Traitements3programmes
Essais1liés
Publications1liées
SourceDBlocale

Traitements

3
MoléculeIndication / populationPhaseObjectifPaysRésultat
XmAb541The primary purpose of this study is to determine whether the combination of the investigational drug XmAb541 in combination with the investigational drug XmAb808 is safe and well tolerated, and to determine an optimal and safe dose(s) for further study. The study will also evaluate the effect of XmAb541 in combination with XmAb808 on participants' tumor outcomes. Cancer Phase 1 À vérifier United States À vérifier
XmAb808The primary purpose of this study is to determine whether the combination of the investigational drug XmAb541 in combination with the investigational drug XmAb808 is safe and well tolerated, and to determine an optimal and safe dose(s) for further study. The study will also evaluate the effect of XmAb541 in combination with XmAb808 on participants' tumor outcomes. Cancer Phase 1 À vérifier United States À vérifier
XmAb541The primary purpose of this study is to determine whether the combination of the investigational drug XmAb541 in combination with the investigational drug XmAb808 is safe and well tolerated, and to determine an optimal and safe dose(s) for further study. The study will also evaluate the effect of XmAb541 in combination with XmAb808 on participants' tumor outcomes. Cancer Phase 1 À vérifier United States À vérifier

Essais cliniques

1
MoléculeIndication / populationPhaseNCTTitreStatut
XmAb541 Cancer Phase 1 NCT07593092 Phase 1, Safety and Tolerability Study of XmAb541 and XmAb808 in Advanced Solid Tumors RECRUITING

Publications

1
MoléculeIndication / populationTitreJournalDate
XmAb808 A B7-H3-Targeted CD28 Bispecific Antibody Enhances the Activity of Anti-PD-1 and CD3 T-cell Engager Immunotherapies. Molecular cancer therapeutics