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University Medical Center Groningen
Traitements, essais et publications liés.
Traitements2programmes
Essais1liés
Publications2liées
SourceDBlocale
Traitements
2| Molécule | Indication / population | Phase | Objectif | Pays | Résultat |
|---|---|---|---|---|---|
| [18F]MC225P-glycoprotein, an efflux transporter at the blood-brain barrier plays an important role in de development of neurodegenerative disease. A novel PET tracer (\[18F\]MC225) was developed to measure the function of P-glycoprotein and was tested with succes in healthy volunteers. This study aims to evaluate \[18F\]MC225 in neurodegenerative disease. | Alzheimer, Parkinson | Phase 1 | À vérifier | Netherlands | À vérifier |
| [18F]MC225P-glycoprotein, an efflux transporter at the blood-brain barrier plays an important role in de development of neurodegenerative disease. A novel PET tracer (\[18F\]MC225) was developed to measure the function of P-glycoprotein and was tested with succes in healthy volunteers. This study aims to evaluate \[18F\]MC225 in neurodegenerative disease. | Alzheimer | Phase 1 | À vérifier | Netherlands | À vérifier |
Essais cliniques
1| Molécule | Indication / population | Phase | NCT | Titre | Statut |
|---|---|---|---|---|---|
| [18F]MC225 | Alzheimer | Phase 1 | NCT05853471 | [18F]MC225-PET in Neurodegenerative Disease | UNKNOWN |
Publications
2| Molécule | Indication / population | Titre | Journal | Date |
|---|---|---|---|---|
| [18F]MC225 | P-glycoprotein Function in the Rodent Brain Displays a Daily Rhythm, a Quantitative In Vivo PET Study. | The AAPS journal | ||
| [18F]MC225 | assessment of cardiac P-glycoprotein function with [F]MC225 by using µ-engineered heart tissues. | European heart journal open |