Uludag University — Biomedical Watch V2

Traitements5programmes

Essais2liés

Publications3liées

SourceDBlocale

Traitements

5

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Home-Based Exercise Programs for Fall Prevention in Parkinson DiseaseFalls are common in patients with Parkinson disease and may lead to reduced mobility, fear of falling, loss of independence, and injury. Exercise-based rehabilitation programs may help improve balance, gait, and physical performance in this population. This randomized controlled trial aims to compare the effectiveness of two home-based exercise programs in patients with Parkinson disease: the Otago Exercise Program and a structured home exercise program. Participants will be randomly assigned to one of two groups. Both groups will receive exercise education and will perform their assigned home exercise program for 6 weeks. Participants will be evaluated at baseline, at week 3, and at the end of week 6. The study will assess fall-related outcomes, freezing of gait, functional mobility, gait parameters, postural control, and physical performance. The results may help determine which home-based exercise approach is more effective for reducing fall risk and improving functional outcomes in patients with Parkinson disease.	Parkinson	Non applicable	À vérifier	Turkey (Türkiye)	À vérifier
Sham whole body vibration therapyThe purpose of this clinical study is to evaluate the effect of Whole Body Vibration (WBV) therapy, applied two weeks after botulinum toxin type A (BoNT-A) injection, on spasticity and balance parameters in individuals with stroke who have ankle spasticity. The main questions it aims to answer are: Adjuvant WBV therapy administered after BoNT-A injection; * Does it effectively improve spasticity? * Is it an effective intervention for balance and walking functions? Researchers will compare the application of WBV to a placebo application (a vibration-free application) to evaluate the effect of adjuvant WBV therapy administered after BoNT-A injection on ankle spasticity, balance, and walking function in individuals with stroke.	Myopathies	Non applicable	Traitement symptomatique	Turkey (Türkiye)	À vérifier
Whole body vibration therapyThe purpose of this clinical study is to evaluate the effect of Whole Body Vibration (WBV) therapy, applied two weeks after botulinum toxin type A (BoNT-A) injection, on spasticity and balance parameters in individuals with stroke who have ankle spasticity. The main questions it aims to answer are: Adjuvant WBV therapy administered after BoNT-A injection; * Does it effectively improve spasticity? * Is it an effective intervention for balance and walking functions? Researchers will compare the application of WBV to a placebo application (a vibration-free application) to evaluate the effect of adjuvant WBV therapy administered after BoNT-A injection on ankle spasticity, balance, and walking function in individuals with stroke.	Myopathies	Non applicable	Traitement symptomatique	Turkey (Türkiye)	À vérifier
Home-Based Exercise Programs for Fall Prevention in Parkinson DiseaseFalls are common in patients with Parkinson disease and may lead to reduced mobility, fear of falling, loss of independence, and injury. Exercise-based rehabilitation programs may help improve balance, gait, and physical performance in this population. This randomized controlled trial aims to compare the effectiveness of two home-based exercise programs in patients with Parkinson disease: the Otago Exercise Program and a structured home exercise program. Participants will be randomly assigned to one of two groups. Both groups will receive exercise education and will perform their assigned home exercise program for 6 weeks. Participants will be evaluated at baseline, at week 3, and at the end of week 6. The study will assess fall-related outcomes, freezing of gait, functional mobility, gait parameters, postural control, and physical performance. The results may help determine which home-based exercise approach is more effective for reducing fall risk and improving functional outcomes in patients with Parkinson disease.	Parkinson	Non applicable	À vérifier	Turkey (Türkiye)	À vérifier
Whole body vibration therapyThe purpose of this clinical study is to evaluate the effect of Whole Body Vibration (WBV) therapy, applied two weeks after botulinum toxin type A (BoNT-A) injection, on spasticity and balance parameters in individuals with stroke who have ankle spasticity. The main questions it aims to answer are: Adjuvant WBV therapy administered after BoNT-A injection; * Does it effectively improve spasticity? * Is it an effective intervention for balance and walking functions? Researchers will compare the application of WBV to a placebo application (a vibration-free application) to evaluate the effect of adjuvant WBV therapy administered after BoNT-A injection on ankle spasticity, balance, and walking function in individuals with stroke.	Myopathies	Non applicable	Traitement symptomatique	Turkey (Türkiye)	À vérifier

Essais cliniques

2

Molécule	Indication / population	Phase	NCT	Titre	Statut
Whole body vibration therapy	Myopathies	Non applicable	NCT07286435	The Effect of Whole-Body Vibration Therapy Following Botulinum Toxin A Injection on Spasticity and Balance in Stroke Patients	RECRUITING
Home-Based Exercise Programs for Fall Prevention in Parkinson Disease	Parkinson	Non applicable	NCT07590700	Home-Based Exercise Programs for Fall Prevention in Parkinson Disease	COMPLETED

Publications

3

Molécule	Indication / population	Titre	Journal	Date
Home-Based Exercise Programs for Fall Prevention in Parkinson Disease		'PDSAFE' - a multi-dimensional model of falls-rehabilitation for people with Parkinson's. A mixed methods analysis of therapists' delivery and experience.	Physiotherapy
Home-Based Exercise Programs for Fall Prevention in Parkinson Disease		Acceptability of a programme for safer mobility (INTEGRATE): Perspectives of people with Parkinson's disease and their care-partners.	Clinical rehabilitation
Home-Based Exercise Programs for Fall Prevention in Parkinson Disease		Fractures in Parkinson's Disease: Pathophysiology, Prevention, and Orthopedic Outcomes.	Cureus