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Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Traitements, essais et publications liés.
Traitements14programmes
Essais6liés
Publications20liées
SourceDBlocale
Traitements
14| Molécule | Indication / population | Phase | Objectif | Pays | Résultat |
|---|---|---|---|---|---|
| eletriptanTo assess the safety and efficacy of eletriptan for the treatment of migraine in subjects who had not been adequately treated with non-steroidal antiinflammatory drugs (NSAIDs) | Migraine | Phase 4 | Immunomodulation | Turkey (Türkiye) | À vérifier |
| Eletriptan 20 mgTo confirm the efficacy of three dose levels of oral eletriptan relative to placebo in relieving symptoms of acute migraine and to further explore the dose response relationship of eletriptan. | Migraine | Phase 3 | Traitement symptomatique | À vérifier | |
| Eletriptan 40 mgThe objective of this study was to compare the efficacy, toleration and safety of eletriptan 40mg and 80mg, with sumatriptan 25mg and 50mg, and placebo when given orally to subjects with an acute migraine. | Migraine | Phase 3 | À vérifier | À vérifier | |
| Eletriptan 80 mgThe objective of this study was to compare the efficacy, toleration and safety of eletriptan 40mg and 80mg, with sumatriptan 25mg and 50mg, and placebo when given orally to subjects with an acute migraine. | Migraine | Phase 3 | À vérifier | À vérifier | |
| pregabalinApproximately 30% percent of subjects with partial seizures are refractory to treatment with single or combination antiepileptic drugs. The present study will compare the efficacy of two different dosages of pregabalin CR dosed once daily as compared to placebo, when used as adjunctive therapy in subjects requiring adjunctive therapy for partial onset epilepsy, using a randomized, parallel group design. | Épilepsie, SEP | Phase 3 | À vérifier | United States, Argentina, Bosnia and Herzegovina, Bulgaria, Czechia, Germany, Hong Kong, Hungary, … | À vérifier |
| Sumatriptan 100 mgThis proof-of-concept study compares side-by-side low-dose naltrexone and acetaminophen combination to sumatriptan in the acute treatment of migraine. | Migraine | Phase 3 | À vérifier | United States | À vérifier |
| Sumatriptan 25 mgThe objective of this study was to compare the efficacy, toleration and safety of eletriptan 40mg and 80mg, with sumatriptan 25mg and 50mg, and placebo when given orally to subjects with an acute migraine. | Migraine | Phase 3 | À vérifier | À vérifier | |
| Sumatriptan 50 mgThe objective of this study was to compare the efficacy, toleration and safety of eletriptan 40mg and 80mg, with sumatriptan 25mg and 50mg, and placebo when given orally to subjects with an acute migraine. | Migraine | Phase 3 | À vérifier | À vérifier | |
| pregabalinApproximately 30% percent of subjects with partial seizures are refractory to treatment with single or combination antiepileptic drugs. The present study will compare the efficacy of two different dosages of pregabalin CR dosed once daily as compared to placebo, when used as adjunctive therapy in subjects requiring adjunctive therapy for partial onset epilepsy, using a randomized, parallel group design. | Épilepsie | Phase 3 | À vérifier | United States, Argentina, Bosnia and Herzegovina, Bulgaria, Czechia, Germany, Hong Kong, Hungary, India, Malaysia, Mexico, Poland, Puerto Rico, Romania, Russia, Serbia, Singapore, Thailand | À vérifier |
| pregabalinApproximately 30% percent of subjects with partial seizures are refractory to treatment with single or combination antiepileptic drugs. The present study will compare the efficacy of two different dosages of pregabalin CR dosed once daily as compared to placebo, when used as adjunctive therapy in subjects requiring adjunctive therapy for partial onset epilepsy, using a randomized, parallel group design. | Épilepsie | Phase 3 | À vérifier | United States, Canada | À vérifier |
| eletriptanTo assess the safety and efficacy of eletriptan for the treatment of migraine in subjects who had not been adequately treated with non-steroidal antiinflammatory drugs (NSAIDs) | Migraine | Phase 4 | Immunomodulation | Turkey (Türkiye) | À vérifier |
| Eletriptan 40 mgThe objective of this study was to compare the efficacy, toleration and safety of eletriptan 40mg and 80mg, with sumatriptan 25mg and 50mg, and placebo when given orally to subjects with an acute migraine. | Migraine | Phase 3 | À vérifier | À vérifier | |
| Eletriptan 20 mgTo confirm the efficacy of three dose levels of oral eletriptan relative to placebo in relieving symptoms of acute migraine and to further explore the dose response relationship of eletriptan. | Migraine | Phase 3 | Traitement symptomatique | À vérifier | |
