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The Cooper Health System
Traitements, essais et publications liés.
Traitements3programmes
Essais1liés
Publications7liées
SourceDBlocale
Traitements
3| Molécule | Indication / population | Phase | Objectif | Pays | Résultat |
|---|---|---|---|---|---|
| Lidocaine HydrochlorideThis randomized clinical trial will aim to compare the effectiveness of dry needling, lidocaine injection, and mepivacaine injection in the treatment of myofascial pain in the masticatory muscles. A total of 75 participants with bilateral active trigger points in the masseter and/or temporalis muscles will be enrolled and randomly assigned to three intervention groups. Each participant will receive weekly treatments for three weeks. Pain levels, depressive symptoms, and temporomandibular disorder severity will be assessed using the Visual Analog Scale, the Beck Depression Inventory, and the Fonseca Anamnestic Index. Outcome measures will be recorded at baseline and one week after the final treatment session. The primary objective of this study is to determine which intervention provides the greatest improvement in myofascial pain symptoms. | Migraine, Myopathies | Phase 1 | Traitement symptomatique | United States | À vérifier |
| Methylprednisolone sodium succinateThe goal of this clinical trial is to test whether injecting lidocaine and steroids into two blood vessels of the brain can help treat chronic headaches (migraines). The main questions this study aims to answer: is this treatment safe for chronic migraine patients? Participants will: * Be treated once with lidocaine and steroid infused into the middle meningeal arteries (two blood vessels in the brain). * Attend appointments scheduled 1 week, 6 weeks, and 12 weeks after the treatment for a checkup. * Keep a log of their symptoms. | Migraine | Phase 1 | Traitement symptomatique | United States | À vérifier |
| Lidocaine HydrochlorideThis randomized clinical trial will aim to compare the effectiveness of dry needling, lidocaine injection, and mepivacaine injection in the treatment of myofascial pain in the masticatory muscles. A total of 75 participants with bilateral active trigger points in the masseter and/or temporalis muscles will be enrolled and randomly assigned to three intervention groups. Each participant will receive weekly treatments for three weeks. Pain levels, depressive symptoms, and temporomandibular disorder severity will be assessed using the Visual Analog Scale, the Beck Depression Inventory, and the Fonseca Anamnestic Index. Outcome measures will be recorded at baseline and one week after the final treatment session. The primary objective of this study is to determine which intervention provides the greatest improvement in myofascial pain symptoms. | Migraine | Phase 1 | Traitement symptomatique | United States | À vérifier |
Essais cliniques
1| Molécule | Indication / population | Phase | NCT | Titre | Statut |
|---|---|---|---|---|---|
| Lidocaine Hydrochloride | Migraine | Phase 1 | NCT06462781 | LIGHT 1 — Localized Injection of Lidocaine and Glucocorticoid for Headache Treatment Phase 1 | COMPLETED |
Publications
7| Molécule | Indication / population | Titre | Journal | Date |
|---|---|---|---|---|
| Methylprednisolone sodium succinate | Clinical characteristics and diagnostic indicators of childhood-onset systemic lupus erythematosus complicated with macrophage activation syndrome. | Clinical rheumatology | ||
| Lidocaine Hydrochloride | Topical delivery of Lidocaine using spicules for local anesthesia. | Drug delivery and translational research | ||
| Lidocaine Hydrochloride | Comparison between Perineural and Intravenous Dexamethasone on Duration of Analgesia in Supraclavicular Brachial Plexus Block - An Observational Study. | Annals of African medicine | ||
| Methylprednisolone sodium succinate | The impact of timing, dosage, and duration of high-dose methylprednisolone on neurological recovery and complications in acute spinal cord injury: A systematic review and meta-analysis of randomized controlled trials. | The journal of spinal cord medicine | ||
| Methylprednisolone sodium succinate | Effects of low-dose methylprednisolone sodium succinate on lung function and blood gas function in elderly patients with chronic obstructive pulmonary disease complicated with respiratory failure. | Pakistan journal of pharmaceutical sciences | ||
| Lidocaine Hydrochloride | Impact of Menthol Concentration on Ketoprofen Permeation and Photostability in Compounded Topical Preparations in a Pentravan Base. | ACS omega | ||
| Lidocaine Hydrochloride | Compound Chamomile and Lidocaine Hydrochloride Gel in Oral Diseases: A Review of Current Evidence and Potential Applications. | Drug design, development and therapy |