Second Affiliated Hospital, School of Medicine, Zhejiang University

Traitements7programmes

Essais4liés

Publications21liées

SourceDBlocale

Traitements

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
18F-FDGThis retrospective study aimed to develop a new approach for automatic localization of epilepsy foci in children with epilepsy.	Cancer, Épilepsie	À vérifier	À vérifier	China	À vérifier
18F-FDG PET Imaging Analysis of Antiepileptic Drug Response in BECTSThis original article is a novel investigation on the metabolic characteristics of different patterns of antiepileptic drug (AED) responses in benign epilepsy with centrotemporal spikes (BECTS) patients using 18F-FDG PET imaging. In this study, we demonstrated remitting-relapsing group showed more widespread hypo-metabolism regions than AED responders. Results indicated that metabolic differences had the ability to distinguish the remitting-relapsing patients from AED responders. 18F-FDG PET could be used as a marker to infer the current seizure activity of BECTS. We think that the established hybrid model based on PET and clinical features may be a critical reference for better personalized medication in patients with BECTS.	Épilepsie	À vérifier	À vérifier	China	À vérifier
Carbidopa and Levodopa Controlled Release TabletsThe main goal of PD research is to develop disease-modifying drugs to delay or prevent the underlying neurodegenerative process. Levodopa, as the gold standard for PD treatment, is associated with the occurrence of motor complications. Many previous studies have confirmed that Stalevo can reduce the side effects of levodopa alone. Moreover, the effects of Stalevo on the treatment of PD patients have been extensively studied, but the efficacy of Stalevo in early PD patients has been less studied. Therefore, it is necessary to further study the treatment of early PD with Stalevo, and observe whether increasing the number of medication can reduce the occurrence of dyskinesis. The research results will help to deepen the understanding of Stalevo in the treatment of early PD and its clinical efficacy.	Parkinson	Phase 4	À vérifier	China	À vérifier
StalevoThe main goal of PD research is to develop disease-modifying drugs to delay or prevent the underlying neurodegenerative process. Levodopa, as the gold standard for PD treatment, is associated with the occurrence of motor complications. Many previous studies have confirmed that Stalevo can reduce the side effects of levodopa alone. Moreover, the effects of Stalevo on the treatment of PD patients have been extensively studied, but the efficacy of Stalevo in early PD patients has been less studied. Therefore, it is necessary to further study the treatment of early PD with Stalevo, and observe whether increasing the number of medication can reduce the occurrence of dyskinesis. The research results will help to deepen the understanding of Stalevo in the treatment of early PD and its clinical efficacy.	Parkinson	Phase 4	À vérifier	China	À vérifier
18F-FDGThis retrospective study aimed to develop a new approach for automatic localization of epilepsy foci in children with epilepsy.	Épilepsie	À vérifier	À vérifier	China	À vérifier
StalevoThe main goal of PD research is to develop disease-modifying drugs to delay or prevent the underlying neurodegenerative process. Levodopa, as the gold standard for PD treatment, is associated with the occurrence of motor complications. Many previous studies have confirmed that Stalevo can reduce the side effects of levodopa alone. Moreover, the effects of Stalevo on the treatment of PD patients have been extensively studied, but the efficacy of Stalevo in early PD patients has been less studied. Therefore, it is necessary to further study the treatment of early PD with Stalevo, and observe whether increasing the number of medication can reduce the occurrence of dyskinesis. The research results will help to deepen the understanding of Stalevo in the treatment of early PD and its clinical efficacy.	Parkinson	Phase 4	À vérifier	China	À vérifier
18F-FDG PET Imaging Analysis of Antiepileptic Drug Response in BECTSThis original article is a novel investigation on the metabolic characteristics of different patterns of antiepileptic drug (AED) responses in benign epilepsy with centrotemporal spikes (BECTS) patients using 18F-FDG PET imaging. In this study, we demonstrated remitting-relapsing group showed more widespread hypo-metabolism regions than AED responders. Results indicated that metabolic differences had the ability to distinguish the remitting-relapsing patients from AED responders. 18F-FDG PET could be used as a marker to infer the current seizure activity of BECTS. We think that the established hybrid model based on PET and clinical features may be a critical reference for better personalized medication in patients with BECTS.	Épilepsie	À vérifier	À vérifier	China	À vérifier

