaxation Response appear to have widespread effect… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Renal denervation NCT04722159 · Clinical Outcome of Patients With Resistant Hypertension Undergoing Renal Denerv… | Hypertension artérielle | À vérifier | À vérifier | UNKNOWN | Recent clinical studies have demonstrated that catheter-based renal sympat… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Selective vagus nerve stimulation NCT00983632 · VNS — Selective Vagus Nerve Stimulation in Human | Hypertension artérielle | À vérifier | NA | COMPLETED | The investigators would like to explore possibilities of selective vagus n… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| The Efficacy, Safety and Genetic Polymorphism of Hypoca and Adalat OR… NCT00728858 · NCT00728858 | Hypertension artérielle | À vérifier | À vérifier | COMPLETED | Nifedipine and barnidipine act as calcium channel blockers, and are widely… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| uAOBP NCT03578848 · GYMNs — Guiding Hypertension Management Using Different Blood Pressure Monitorin… | Hypertension artérielle | À vérifier | NA | UNKNOWN | Patients with uncontrolled or newly diagnosed hypertension will be randomi… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Veterans Service Organizations and My HealtheVet (MHV) NCT01597843 · NCT01597843 | Hypertension artérielle | À vérifier | NA | COMPLETED | This project will design, deliver, and evaluate a peer support interventio… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| Women's-Beet — Nitrate, Exercise and Vascular Function in Midlife Wom… NCT06527248 · NCT06527248 | Hypertension artérielle | Neuroprotection · Immunomodulation | NA | RECRUITING | The purpose of this clinical study in women after menopause is to investig… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:19 | Détail |
| BR1019 NCT06226727 · A Study to Evaluate the Pharmacokinetics and the Safety After Administration of… | Hypertension artérielle | À vérifier | Phase 1 | COMPLETED | The objective of this clinical study is to evaluate the pharmacokinetics a… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:05 | Détail |
| CONSULT-BP — COmmuNity-engaged SimULation Training for Blood Pressure… NCT03375918 · NCT03375918 | Hypertension artérielle | À vérifier | NA | COMPLETED | The goal of CONSULT-BP is to train early-stage healthcare providers, inclu… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:05 | Détail |
| Diabetes and Hypertension Self Management Program NCT06034548 · NCT06034548 | Hypertension artérielle | À vérifier | NA | COMPLETED | The purpose of this R15 project is to test the feasibility and effectivene… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:05 | Détail |
| Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Fact… NCT00666250 · NCT00666250 | Hypertension artérielle | À vérifier | NA | COMPLETED | An antioxidant dietary supplement made from cocoa powder, and extracts of… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:05 | Détail |
| Fimasartan/Amlodipine NCT02920047 · A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Fimasartan and A… | Hypertension artérielle | À vérifier | Phase 1 | COMPLETED | The purpose of this study is to evaluate the pharmacokinetics and safety w… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:05 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 301
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| A Randomized Feasibility Trial of a Multicomponent Quality Improvemen… Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control ·… | Hypertension artérielle | Ralentissement de la progression | Publication | PubMed | Voir la publication source Chronic cardiovascular diseases (CVD) care quality remains suboptimal, globally. This study evaluated the feasibility a… | medRxiv : the preprint server for health sciences 2026-08-16 13:13:58 | Source |
| Frontiers of cardiovascular polypills: From atherosclerosis and beyon… Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control ·… | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Fixed-dose combination (FDC) therapies (also known as polypills) remain underutilized in clinical practice despite over… | Trends in cardiovascular medicine 2026-08-16 13:13:58 | Source |
| Evaluation of Polygenic Scores and CT Imaging in Risk Factor Modifica… Nurse-Led Motivational Interviewing for Blood Pressure Control · PMID 42223325 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The contemporary management of type 2 diabetes (T2D) involves a multifaceted model of care integrating intensive manage… | Clinical cardiology 2026-08-16 13:13:53 | Source |
| Cardiometabolic benefits of parathyroidectomy in dialysis patients wi… OCORO — Study of the Progression of Chronic Cardiovascular Conditions · PMID 42338091 | Hypertension artérielle | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Secondary hyperparathyroidism (SHPT) contributes to mineral-bone disorders, chronic inflammation, and adverse cardiomet… | Renal failure 2026-08-16 13:13:50 | Source |
| Pentoxifylline and cardiorenal outcomes in advanced CKD with untreate… OCORO — Study of the Progression of Chronic Cardiovascular Conditions · PMID 42393494 | Hypertension artérielle | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Patients with advanced chronic kidney disease (CKD) and dyslipidemia are at high risk of kidney failure and cardiovascu… | Renal failure 2026-08-16 13:13:50 | Source |
| The impact of multiple long-term conditions on mortality, progression… OCORO — Study of the Progression of Chronic Cardiovascular Conditions · PMID 42334309 | Hypertension artérielle | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Multiple long-term conditions (MLTC) are common in people with chronic kidney disease (CKD). This study examined the im… | Annals of medicine 2026-08-16 13:13:50 | Source |
| Exploring Interprofessional Primary Care (IPPC) teams' impact on chro… Team-based shared decision-making · PMID 42542561 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Interprofessional care involves two or more professionals from different disciplines working in partnership to achieve… | Journal of interprofessional care 2026-08-16 13:13:49 | Source |