| Eletriptan 40 mgThe objective of this study was to compare the efficacy, toleration and safety of eletriptan 40mg and 80mg, with sumatriptan 25mg and 50mg, and placebo when given orally to subjects with an acute migraine. | Migraine | Phase 3 | À vérifier | À vérifier |
Essais cliniques
6| Molécule | Indication / population | Phase | NCT | Titre | Statut |
|---|---|---|---|---|---|
| Eletriptan 40 mg | Migraine | Phase 3 | NCT01986088 | Eletriptan vs Sumatriptan: A Double-blind, Placebo-controlled, Multiple Migraine Attack Study | COMPLETED |
| Eletriptan 20 mg | Migraine | Phase 3 | NCT01978496 | Efficacy, Safety, and Tolerability of Oral Eletriptan for Treatment of Acute Migraine | COMPLETED |
| Eletriptan 40 mg | Migraine | Phase 3 | NCT01986270 | Comparative Study of Oral Eletriptan (40mg and 80mg), Oral Sumatriptan (25mg and 50mg) and Placebo | COMPLETED |
| eletriptan | Migraine | Phase 4 | NCT00634985 | Safety and Efficacy of Eletriptan for the Treatment of Migraine in Subjects Unsuccessfully Treated With Nonsteroidal Anti-inflammatory Drugs | COMPLETED |
| pregabalin | Épilepsie | Phase 3 | NCT00141388 | To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures | COMPLETED |
| pregabalin | Épilepsie | Phase 3 | NCT01262677 | Once-A-Day Pregabalin For Partial Seizures | COMPLETED |
Publications
20| Molécule | Indication / population | Titre | Journal | Date |
|---|---|---|---|---|
| Sumatriptan 50 mg | Onset of action in placebo-controlled migraine attacks trials: A literature review and recommendation. | Cephalalgia : an international journal of headache | ||
| Sumatriptan 50 mg | Bergapten Attenuates Nitroglycerin-Induced Migraine Headaches through Inhibition of Oxidative Stress and Inflammatory Mediators. | ACS chemical neuroscience | ||
| Sumatriptan 50 mg | Rizatriptan as an Over-the-Counter Triptan in the Treatment of Migraine Attacks. | Pain and therapy | ||
| Eletriptan 20 mg | Economic analysis of triptan therapy for acute migraine: a Medicaid perspective. | Pharmacotherapy | ||
| Eletriptan 20 mg | Perimenstrual eletriptan prevents menstrual migraine: an open-label study. | Headache | ||
| Eletriptan 20 mg | Comparing the efficacy of eletriptan for migraine in women during menstrual and non-menstrual time periods: a pooled analysis of randomized controlled trials. | Headache | ||
| eletriptan | Novel Application of UHPLC-MS, HRMS, and 2D-NMR for Structural Elucidation of Eletriptan Hydrobromide and Its Novel Degradation Products. | Biomedical chromatography : BMC | ||
| pregabalin | Prescribing Patterns of Gabapentinoids in Patients with Chronic Obstructive Pulmonary Disorder. | COPD | ||
| pregabalin | Gabapentinoids and unexplained death in general practice: Case series and feasibility study arising from a critical incident. | The European journal of general practice | ||
| pregabalin | Association Between the Use of Gabapentinoids and Exacerbations of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis. | Current therapeutic research, clinical and experimental | ||
| pregabalin | An NLRP3 inflammasome inhibitor evoked dose-dependent anti-allodynia in the hindpaws of a rat model of chemotherapy-induced peripheral neuropathy. | Inflammopharmacology | ||
| pregabalin | Comparative Effectiveness, Safety, and Costs of Gabapentinoids in Older Adults With Long-Term Opioid Use. | Journal of the American Geriatrics Society | ||
| eletriptan | Eletriptan HBr-loaded solid lipid nanoparticle-integrated microneedles: a targeted and minimally invasive approach for migraine management. | Journal of drug targeting | ||
| eletriptan | Chronic Migraine Resistance: A Case Report Highlights an Overlooked Factors in Family Medicine Clinics. | Healthcare (Basel, Switzerland) | ||
| pregabalin | Vitamin B12 and pregabalin combination restored brain waves dynamics and behavior in chronic unpredictable mild stress (CUMS) model of depression. | Naunyn-Schmiedeberg's archives of pharmacology | ||
| pregabalin | Comparison of Ketamine and Pregabalin on Postoperative Opioid Usage and Pain Management in Spinal Fusion: Systematic Review and Network Meta-analysis. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia | ||
| pregabalin | The effect of pregabalin on pain and function in knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. | Inflammopharmacology | ||
| pregabalin | Once-Nightly Pregabalin for Co-Occurring Nightmares, Poor Sleep, and Headaches: A Case Series. | Nature and science of sleep | ||
| pregabalin | Management of Pain and Pruritus in Pediatric Recessive Dystrophic Epidermolysis Bullosa. | Clinical case reports | ||
| pregabalin | Pharmacological and non-pharmacological therapies for chronic pancreatitis pain: a narrative review. | Frontiers in physiology |