Traitements3programmes
Essais1liés
Publications5liées
SourceDBlocale

Traitements

3
MoléculeIndication / populationPhaseObjectifPaysRésultat
NXN-188NXN-188 Dihydrochloride is being developed as an immediate release oral product for the treatment of acute migraine. This study is being conducted to evaluate NXN-188 in subjects with a migraine history of aura. Migraine Phase 2 À vérifier United States À vérifier
sumatriptan succinateNXN-188 Dihydrochloride is being developed as an immediate release oral product for the treatment of acute migraine. This study is being conducted to evaluate NXN-188 in subjects with a migraine history of aura. Migraine Phase 2 À vérifier United States À vérifier
NXN-188NXN-188 Dihydrochloride is being developed as an immediate release oral product for the treatment of acute migraine. This study is being conducted to evaluate NXN-188 in subjects with a migraine history of aura. Migraine Phase 2 À vérifier United States À vérifier

Essais cliniques

1
MoléculeIndication / populationPhaseNCTTitreStatut
NXN-188 Migraine Phase 2 NCT00920686 Study of NXN 188 for the Treatment of Migraine With Aura COMPLETED

Publications

5
MoléculeIndication / populationTitreJournalDate
NXN-188 NXN-188, a selective nNOS inhibitor and a 5-HT1B/1D receptor agonist, inhibits CGRP release in preclinical migraine models. Cephalalgia : an international journal of headache
sumatriptan succinate Spatial metabolomics combined with MALDI-MSI unveils gut-brain axis mechanisms of angelica dahurica radix in migraine rats. Phytomedicine : international journal of phytotherapy and phytopharmacology
sumatriptan succinate Cellulose and Its Derivatives in Drug Delivery: Recent Advances and Applications. Pharmaceutics
NXN-188 Drugs targeting nitric oxide synthase for migraine treatment. Expert opinion on investigational drugs
NXN-188 The nitric oxide synthase inhibitor and serotonin-receptor agonist NXN-188 during the aura phase of migraine with aura: A randomized, double-blind, placebo-controlled cross-over study. Scandinavian journal of pain