Singapore General Hospital — Biomedical Watch V2

Traitements5programmes

Essais3liés

Publications4liées

SourceDBlocale

Traitements

5

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
EUSRA RFA needleThis study aims to evaluate the safety and efficacy of new ablation catheter developed by MEDICAL TAEWOONG for the treatment of pancreatic neoplasm (pancreatic adenocarcinoma or neuroendocrine tumour). The ablation is performed using EUSRA needle and radio frequency waves under ultrasound imaging. The subject who will be recruited into this study are patients who are deemed as non-surgical candidates.	Cancer	Non applicable	À vérifier	Singapore	À vérifier
Renal denervationRecent clinical studies have demonstrated that catheter-based renal sympathetic nerve ablation is safe and effective in treating patients with resistant hypertension. However, there is limited data on its safety and efficacy in patients with Chronic Kidney Disease. The investigators hypothesize that catheter-based renal sympathetic nerve ablation is safe and effective in the treatment of resistant hypertension in patients with Chronic Kidney Disease.	Hypertension	À vérifier	À vérifier	Singapore	À vérifier
Renal denervationRecent clinical studies have demonstrated that catheter-based renal sympathetic nerve ablation is safe and effective in treating patients with resistant hypertension. However, there is limited data on its safety and efficacy in patients with Chronic Kidney Disease. The investigators hypothesize that catheter-based renal sympathetic nerve ablation is safe and effective in the treatment of resistant hypertension in patients with Chronic Kidney Disease.	Hypertension	À vérifier	À vérifier	Singapore	À vérifier
Renal denervationRecent clinical studies have demonstrated that catheter-based renal sympathetic nerve ablation is safe and effective in treating patients with resistant hypertension. However, there is limited data on its safety and efficacy in patients with Chronic Kidney Disease. The investigators hypothesize that catheter-based renal sympathetic nerve ablation is safe and effective in the treatment of resistant hypertension in patients with Chronic Kidney Disease.	Hypertension	À vérifier	À vérifier	Sweden	À vérifier
EUSRA RFA needleThis study aims to evaluate the safety and efficacy of new ablation catheter developed by MEDICAL TAEWOONG for the treatment of pancreatic neoplasm (pancreatic adenocarcinoma or neuroendocrine tumour). The ablation is performed using EUSRA needle and radio frequency waves under ultrasound imaging. The subject who will be recruited into this study are patients who are deemed as non-surgical candidates.	Cancer	Non applicable	À vérifier	Singapore	À vérifier

Essais cliniques

3

Molécule	Indication / population	Phase	NCT	Titre	Statut
EUSRA RFA needle	Cancer	Non applicable	NCT03435770	Evaluation of Safety and Feasibility of EUS-guided RFA for Solid Pancreatic Neoplasms	UNKNOWN
Renal denervation	Hypertension	À vérifier	NCT04722159	Clinical Outcome of Patients With Resistant Hypertension Undergoing Renal Denervation	UNKNOWN
Renal denervation	Hypertension	À vérifier	NCT01747382	Renal Denervation for Treatment of Resistant Hypertension in Patients With Chronic Kidney Disease	NO_LONGER_AVAILABLE

Publications

4

Molécule	Indication / population	Titre	Journal	Date
Renal denervation		Effects of sympathomodulation on pulse wave properties in heart failure with preserved ejection fraction.	Clinical research in cardiology : official journal of the German Cardiac Society
Renal denervation		The onset of hypertension in metabolic syndrome is independent of renal sympathetic innervation.	Life science alliance
Renal denervation		Cardiometabolic Multimorbidity and Sympathetic Overactivity: Translational Rationale for Combined Hepatic-Renal Denervation.	JACC. Asia
Renal denervation		A Vagal-Renal-Splenic Reflex Suppresses Renal Sympathetic Nerve Activity and Preserves Kidney Function After Ischemic Injury.	Journal of the American Society of Nephrology : JASN