The First Affiliated Hospital of Anhui Medical University — Biomedical Watch V2

Traitements2programmes

Essais1liés

Publications2liées

SourceDBlocale

Traitements

2

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
The Efficacy and Safety of Temporal Interference Stimulation on Motor Symptoms of Parkinson's DiseaseThis study aimed to evaluate the clinical efficacy and safety of temporal interference stimulation (TIS) targeting different targets in patients with Parkinson's disease (PD), and to investigate the associated neurophysiological mechanisms. A three-arm, randomised, double-blind, parallel-group design was employed, consisting of a right globus pallidus internus (GPi) stimulation group, a right subthalamic nucleus (STN) stimulation group, and a sham stimulation group. PD patients in the OFF-medication state (≥12 hours after the last dopaminergic dose) were randomly assigned to receive either active TIS targeting the GPi or STN, or sham stimulation, with each session lasting 30 minutes. Clinical symptom assessments were conducted before and immediately after the intervention, and safety was monitored throughout by the research team.	Parkinson	Non applicable	Traitement symptomatique	China	À vérifier
The Efficacy and Safety of Temporal Interference Stimulation on Motor Symptoms of Parkinson's DiseaseThis study aimed to evaluate the clinical efficacy and safety of temporal interference stimulation (TIS) targeting different targets in patients with Parkinson's disease (PD), and to investigate the associated neurophysiological mechanisms. A three-arm, randomised, double-blind, parallel-group design was employed, consisting of a right globus pallidus internus (GPi) stimulation group, a right subthalamic nucleus (STN) stimulation group, and a sham stimulation group. PD patients in the OFF-medication state (≥12 hours after the last dopaminergic dose) were randomly assigned to receive either active TIS targeting the GPi or STN, or sham stimulation, with each session lasting 30 minutes. Clinical symptom assessments were conducted before and immediately after the intervention, and safety was monitored throughout by the research team.	Parkinson	Non applicable	Traitement symptomatique	China	À vérifier

Essais cliniques

1

Molécule	Indication / population	Phase	NCT	Titre	Statut
The Efficacy and Safety of Temporal Interference Stimulation on Motor Symptoms of Parkinson's Disease	Parkinson	Non applicable	NCT07572903	The Efficacy and Safety of Temporal Interference Stimulation on Motor Symptoms of Parkinson's Disease	COMPLETED

Publications

2

Molécule	Indication / population	Titre	Journal	Date
The Efficacy and Safety of Temporal Interference Stimulation on Motor Symptoms of Parkinson's Disease		Transcranial Temporal Interference Stimulation of the Right Globus Pallidus in Parkinson's Disease.	Movement disorders : official journal of the Movement Disorder Society
The Efficacy and Safety of Temporal Interference Stimulation on Motor Symptoms of Parkinson's Disease		Transcranial temporal interference stimulation targeting the subthalamic region for motor symptoms in Parkinson's disease: a pilot, randomised, double-blind, sham-controlled crossover study.	EBioMedicine