Rush University Medical Center — Biomedical Watch V2

Traitements6programmes

Essais3liés

Publications4liées

SourceDBlocale

Traitements

6

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
ASSUAGE ProtocolThe investigators developed a modified regadenoson nuclear stress test of the heart that incorporates an aminophylline injection following regadenoson (The ASSUAGE protocol). The modified (ASSUAGE) protocol has been associated with fewer side effects and was better tolerated by patients. This study will investigate whether the modified regadenoson stress protocol (ASSUAGE) produces blood flow pattern to the heart similar to that of a standard regadenoson stress protocol. In proven to be the case, the ASSUAGE protocol has the potential to be used on a wide scale instead of the current standard protocol.	SEP	Phase 4	À vérifier	United States	À vérifier
In-Home Care for Patients With Parkinson's DiseaseAdvanced Parkinson's Disease is a debilitating, costly, and understudied condition. Improving access to comprehensive, specialized, in-home patient care and caregiver support offers the potential to minimize the downward spiral of morbidity and preventable healthcare utilization. The aim of this study is to test whether and to what degree an interdisciplinary home visit program, with and without peer mentoring for caregivers, will improve patient- and caregiver-reported outcomes and reduce healthcare costs when compared with usual care in advanced Parkinson's Disease.	Parkinson	NA	À vérifier	United States	À vérifier
Mobilizing Community Hypertension Access PilotThe Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted community settings on the West and South Sides of Chicago. Adults with uncontrolled hypertension will be identified and enrolled through community-based organizations, where a mobile clinical team-including community health workers, a pharmacist, and a registered nurse-will provide blood pressure screening, medication management, health education, and care coordination over a 3-month period. The study will assess participant engagement and acceptability, changes in systolic blood pressure. This pilot aims to address disparities in hypertension control by improving access to care in underserved communities and informing scalable, community-based models of chronic disease management.	Hypertension	NA	À vérifier	United States	À vérifier
Mobilizing Community Hypertension Access PilotThe Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted community settings on the West and South Sides of Chicago. Adults with uncontrolled hypertension will be identified and enrolled through community-based organizations, where a mobile clinical team-including community health workers, a pharmacist, and a registered nurse-will provide blood pressure screening, medication management, health education, and care coordination over a 3-month period. The study will assess participant engagement and acceptability, changes in systolic blood pressure. This pilot aims to address disparities in hypertension control by improving access to care in underserved communities and informing scalable, community-based models of chronic disease management.	Hypertension	NA	À vérifier	United States	À vérifier
In-Home Care for Patients With Parkinson's DiseaseAdvanced Parkinson's Disease is a debilitating, costly, and understudied condition. Improving access to comprehensive, specialized, in-home patient care and caregiver support offers the potential to minimize the downward spiral of morbidity and preventable healthcare utilization. The aim of this study is to test whether and to what degree an interdisciplinary home visit program, with and without peer mentoring for caregivers, will improve patient- and caregiver-reported outcomes and reduce healthcare costs when compared with usual care in advanced Parkinson's Disease.	Parkinson	NA	À vérifier	United States	À vérifier
ASSUAGE ProtocolThe investigators developed a modified regadenoson nuclear stress test of the heart that incorporates an aminophylline injection following regadenoson (The ASSUAGE protocol). The modified (ASSUAGE) protocol has been associated with fewer side effects and was better tolerated by patients. This study will investigate whether the modified regadenoson stress protocol (ASSUAGE) produces blood flow pattern to the heart similar to that of a standard regadenoson stress protocol. In proven to be the case, the ASSUAGE protocol has the potential to be used on a wide scale instead of the current standard protocol.	SEP	Phase 4	À vérifier	United States	À vérifier

Essais cliniques

3

Molécule	Indication / population	Phase	NCT	Titre	Statut
ASSUAGE Protocol	SEP	Phase 4	NCT01655524	ASSUAGE-MPI — The Impact of the Routine Aminophylline Administration Following Regadenoson Stress on SPECT Myocardial Perfusion	WITHDRAWN
In-Home Care for Patients With Parkinson's Disease	Parkinson	NA	NCT03189459	In-Home Care for Patients With Parkinson's Disease	COMPLETED
Mobilizing Community Hypertension Access Pilot	Hypertension	NA	NCT07547345	Mobilizing Community Hypertension Access Pilot	RECRUITING

Publications

4

Molécule	Indication / population	Titre	Journal	Date
In-Home Care for Patients With Parkinson's Disease		Parkinsonian syndromes in institutionalized older adults in the French Caribbean: Clinical characteristics and one-year mortality.	Parkinsonism & related disorders
Mobilizing Community Hypertension Access Pilot		Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016.	BMC health services research
In-Home Care for Patients With Parkinson's Disease		Performance of the SmartMe&You serious video games for home telemonitoring is related to cognitive status and resting-state electroencephalographic markers in healthy and Parkinson's disease participants.	GeroScience
In-Home Care for Patients With Parkinson's Disease		Quality management and specifications of multidisciplinary Parkinson's disease management: an expert opinion.	Journal of neural transmission (Vienna, Austria : 1996)