The Hong Kong Polytechnic University — Biomedical Watch V2

Traitements8programmes

Essais3liés

Publications19liées

SourceDBlocale

Traitements

8

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
AcupunctureThe goal of this clinical trial is to determine the effectiveness of Tai Chi training and acupuncture on the migraine attacks and structural brain changes in women with episodic migraine. Researchers will compare Tai Chi training to acupuncture treatment in a randomized controlled trial with 132 female participants. Participants will: * Be randomly assigned to either the Tai Chi group or the acupuncture group. * Undergo a 24-week intervention, with structured sessions for Tai Chi or scheduled acupuncture treatments. * Complete assessments through migraine diaries, questionnaires, physical measurements, MRI and TCD scans at various time points. The study ensures participant safety through close monitoring, with medical support available in case of discomfort. Data confidentiality will be maintained, with encrypted storage and restricted access for research purposes.	Migraine	Non applicable	À vérifier	Hong Kong	À vérifier
ControlUpper limb impairment is present in more than 85% of people with stroke, which greatly affect the quality of life, social participation, and performance of daily activities of people with stroke. Previous study also revealed that 53.4% of people after stroke experienced cognitive impairment. Different cognitive domains might be affected following stroke, such as attention, memory, language, and orientation, and the problems with memory are often prominent. Yet, there is no effective treatment for the post-stroke cognitive impairment. Transcutaneous spinal cord stimulation (tSCS) and transcutaneous vagus nerve stimulation (tVNS) are simple and non-invasive treatment to improve upper limb motor function and cognitive function. However, no existing studies have explored on the effects of tSCS and tVNS on cognitive function in people with stroke. Therefore, the purpose of this study is to evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS) on improving upper limb function and cognitive function in people with chronic stroke.	SEP	Non applicable	À vérifier	Hong Kong	À vérifier
Standard prophylactic medicationThe proposed study aims to examine the clinical efficacy of 24-week Tai Chi training in the prophylaxis of episodic migraine comparing with standard prophylactic medication in Hong Kong Chinese women, and to explore the mechanism of Tai Chi's intervention effect by examining the associations of changes in migraine features with neurovascular and neuroinflammation variations.	Migraine	Non applicable	Immunomodulation	Hong Kong	À vérifier
tSCSUpper limb impairment is present in more than 85% of people with stroke, which greatly affect the quality of life, social participation, and performance of daily activities of people with stroke. Previous study also revealed that 53.4% of people after stroke experienced cognitive impairment. Different cognitive domains might be affected following stroke, such as attention, memory, language, and orientation, and the problems with memory are often prominent. Yet, there is no effective treatment for the post-stroke cognitive impairment. Transcutaneous spinal cord stimulation (tSCS) and transcutaneous vagus nerve stimulation (tVNS) are simple and non-invasive treatment to improve upper limb motor function and cognitive function. However, no existing studies have explored on the effects of tSCS and tVNS on cognitive function in people with stroke. Therefore, the purpose of this study is to evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS) on improving upper limb function and cognitive function in people with chronic stroke.	SEP	Non applicable	À vérifier	Hong Kong	À vérifier
tVNSUpper limb impairment is present in more than 85% of people with stroke, which greatly affect the quality of life, social participation, and performance of daily activities of people with stroke. Previous study also revealed that 53.4% of people after stroke experienced cognitive impairment. Different cognitive domains might be affected following stroke, such as attention, memory, language, and orientation, and the problems with memory are often prominent. Yet, there is no effective treatment for the post-stroke cognitive impairment. Transcutaneous spinal cord stimulation (tSCS) and transcutaneous vagus nerve stimulation (tVNS) are simple and non-invasive treatment to improve upper limb motor function and cognitive function. However, no existing studies have explored on the effects of tSCS and tVNS on cognitive function in people with stroke. Therefore, the purpose of this study is to evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS) on improving upper limb function and cognitive function in people with chronic stroke.	SEP	Non applicable	À vérifier	Hong Kong	À vérifier
AcupunctureThe goal of this clinical trial is to determine the effectiveness of Tai Chi training and acupuncture on the migraine attacks and structural brain changes in women with episodic migraine. Researchers will compare Tai Chi training to acupuncture treatment in a randomized controlled trial with 132 female participants. Participants will: * Be randomly assigned to either the Tai Chi group or the acupuncture group. * Undergo a 24-week intervention, with structured sessions for Tai Chi or scheduled acupuncture treatments. * Complete assessments through migraine diaries, questionnaires, physical measurements, MRI and TCD scans at various time points. The study ensures participant safety through close monitoring, with medical support available in case of discomfort. Data confidentiality will be maintained, with encrypted storage and restricted access for research purposes.	Migraine	Non applicable	À vérifier	Hong Kong	À vérifier
tSCSUpper limb impairment is present in more than 85% of people with stroke, which greatly affect the quality of life, social participation, and performance of daily activities of people with stroke. Previous study also revealed that 53.4% of people after stroke experienced cognitive impairment. Different cognitive domains might be affected following stroke, such as attention, memory, language, and orientation, and the problems with memory are often prominent. Yet, there is no effective treatment for the post-stroke cognitive impairment. Transcutaneous spinal cord stimulation (tSCS) and transcutaneous vagus nerve stimulation (tVNS) are simple and non-invasive treatment to improve upper limb motor function and cognitive function. However, no existing studies have explored on the effects of tSCS and tVNS on cognitive function in people with stroke. Therefore, the purpose of this study is to evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS) on improving upper limb function and cognitive function in people with chronic stroke.	SEP	Non applicable	À vérifier	Hong Kong	À vérifier
Standard prophylactic medicationThe proposed study aims to examine the clinical efficacy of 24-week Tai Chi training in the prophylaxis of episodic migraine comparing with standard prophylactic medication in Hong Kong Chinese women, and to explore the mechanism of Tai Chi's intervention effect by examining the associations of changes in migraine features with neurovascular and neuroinflammation variations.	Migraine	Non applicable	Immunomodulation	Hong Kong	À vérifier

