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The University of Texas Health Science Center, Houston
Traitements, essais et publications liés.
Traitements10programmes
Essais4liés
Publications13liées
SourceDBlocale
Traitements
10| Molécule | Indication / population | Phase | Objectif | Pays | Résultat |
|---|---|---|---|---|---|
| Acupuncture interventionThe purpose of this study is to determine effects of Acupuncture on a Patient's mood and cognition,evaluate changes in clinically-reported seizure frequency and severity and analyze effects of Acupuncture on electrographic epileptiform activity stored by the RNS System | Épilepsie | NA | À vérifier | United States | À vérifier |
| Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA)The objectives of this study are to determine the feasibility, tolerability, and treatment effect of endoscopic ultrasound (EUS) radiofrequency ablation (RFA) plus standard-of-care neoadjuvant chemotherapy (NAC) in the treatment of pancreatic ductal adenocarcinoma (PDAC). Endoscopic ultrasound (EUS) radiofrequency ablation (RFA) and neoadjuvant chemotherapy (NAC) will be performed before tumor resection surgery, with the goal of shrinking a tumor or stopping the spread of cancer so that surgery might be less invasive and more effective. | Cancer | Phase 2 | À vérifier | United States | À vérifier |
| Fenfluramine treatment (Fintepla)This study investigates cerebrovascular reactivity (CVR) and functional brain connectivity in Dravet Syndrome (DS) patients with convulsive seizures. Using functional MRI (fMRI), we will define differences in brain responses to CO₂ changes before administration of the drug Fintepla (Baseline), with a library of healthy controls and with those obtained after administration of Fintepla (Day \~60). Changes in CVR and their relation to ventilatory responses will also be assessed during fMRI. | Épilepsie | Phase 4 | À vérifier | United States | À vérifier |
| Hypercapnia Challenge using the device (RespirAct)This study investigates cerebrovascular reactivity (CVR) and functional brain connectivity in Dravet Syndrome (DS) patients with convulsive seizures. Using functional MRI (fMRI), we will define differences in brain responses to CO₂ changes before administration of the drug Fintepla (Baseline), with a library of healthy controls and with those obtained after administration of Fintepla (Day \~60). Changes in CVR and their relation to ventilatory responses will also be assessed during fMRI. | Épilepsie | Phase 4 | À vérifier | United States | À vérifier |
| Neoadjuvant Chemotherapy (NAC)The objectives of this study are to determine the feasibility, tolerability, and treatment effect of endoscopic ultrasound (EUS) radiofrequency ablation (RFA) plus standard-of-care neoadjuvant chemotherapy (NAC) in the treatment of pancreatic ductal adenocarcinoma (PDAC). Endoscopic ultrasound (EUS) radiofrequency ablation (RFA) and neoadjuvant chemotherapy (NAC) will be performed before tumor resection surgery, with the goal of shrinking a tumor or stopping the spread of cancer so that surgery might be less invasive and more effective. | Cancer | Phase 2 | À vérifier | United States | À vérifier |
| VAMOS-MS — Delivery of a Culturally Tailored Exercise Training Intervention for Hispanics With Multiple SclerosisThe purpose of this study is to establish differences in the primary outcome of walking dysfunction using the 12-Item Multiple Sclerosis Walking Scale (MSWS-12) and to establish differences in the secondary outcome of HRQoL using the 29-Item Multiple Sclerosis Walking Scale (MSWS-29) between the exercise training intervention condition and the waitlist control condition following the 16-week intervention period. | SEP | Non applicable | À vérifier | United States | À vérifier |
| Acupuncture interventionThe purpose of this study is to determine effects of Acupuncture on a Patient's mood and cognition,evaluate changes in clinically-reported seizure frequency and severity and analyze effects of Acupuncture on electrographic epileptiform activity stored by the RNS System | Épilepsie | NA | À vérifier | United States | À vérifier |
| Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA)The objectives of this study are to determine the feasibility, tolerability, and treatment effect of endoscopic ultrasound (EUS) radiofrequency ablation (RFA) plus standard-of-care neoadjuvant chemotherapy (NAC) in the treatment of pancreatic ductal adenocarcinoma (PDAC). Endoscopic ultrasound (EUS) radiofrequency ablation (RFA) and neoadjuvant chemotherapy (NAC) will be performed before tumor resection surgery, with the goal of shrinking a tumor or stopping the spread of cancer so that surgery might be less invasive and more effective. | Cancer | Phase 2 | À vérifier | United States | À vérifier |
