Traitements2programmes
Essais1liés
Publications1liées
SourceDBlocale

Traitements

2
MoléculeIndication / populationPhaseObjectifPaysRésultat
GC203 TILThis study is to investigate the safety and efficacy of gene-edited tumor infiltrating lymphocyte (GC203 TIL) therapy in patients with pancreatic ductal adenocarcinoma. Gene-edited TILs are expanded from tumor resections or biopsies and infused i.v. into the patient after NMA lymphodepletion treatment with hydroxychloroquine(600mg,single-dose) and cyclophosphamide. Cancer Phase 1 À vérifier China À vérifier
GC203 TILThis study is to investigate the safety and efficacy of gene-edited tumor infiltrating lymphocyte (GC203 TIL) therapy in patients with pancreatic ductal adenocarcinoma. Gene-edited TILs are expanded from tumor resections or biopsies and infused i.v. into the patient after NMA lymphodepletion treatment with hydroxychloroquine(600mg,single-dose) and cyclophosphamide. Cancer Phase 1 À vérifier China À vérifier

Essais cliniques

1
MoléculeIndication / populationPhaseNCTTitreStatut
GC203 TIL Cancer Phase 1 NCT06828328 A Study of GC203 TIL in PDCA (RJ) RECRUITING

Publications

1
MoléculeIndication / populationTitreJournalDate
GC203 TIL PiggyBac-engineered membrane-bound IL-7 TILs combined with anti-PD-1 antibody demonstrates efficacy in recurrent ovarian cancer: a first-in-human phase 1 trial. Clinical cancer research : an official journal of the American Association for Cancer Research