Essais cliniques

3

Molécule	Indication / population	Phase	NCT	Titre	Statut
Standard prophylactic medication	Migraine	Non applicable	NCT05690737	Tai Chi for the Prophylaxis of Episodic Migraine: the Efficacy Examination and Mechanism Exploration	COMPLETED
tSCS	SEP	Non applicable	NCT05615610	Effects of Transcutaneous Electrical Nerve Stimulation on Cognitive Function and Upper Limb Motor Function in People With Chronic Stroke	RECRUITING
Acupuncture	Migraine	Non applicable	NCT06967909	Tai Chi and Acupuncture on Migraine Attack Prevention and Brain White Matter Changes	RECRUITING

Publications

19

Molécule	Indication / population	Titre	Journal	Date
Acupuncture		Current treatment for erectile dysfunction: an umbrella review of systematic reviews and meta-analyses.	The aging male : the official journal of the International Society for the Study of the Aging Male
Acupuncture		Rotation-traction manipulation versus cervical traction for axial neck pain caused by cervical degenerative disc disease: a multicenter randomized controlled trial.	The Libyan journal of medicine
Control		Gastric Metastasis of Uterine Leiomyosarcoma Detected During Surveillance Endoscopy and Resected by Endoscopic Submucosal Dissection After Multiple Metachronous Metastases: A Case Report.	DEN open
Control		Update on Sedation for Upper Gastrointestinal Endoscopy in Japan: Current Evidence on Remimazolam.	DEN open
Control		Minimal supply chain and forecasting testing volumes for clinical bacteriology laboratories in resource-limited settings for individual patient care: a costing study.	The Lancet. Microbe
tVNS		Monocyte Oxidative Stress Underlies Persistent Immune Activation in Long COVID Postural Orthostatic Tachycardia Syndrome.	medRxiv : the preprint server for health sciences
tVNS		Transcutaneous vagus nerve stimulation enhances reward-effort efficiency in severe major depressive disorder.	Journal of affective disorders
tSCS		The imprinted Peg3 gene is a potent regulator of the DNA methylome in trophoblast cells.	Stem cell reports
tSCS		Combined activity-based therapy and transcutaneous spinal cord stimulation as an intensification and supplemental approach for upper limb sensorimotor recovery: a randomised controlled trial protocol for in-patients with subacute spinal cord injury.	BMJ open
tSCS		Bio-Inspired lipid nanovesicles (iNVs) incorporating membrane proteins from healthy tendon stem cells for targeted protein restoration in tendinopathic model.	Artificial cells, nanomedicine, and biotechnology
Acupuncture		Effectiveness and Safety of Herbal Decoctions for Functional Dyspepsia in Korean Medicine Clinics: A Multicenter Prospective Cohort Study Protocol.	Healthcare (Basel, Switzerland)
Acupuncture		Intravaginal Formulation Strategies for Vaginal Disorders: Optimizing Phytochemical and Biological Preparations-A Review.	Molecules (Basel, Switzerland)
Control		Impact of community-led cancer advocacy program on cancer health outreach and research navigation among immigrants of African descent.	Frontiers in health services
Control		When prediction fails: a computational complexity view of stress.	Frontiers in veterinary science
tVNS		Transcutaneous vagus nerve stimulation in sleep disorders: current evidence and future directions.	Frontiers in pain research (Lausanne, Switzerland)
tVNS		tVNS and obesity-related inflammation: a prospective sham-controlled randomized crossover study protocol.	BMC psychology
tSCS		Prehospital Validation of the Scale to Identify Large Vessel Occlusion in Suspected Stroke Patients.	Cerebrovascular diseases (Basel, Switzerland)
tSCS		A Systematic Review of Stimulation Parameters Used in Transcutaneous Spinal Cord Stimulation for Upper Body Rehabilitation in People with Cervical Spinal Cord Injury.	Neuromodulation : journal of the International Neuromodulation Society
Acupuncture		Effectiveness of acupuncture and related therapies for post-stroke insomnia: A systematic review and Bayesian network analysis.	Medicine