| VAMOS-MS — Delivery of a Culturally Tailored Exercise Training Intervention for Hispanics With Multiple SclerosisThe purpose of this study is to establish differences in the primary outcome of walking dysfunction using the 12-Item Multiple Sclerosis Walking Scale (MSWS-12) and to establish differences in the secondary outcome of HRQoL using the 29-Item Multiple Sclerosis Walking Scale (MSWS-29) between the exercise training intervention condition and the waitlist control condition following the 16-week intervention period. | SEP | Non applicable | À vérifier | United States | À vérifier |
| Fenfluramine treatment (Fintepla)This study investigates cerebrovascular reactivity (CVR) and functional brain connectivity in Dravet Syndrome (DS) patients with convulsive seizures. Using functional MRI (fMRI), we will define differences in brain responses to CO₂ changes before administration of the drug Fintepla (Baseline), with a library of healthy controls and with those obtained after administration of Fintepla (Day \~60). Changes in CVR and their relation to ventilatory responses will also be assessed during fMRI. | Épilepsie | Phase 4 | À vérifier | United States | À vérifier |
Essais cliniques
4| Molécule | Indication / population | Phase | NCT | Titre | Statut |
|---|---|---|---|---|---|
| Fenfluramine treatment (Fintepla) | Épilepsie | Phase 4 | NCT07112365 | FAST-DS — The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome Project | RECRUITING |
| VAMOS-MS — Delivery of a Culturally Tailored Exercise Training Intervention for Hispanics With Multiple Sclerosis | SEP | Non applicable | NCT07606742 | VAMOS-MS — Delivery of a Culturally Tailored Exercise Training Intervention for Hispanics With Multiple Sclerosis | RECRUITING |
| Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA) | Cancer | Phase 2 | NCT04990609 | EUS-RFA PANCARDINAL-1 Trial | RECRUITING |
| Acupuncture intervention | Épilepsie | NA | NCT04677751 | Clinical and Electrographic Changes in Responsive Neurostimulation System (RNS) Patients with Acupuncture Treatment | RECRUITING |
Publications
13| Molécule | Indication / population | Titre | Journal | Date |
|---|---|---|---|---|
| Acupuncture intervention | Efficacy of Acupuncture for Insomnia After Chemotherapy in Breast Cancer: A Randomized Sham-Controlled Trial. | Nature and science of sleep | ||
| Acupuncture intervention | The effectiveness of wrist-ankle acupuncture on post-stroke shoulder-hand syndrome: A systematic review and meta-analysis. | International journal of nursing studies advances | ||
| Neoadjuvant Chemotherapy (NAC) | Impact of neoadjuvant chemotherapy on postoperative outcomes in intrahepatic cholangiocarcinoma: A propensity-matched analysis. | American journal of surgery | ||
| Neoadjuvant Chemotherapy (NAC) | Axillary treatment options in clinically nodes-positive breast cancer whose nodes become pathologically nodes-negative after neoadjuvant chemotherapy: a pairwise and network meta-analysis. | Annals of medicine | ||
| Neoadjuvant Chemotherapy (NAC) | Evaluating the Feasibility of Breast-Conserving Surgery in Breast Cancer Patients with Suspicious Calcifications After Neoadjuvant Chemotherapy: A Retrospective Cohort Study. | Journal of investigative surgery : the official journal of the Academy of Surgical Research | ||
| Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA) | Endoscopic ultrasound-guided radiofrequency ablation of pancreatic insulinoma. | Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery | ||
| Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA) | Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA): Are We Getting Evidence-Based Results? A Systematic Review According to the Levels of Evidence. | Medicina (Kaunas, Lithuania) | ||
| Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA) | Endoscopic Ultrasound-Guided Radiofrequency Ablation for Pancreatic Metastases: Safety and Clinical Outcomes in a Single-Center Case Series. | Journal of clinical medicine | ||
| Acupuncture intervention | A systematic review and meta-analysis of acupuncture for intestinal protection and underlying mechanisms in animal models of ulcerative colitis. | Medicine | ||
| Acupuncture intervention | Screw-Thread Needle Mediated In Situ Delivery of Tangeretin@β-Cyclodextrin Sulfated Sodium Salt Complexes for the Therapy of Achilles Tendinitis. | ACS applied bio materials | ||
| Acupuncture intervention | Neuroimaging biomarkers for predicting acupuncture treatment response in chronic pain: a systematic review and meta-analysis protocol. | BMJ open | ||
| Acupuncture intervention | [Effect of eye acupuncture on mitophagy in neurons of ischemic cortical brain tissue in rats with cerebral ischemia reperfusion injury based on AMPK/ULK1/FUNDC1 signaling axis]. | Zhongguo zhen jiu = Chinese acupuncture & moxibustion | ||
| Acupuncture intervention | [Approach to brain effect research: exploring the connection among "acupoint sensitization, mental-physical response and " from the perspective of "feeling comfortable when acupoint is pressed"]. | Zhongguo zhen jiu = Chinese acupuncture & moxibustion |