University Medical Centre Ljubljana — Biomedical Watch V2

Traitements4programmes

Essais2liés

Publications3liées

SourceDBlocale

Traitements

4

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
ACUPMIGRAINE — The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in MigraineMigraine is more than just a headache-it can involve changes in the brain and inflammation. Recent research suggests that acupuncture may help by calming pain signals and reducing inflammation in the body. Scientists are studying whether acupuncture can also lower certain markers in the blood that show brain stress or inflammation. While more research is needed, acupuncture is considered safe and may reduce the number and severity of migraine attacks for many people. Acupuncture has been used for over 40 years in our practice to manage acute and chronic pain, including migraines. When performed by trained physicians, it is safe and typically reduces headache frequency and intensity, as well as nausea and vomiting, lowering the need for pain medication. Investigators are exploring three different ways to help manage migraine headaches using gentle stimulation techniques. These include laser acupuncture, electroacupuncture, and traditional acupuncture. Investigators want to see which method works best for reducing migraine symptoms. Investigators will look at how participants feel after treatment and also check blood samples for signs of inflammation and certain substances linked to migraines, such as calcitonin gene-related peptide (CGRP) and markers of brain stress. Investigators have a goal to find safe and effective options that can improve migraine care and help people feel better.	Migraine	Non applicable	Traitement symptomatique	Slovenia	À vérifier
Selective vagus nerve stimulationThe investigators would like to explore possibilities of selective vagus nerve stimulation in human subjects to control heart rate and arterial blood pressure.	Hypertension	NA	À vérifier	Slovenia	À vérifier
Selective vagus nerve stimulationThe investigators would like to explore possibilities of selective vagus nerve stimulation in human subjects to control heart rate and arterial blood pressure.	Hypertension	NA	À vérifier	Slovenia	À vérifier
ACUPMIGRAINE — The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in MigraineMigraine is more than just a headache-it can involve changes in the brain and inflammation. Recent research suggests that acupuncture may help by calming pain signals and reducing inflammation in the body. Scientists are studying whether acupuncture can also lower certain markers in the blood that show brain stress or inflammation. While more research is needed, acupuncture is considered safe and may reduce the number and severity of migraine attacks for many people. Acupuncture has been used for over 40 years in our practice to manage acute and chronic pain, including migraines. When performed by trained physicians, it is safe and typically reduces headache frequency and intensity, as well as nausea and vomiting, lowering the need for pain medication. Investigators are exploring three different ways to help manage migraine headaches using gentle stimulation techniques. These include laser acupuncture, electroacupuncture, and traditional acupuncture. Investigators want to see which method works best for reducing migraine symptoms. Investigators will look at how participants feel after treatment and also check blood samples for signs of inflammation and certain substances linked to migraines, such as calcitonin gene-related peptide (CGRP) and markers of brain stress. Investigators have a goal to find safe and effective options that can improve migraine care and help people feel better.	Migraine	Non applicable	Traitement symptomatique	Slovenia	À vérifier

Essais cliniques

2

Molécule	Indication / population	Phase	NCT	Titre	Statut
ACUPMIGRAINE — The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in Migraine	Migraine	Non applicable	NCT07292506	ACUPMIGRAINE — The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in Migraine	ACTIVE_NOT_RECRUITING
Selective vagus nerve stimulation	Hypertension	NA	NCT00983632	VNS — Selective Vagus Nerve Stimulation in Human	COMPLETED

Publications

3

Molécule	Indication / population	Titre	Journal	Date
Selective vagus nerve stimulation		kHz-frequency electrical stimulation selectively activates small, unmyelinated vagus afferents.	Brain stimulation
Selective vagus nerve stimulation		A combined cuff electrode array for organ-specific selective stimulation of vagus nerve enabled by Electrical Impedance Tomography.	Frontiers in medical technology
Selective vagus nerve stimulation		Towards spatially selective efferent neuromodulation: anatomical and functional organization of cardiac fibres in the porcine cervical vagus nerve.	The Journal of physiology