Jewish General Hospital — Biomedical Watch V2

Traitements3programmes

Essais2liés

Publications3liées

SourceDBlocale

Traitements

3

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Irreversible Electroporation (IRE)Most prostate cancer treatment research in the last decade has been focused on trying to improve quality of life, while maintaining a high level of cancer control. However, the concept of Focal treatment is proposed as an intermediate option between active surveillance and treatment of the whole prostate. Focal ablation aims to efficiently treat the localized cancer while reducing complications related to standard treatments, including the risks of incontinence and impotence. Focal Irreversible Electroporation (IRE) delivered by NanoKnife System is composed of the NanoKnife Generator and NanoKnife Single Electrode Probes. With IRE, an electrical current is delivered between a pair of probes in a series of pulses. These pulses create irreversible pores in cell membranes and lead to cell death which allow for only the tissue between these probes being destroyed. The aim of this study is to analyze the safety and efficacy of transperineal IRE treatments in intermediate risk anteriorly localized prostate cancer patients.	Cancer	Non applicable	À vérifier	Netherlands	À vérifier
Irreversible Electroporation (IRE)Most prostate cancer treatment research in the last decade has been focused on trying to improve quality of life, while maintaining a high level of cancer control. However, the concept of Focal treatment is proposed as an intermediate option between active surveillance and treatment of the whole prostate. Focal ablation aims to efficiently treat the localized cancer while reducing complications related to standard treatments, including the risks of incontinence and impotence. Focal Irreversible Electroporation (IRE) delivered by NanoKnife System is composed of the NanoKnife Generator and NanoKnife Single Electrode Probes. With IRE, an electrical current is delivered between a pair of probes in a series of pulses. These pulses create irreversible pores in cell membranes and lead to cell death which allow for only the tissue between these probes being destroyed. The aim of this study is to analyze the safety and efficacy of transperineal IRE treatments in intermediate risk anteriorly localized prostate cancer patients.	Cancer	Non applicable	À vérifier		À vérifier
Irreversible Electroporation (IRE)Most prostate cancer treatment research in the last decade has been focused on trying to improve quality of life, while maintaining a high level of cancer control. However, the concept of Focal treatment is proposed as an intermediate option between active surveillance and treatment of the whole prostate. Focal ablation aims to efficiently treat the localized cancer while reducing complications related to standard treatments, including the risks of incontinence and impotence. Focal Irreversible Electroporation (IRE) delivered by NanoKnife System is composed of the NanoKnife Generator and NanoKnife Single Electrode Probes. With IRE, an electrical current is delivered between a pair of probes in a series of pulses. These pulses create irreversible pores in cell membranes and lead to cell death which allow for only the tissue between these probes being destroyed. The aim of this study is to analyze the safety and efficacy of transperineal IRE treatments in intermediate risk anteriorly localized prostate cancer patients.	Cancer	Non applicable	À vérifier	Netherlands	À vérifier

Essais cliniques

2

Molécule	Indication / population	Phase	NCT	Titre	Statut
Irreversible Electroporation (IRE)	Cancer	Non applicable	NCT02791503	CROSSFIRE Trial: Comparing the Efficacy of Irreversible Electroporation With Radiotherapy	COMPLETED
Irreversible Electroporation (IRE)	Cancer	Non applicable	NCT05512663	Safety and Efficacy Evaluation of Transperineal Irreversible Electroporation (IRE) of Anterior Prostate Cancer	UNKNOWN

Publications

3

Molécule	Indication / population	Titre	Journal	Date
Irreversible Electroporation (IRE)		Prostate imaging after focal ablation scoring after irreversible electroporation treatment in localized prostate cancer: Diagnostic accuracy and inter-reader agreement.	European journal of radiology
Irreversible Electroporation (IRE)		Contrast-enhanced ultrasound as a problem-solving tool and irreversible electroporation for a perivascular/peribiliary segment IVs colorectal liver metastasis: a case report.	Radiology case reports
Irreversible Electroporation (IRE)		Oncologic and functional outcomes of novel focal therapy methods for low-risk to intermediate-risk prostate cancer.	Current opinion in urology