Essais cliniques

Molécule	Indication / population	Phase	NCT	Titre	Statut
18F-FDG PET Imaging Analysis of Antiepileptic Drug Response in BECTS	Épilepsie	À vérifier	NCT04357236	18F-FDG PET Imaging Analysis of Antiepileptic Drug Response in BECTS	COMPLETED
UX-GIP001	Épilepsie	Phase 1	NCT07244328	Exploratory Study of UX-GIP001 Cell Therapy in Adult Patients With Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE)	RECRUITING
Stalevo	Parkinson	Phase 4	NCT04952194	Clinical Study of Stalevo in the Treatment of Early Parkinson's Disease	UNKNOWN
18F-FDG	Épilepsie	À vérifier	NCT04725162	Epileptogenic Focus Localization for Children With Epilepsy Using 18F-FDG PET Molecular Imaging	COMPLETED

Publications

Molécule	Titre	Journal
18F-FDG	Unveiling the unexpected: Skeletal sarcoidosis with an extraosseous soft-tissue mass in the ligamentous portion of sacroiliac joint.	Radiology case reports
18F-FDG	Multimodality imaging features of primary mammary angiosarcoma: a case report with delayed osseous metastases.	Radiology case reports
Stalevo	Resolving spectral overlaps in Anti-Parkinson drug combinations: a green spectrophotometric approach for entacapone determination.	BMC chemistry
18F-FDG	Development and Validation of a Novel Geriatric Risk Score for Prognostication in Older Patients With Hodgkin Lymphoma: A Multicenter Retrospective Study.	American journal of hematology
18F-FDG	A Diagnostic Dilemma in a Breast Cancer Patient on Tamoxifen: Perihepatic Endometriosis Masquerading as Metastatic Disease.	International medical case reports journal
18F-FDG	Stage-dependent performance and molecular subtype-specific relapse patterns on same-session [18F]FDG PET/contrast-enhanced CT in breast cancer.	European journal of nuclear medicine and molecular imaging
18F-FDG	FDG-PET in Traumatic Brain Injury and Postconcussive Sequelae.	PET clinics
18F-FDG	PET/CT Normal Variants and Pitfalls in Paediatric Disorders.	Seminars in nuclear medicine
18F-FDG	Effect of Low-Dose Rivaroxaban Plus Aspirin on 18F-FDG PET/CT-Detectable Carotid Plaque Inflammation: A Randomised Trial.	European heart journal. Cardiovascular Imaging
18F-FDG	Prostatic incidental uptake on PET/CT: an updated systematic review and meta-analysis of prevalence and malignancy risk.	Frontiers in oncology
18F-FDG	The efficacy assessment of neoadjuvant TKI and anti-PD-1 combination therapy followed by surgery for hepatocellular carcinoma using PERCIST criteria: an exploratory study.	European journal of radiology
18F-FDG	Strict carbohydrate restriction enables volume-based FDG-PET/CT to outperform SUVmax for risk stratification in cardiac sarcoidosis.	International journal of cardiology. Heart & vasculature
Carbidopa and Levodopa Controlled Release Tablets	Formulation and clinical evaluation of carbidopa/levodopa oral solution for the treatment of sepiapterin reductase deficiency.	European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Carbidopa and Levodopa Controlled Release Tablets	Foslevodopa/Foscarbidopa: A Review in Advanced Parkinson's Disease.	CNS drugs
18F-FDG	Cross-modal fusion of cytomorphology and F-FDG PET/CT for non-invasive bone marrow immune microenvironment decoding in multiple myeloma.	Frontiers in immunology
18F-FDG	A real-world decision tree model based on ¹⁸F-FDG PET/CT Z scores and Mini-Mental State Examination for differentiating mild cognitive impairment from clinically diagnosed Alzheimer disease.	Annals of nuclear medicine
Stalevo	In brief: New warnings for carbidopa/levodopa products.	The Medical letter on drugs and therapeutics
Stalevo	Pharmacokinetics and Tolerability of Entacapone, Levodopa, and Carbidopa Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Four-Period Crossover Study Under Fasting and Fed Conditions.	Clinical pharmacology in drug development
18F-FDG	Disseminated infection with osseous involvement in anti-interferon-γ autoantibody-associated adult-onset immunodeficiency: a case report and literature review.	Frontiers in immunology
18F-FDG	Divergent Radiomolecular Phenotype of Spindle Cell Lipoma: Intense 68Ga-PSMA Uptake in a Lesion With Mild 18F-FDG Avidity.	Clinical nuclear medicine
18F-FDG	Diagnostic performance of [18F]FDG PET/CT in large vessel vasculitis management: an umbrella review.	The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...