| Interprofessional education in pharmacy: Bridging collaborative compe… Team-based shared decision-making · PMID 42019190 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Interprofessional education (IPE) has been widely adopted in pharmacy education to enhance collaborative competencies a… | Currents in pharmacy teaching & learning 2026-08-16 13:13:49 | Source |
| Rethinking obesity management targets: Findings from an international… Team-based shared decision-making · PMID 42602889 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Obesity is a chronic disease that requires individualized, person-centred care beyond traditional weight-centric target… | Obesity pillars 2026-08-16 13:13:49 | Source |
| Feasibility and Acceptability of a Novel Algorithm for Physicians to… P3-EX — A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiov… | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Approximately half of U.S. adults have ≥1 cardiovascular disease (CVD) risk factors. Exercise is universally recommende… | Healthcare (Basel, Switzerland) 2026-08-16 13:13:46 | Source |
| Digital Health Monitoring and Intervention Suite for Stress in Frontl… Assessing the Feasibility of the "Heart Care Pairs" Intervention · PMID 42275639 | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source Stress among health care workers (HCWs) contributes to burnout, workforce attrition, and adverse patient outcomes. Alth… | JMIR formative research 2026-08-16 13:13:44 | Source |
| Feasibility and preliminary efficacy of a 12-week primary care-based… Assessing the Feasibility of the "Heart Care Pairs" Intervention · PMID 41851425 | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source Physical activity (PA) and dietary counseling are recommended for adults with cardiovascular disease (CVD) risk factors… | Journal of behavioral medicine 2026-08-16 13:13:44 | Source |
| Frailty Status and Outcomes in Patients with Acute Coronary Syndrome… Assessing the Feasibility of the "Heart Care Pairs" Intervention · PMID 42411588 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Frailty is increasingly recognised as an age-independent predictor of adverse outcomes in cardiovascular disease, yet i… | European journal of cardiovascular nursing 2026-08-16 13:13:44 | Source |
| Home blood pressure-guided antihypertensive therapy in chronic kidney… Conventional office blood pressure-guided management · PMID 29459219 | Hypertension artérielle | Ralentissement de la progression | Publication | PubMed | Voir la publication source In the era of newly introduced hypertension guidelines recommending lower blood pressure (BP) targets for drug-treated… | Journal of the American Society of Hypertension : JASH 2026-08-16 13:13:42 | Source |
| A randomized controlled trial comparing the efficacy of nifedipine an… Comparator Nifedipine 30 mg Extended-Release · PMID 37806651 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Postpartum hypertension is a common medical complication of pregnancy and is associated with increased healthcare use,… | American journal of obstetrics & gynecology MFM 2026-08-16 13:13:35 | Source |
| Comparative efficacy of generic nifedipine versus brand-name amlodipi… Comparator Nifedipine 30 mg Extended-Release · PMID 35674192 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The control rate of hypertension remains concerning, indicating the requirement for better management strategies. The c… | Journal of clinical hypertension (Greenwich, Conn.) 2026-08-16 13:13:35 | Source |
| Trial of Intrapartum Extended-Release Nifedipine to Prevent Severe Hy… Comparator Nifedipine 30 mg Extended-Release · PMID 36189646 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Preeclampsia is associated with maternal and perinatal morbidity. Besides acute therapy for severe hypertension, best p… | Hypertension (Dallas, Tex. : 1979) 2026-08-16 13:13:35 | Source |
| Causal relationship between epigenetic markers and type 2 diabetes in… Genetics of Type 2 Diabetes in West Africans · PMID 42032377 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Evidence for a causal role of DNA methylation sites (CpGs) in type 2 diabetes and glycaemic traits is limited due to th… | Diabetologia 2026-08-16 13:13:31 | Source |
| Epigenome-wide analysis in West Africans identifies DNA methylation m… Genetics of Type 2 Diabetes in West Africans · PMID 41793944 | Hypertension artérielle | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Adiponectin is a circulating adipokine involved in energy metabolism and inflammation, with reported protective effects… | EBioMedicine 2026-08-16 13:13:31 | Source |
| Integration of clinical and proteomic risk factors enhances prognosti… Genetics of Type 2 Diabetes in West Africans · PMID 41559749 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source BACKGROUND: Type 2 diabetes complications manifest across various organs, but are fundamentally rooted in vascular dysf… | Cardiovascular diabetology 2026-08-16 13:13:31 | Source |
Exploration — prudence
Pistes exploratoires 7
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Hypertension artérielle | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Hypert… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Hypertension artérielle | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Bavisant BRAVEinMS — Bavisant | Hypertension artérielle | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Hyper… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Hypertension artérielle | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Hyper… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Hypertension artérielle | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Hyperte… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Hypertension artérielle | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Hypertension artérielle | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |