Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1012 résultats correspondants
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dans le périmètre Myopathies
Niveau clinique
Études et traitements 421
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Transcutaneous Spinal Stimulation (TSS) NCT05429736 · Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spa… | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | For many people with spinal cord injury (SCI), the goal of walking is a hi… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:33 | Détail |
| AZD0530 Difumarate NCT04307953 · STOPFOP — Saracatinib Trial TO Prevent FOP | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | This is a phase 2 study, designed as a European multicentre 6-month double… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| CABA-201 following preconditioning with fludarabine and cyclophospham… NCT06154252 · RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-… | Myopathies | Immunomodulation | Phase 2/3 | RECRUITING | RESET-Myositis: Open-Label Study to Evaluate the Safety and Efficacy of CA… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Clinical evaluation NCT07792421 · NAP SAPS CSI — Pain Phenotype and Response to Corticosteroid Injection in Patien… | Myopathies | Traitement symptomatique | À vérifier | NOT_YET_RECRUITING | The goal of this prospective cohort study is to investigate whether pain p… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Clinical evaluation NCT07792434 · The NAP SAPS — Nociplastic Pain in Patients Diagnosed With Subacromial Pain Synd… | Myopathies | Traitement symptomatique | À vérifier | NOT_YET_RECRUITING | The goal of this prospective cohort study is to investigate whether pain p… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Effectiveness of Brief Mindfulness-Based Interventions for Painful Te… NCT06582134 · NCT06582134 | Myopathies | Traitement symptomatique · Thérapie génique | Non applicable | COMPLETED | The goal of this clinical trial is to learn if brief mindfulness-based int… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| End-expiratory Transpulmonary Pressure-guided vs Electrical Impedance… NCT06697717 · End-expiratory Transpulmonary Pressure-guided vs Electrical Impedance Tomography… | Myopathies | À vérifier | Non applicable | COMPLETED | This study aims to adopt a randomized crossover design to compare the effe… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| GRASP-01-002 — Defining Endpoints in Becker Muscular Dystrophy NCT05257473 · NCT05257473 | Myopathies | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | This is a 24-month, observational study of 50 participants with Becker mus… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| INIT ART — Comparison of Integrated Neuromuscular Inhibition Techniqu… NCT07395154 · NCT07395154 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | The goal of this clinical trial is to determine whether two manual therapy… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Monoplace Hyperbaric Chamber (Class III medical device). NCT06082518 · PCS-HBOT — Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | Over 500 million people have been infected with COVID-19, and to date, mor… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Piloting a Novel Peer Support Pain Self-Management Intervention (Proj… NCT04229134 · NCT04229134 | Myopathies | Traitement symptomatique · Thérapie génique | Non applicable | COMPLETED | The proposed study will test the feasibility and acceptability of an 8-wee… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Pulsed Electromagnetic Field Therapy NCT07802938 · Pulsed Electromagnetic Field Therapy Added to ESWT for Lateral Epicondylitis | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized, sham-controlled, assessor-blinded clinical trial will eva… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Resamirigene bilparvovec NCT03199469 · ASPIRO — A Study of AT132 in Young Children With X-Linked Myotubular Myopathy (X… | Myopathies | Traitement symptomatique · Thérapie génique | Phase 2/3 | ACTIVE_NOT_RECRUITING | X-linked myotubular myopathy (XLMTM) is a rare and serious condition prese… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| SFL-0821 for injection NCT07798609 · A Trial to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and… | Myopathies | À vérifier | Phase 1/2 | NOT_YET_RECRUITING | The purpose of this study is to evaluate the safety, tolerability, and pre… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Triamcinolone injection to the shoulder, elbow, wrist, or hand NCT05292339 · Ketorolac in Upper Extremity Tendinopathy and Arthropathy | Myopathies | Immunomodulation · Traitement symptomatique | Phase 4 | RECRUITING | Osteoarthritis (OA) and inflammatory conditions of the tendons and joints… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| UX016 NCT07511556 · First-in-human Study of UX016 in GNEM | Myopathies | À vérifier | Phase 1/2 | RECRUITING | The goal of this study is to assess the safety and dose of UX016 and its i… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Whole body vibration therapy NCT07286435 · The Effect of Whole-Body Vibration Therapy Following Botulinum Toxin A Injection… | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The purpose of this clinical study is to evaluate the effect of Whole Body… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| zeleciment basivarsen (DYNE-101) NCT07486934 · Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Partic… | Myopathies | À vérifier | Phase 3 | RECRUITING | The purpose of the study is to assess the efficacy, safety, and tolerabili… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Sham whole body vibration therapy Étude non communiquée | Myopathies | Traitement symptomatique | Non applicable | Actif | The purpose of this clinical study is to evaluate the effect of Whole Body… À vérifier | ClinicalTrials.gov 2026-09-02 | Détail |
| Shoulder orthosis Étude non communiquée | Myopathies · Sclérose latérale amyotrophique | Traitement symptomatique | Non applicable | Terminé | The goal of this clinical trial is to investigate the effect of a muscle-m… À vérifier | ClinicalTrials.gov 2026-09-02 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 585
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| HADANet: hybrid attentive domain adaptation for cross-subject motor i… INTENT Neural Interface System · PMID 42438682 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Motor imagery (MI) based brain-computer interfaces (BCIs) enable direct decoding of human motor intentions from neural… | Cognitive neurodynamics 2026-08-16 13:44:12 | Source |
| Integrating large language models into Peer-to-Peer energy management… INTENT Neural Interface System · PMID 41812359 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source While the integration of Large Language Models (LLMs) into Home Energy Management Systems (HEMS) promises intuitive int… | Neural networks : the official journal of the Internat… 2026-08-16 13:44:12 | Source |
| Technologies in clinical neurophysiology for brain-body interfacing:… INTENT Neural Interface System · PMID 42115034 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Interfacing the brain with the body represents a central challenge in contemporary clinical neurophysiology. Neurologic… | Clinical neurophysiology : official journal of the Int… 2026-08-16 13:44:12 | Source |
| Assessment of Xiao'er Xiexieting Keli-induced toxicity in juvenile ra… AB-1003 dose level 2 · PMID 42442643 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Sufficient safety data on juvenile development is not available for Xiao'er Xiexieting Keli (XXTK), a Chinese herbal fo… | Journal of ethnopharmacology 2026-08-16 13:26:14 | Source |
| In vivo antimalarial activity and acute toxicity of organic and aqueo… AB-1003 dose level 1 · PMID 42526550 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Globally, about 500,000 people die annually due to malaria. Emergence of drug-resistant parasite strains is the main dr… | Journal of ethnopharmacology 2026-08-16 13:26:11 | Source |
| Cosegregation of congenital dysferlinopathy phenotype and marinesco-s… CMDPROS — Congenital Muscle Disease Study of Patient and Family Reported Medical Information ·… | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The congenital dysferlinopathy phenotype is the rarest and earliest manifestation variant, described in two closely rel… | BMC pediatrics 2026-08-16 13:26:10 | Source |
| IFNα and bleomycin-induced DNA damage activate distinct stress respon… Stem Cell · PMID 42430551 | Myopathies | Immunomodulation · Thérapie cellulaire | Publication | PubMed | Voir la publication source Pancreatic β-cells undergo different stress responses during the development of type 1 diabetes (T1D), such as the type… | Islets 2026-08-16 13:26:09 | Source |
| Immune reconstitution and viral reactivation after allogeneic hematop… Stem Cell · PMID 42535760 | Myopathies | Thérapie cellulaire | Publication | PubMed | Voir la publication source To evaluate associations between post-transplant immune reconstitution, Epstein-Barr virus (EBV) and cytomegalovirus (C… | Hematology (Amsterdam, Netherlands) 2026-08-16 13:26:09 | Source |
| Nuclear mechanotransduction: tools for mechanical perturbation and ch… Stem Cell · PMID 42411057 | Myopathies | Remyélinisation indirecte / réparation · Thérapie cellulaire | Publication | PubMed | Voir la publication source Mechanical cues, ranging from matrix mechanical properties to dynamic mechanical loading, can be transmitted via struct… | Nucleus (Austin, Tex.) 2026-08-16 13:26:09 | Source |
| Comparison of pressure release, phonophoresis and dry needling in tre… Effect of Phonophoresis on Trigger Points · PMID 30584120 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Latent myofascial trigger point (LMTP) is a small hypersensitive area in skeletal muscles that becomes painful under co… | Journal of back and musculoskeletal rehabilitation 2026-08-16 13:26:08 | Source |
| Synergistic effect of dry needling and instrument-assisted soft tissu… Dry Needling for Myofascial Pain Syndrome · PMID 41431426 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate the augmented effects of trigger point dry needling (TPDN) and instrument-assisted soft tissue mobilization… | The Journal of manual & manipulative therapy 2026-08-16 13:26:06 | Source |
| Comparative efficacy of arthrocentesis, platelet-rich plasma (PRP), a… Splint Therapy · PMID 42302358 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Temporomandibular joint (TMJ) arthrocentesis has emerged as a minimally invasive intervention to improve jaw function a… | Journal of cranio-maxillo-facial surgery : official pu… 2026-08-16 13:26:05 | Source |
| Occlusal Splint Therapy in the Management of Temporomandibular Disord… Splint Therapy · PMID 42059781 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Occlusal splints are commonly used to manage temporomandibular disorders (TMDs), yet their efficacy remains controversi… | Journal of oral rehabilitation 2026-08-16 13:26:05 | Source |
| Promotion of condylar remodeling following disc repositioning surgery… Splint Therapy · PMID 42603532 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source This retrospective case series aimed to evaluate clinical and MRI-based changes after temporomandibular joint (TMJ) dis… | Journal of cranio-maxillo-facial surgery : official pu… 2026-08-16 13:26:05 | Source |
| Comprehensive phytochemical and pharmacological investigation of Cyno… (-)-Epicatechin · PMID 42242600 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Cynoglossum clandestinum Desf. (C. clandestinum Desf.) is a wild Moroccan medicinal species traditionally used for woun… | Journal of ethnopharmacology 2026-08-16 13:25:58 | Source |
| Danicamtiv increases cardiac mechanical efficiency. danicamtiv · PMID 40911791 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Danicamtiv is a recently developed cardiac-specific myosin activator that directly increases actomyosin interaction and… | The Journal of physiology 2026-08-16 13:25:58 | Source |
| flower extract enhances antioxidant defense and wound healing effects… (-)-Epicatechin · PMID 41995694 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Wound healing requires coordinated keratinocyte and fibroblast migration, extracellular matrix (ECM) deposition, and gr… | Pharmaceutical biology 2026-08-16 13:25:58 | Source |
| Unlocking hypoglycemic effect of black highland barley by targeting α… (-)-Epicatechin · PMID 42177877 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Highland barley is a unique crop of the Qinghai-Tibet Plateau, and its hypoglycemic properties have attracted extensive… | Talanta 2026-08-16 13:25:58 | Source |
| Anaesthetic efficacy of intraligamentary injection compared to incisi… Mepivacaine Hydrochloride · PMID 39825316 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source In dentistry, local anesthetic is frequently used to manage pain throughout several phases of dental treatments, includ… | BMC oral health 2026-08-16 13:25:54 | Source |
| Lidocaine spray vs mepivacaine local infiltration for suturing 1st/2n… Mepivacaine Hydrochloride · PMID 38914976 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Perineal lacerations are a very common complication of post-partum. Usually, the repair of 1st and 2nd-grade laceration… | BMC pregnancy and childbirth 2026-08-16 13:25:54 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |