Istanbul University — Biomedical Watch V2

Traitements5programmes

Essais2liés

Publications8liées

SourceDBlocale

Traitements

5

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Capsaicin Topical CreamThe goal of this clinical trial is to compare the effectiveness and safety of topical capsaicin cream and topical diclofenac gel in women with chronic temporomandibular joint-related pain. The main questions it aims to answer are: * Does topical capsaicin reduce pain intensity more effectively than topical diclofenac? * Do the treatments improve jaw function, pressure pain threshold, and neuropathic pain symptoms? Researchers will compare topical capsaicin cream with topical diclofenac gel to evaluate differences in pain relief and functional improvement. Participants will: * Apply the assigned topical medication four times daily for 7 days * Attend clinical examinations and pain assessments at baseline, Day 8, and Month 1 * Complete pain-related questionnaires and functional jaw measurements during follow-up visits	Myopathies	NA	Traitement symptomatique	Turkey (Türkiye)	À vérifier
Diclofenac 1% TopicalThe goal of this clinical trial is to compare the effectiveness and safety of topical capsaicin cream and topical diclofenac gel in women with chronic temporomandibular joint-related pain. The main questions it aims to answer are: * Does topical capsaicin reduce pain intensity more effectively than topical diclofenac? * Do the treatments improve jaw function, pressure pain threshold, and neuropathic pain symptoms? Researchers will compare topical capsaicin cream with topical diclofenac gel to evaluate differences in pain relief and functional improvement. Participants will: * Apply the assigned topical medication four times daily for 7 days * Attend clinical examinations and pain assessments at baseline, Day 8, and Month 1 * Complete pain-related questionnaires and functional jaw measurements during follow-up visits	Myopathies	NA	Traitement symptomatique	Turkey (Türkiye)	À vérifier
Effectiveness of a Home-Based Exercise Program Supported by Self-Management Education in People With Parkinson DiseaseThis randomized, assessor-blinded clinical trial evaluates whether a structured self-management education and home exercise program improves balance, walking capacity, fall-related concerns, upper-extremity dexterity, and quality of life in adults with Parkinson disease. Fifty-five participants aged 45-80 years will be randomized to an intervention or control arm. Outcomes will be assessed at baseline, after the 8-week intervention, and at Week 16. The primary outcome is the Berg Balance Scale.	Parkinson	Non applicable	À vérifier	Turkey (Türkiye)	À vérifier
Capsaicin Topical CreamThe goal of this clinical trial is to compare the effectiveness and safety of topical capsaicin cream and topical diclofenac gel in women with chronic temporomandibular joint-related pain. The main questions it aims to answer are: * Does topical capsaicin reduce pain intensity more effectively than topical diclofenac? * Do the treatments improve jaw function, pressure pain threshold, and neuropathic pain symptoms? Researchers will compare topical capsaicin cream with topical diclofenac gel to evaluate differences in pain relief and functional improvement. Participants will: * Apply the assigned topical medication four times daily for 7 days * Attend clinical examinations and pain assessments at baseline, Day 8, and Month 1 * Complete pain-related questionnaires and functional jaw measurements during follow-up visits	Myopathies	NA	Traitement symptomatique	Turkey (Türkiye)	À vérifier
Effectiveness of a Home-Based Exercise Program Supported by Self-Management Education in People With Parkinson DiseaseThis randomized, assessor-blinded clinical trial evaluates whether a structured self-management education and home exercise program improves balance, walking capacity, fall-related concerns, upper-extremity dexterity, and quality of life in adults with Parkinson disease. Fifty-five participants aged 45-80 years will be randomized to an intervention or control arm. Outcomes will be assessed at baseline, after the 8-week intervention, and at Week 16. The primary outcome is the Berg Balance Scale.	Parkinson	Non applicable	À vérifier	Turkey (Türkiye)	À vérifier

Essais cliniques

2

Molécule	Indication / population	Phase	NCT	Titre	Statut
Effectiveness of a Home-Based Exercise Program Supported by Self-Management Education in People With Parkinson Disease	Parkinson	Non applicable	NCT07817862	Effectiveness of a Home-Based Exercise Program Supported by Self-Management Education in People With Parkinson Disease	NOT_YET_RECRUITING
Capsaicin Topical Cream	Myopathies	NA	NCT07598994	Topical Capsaicin Versus Diclofenac for Chronic Temporomandibular Joint-Related Pain	COMPLETED

Publications

8

Molécule	Indication / population	Titre	Journal	Date
Diclofenac 1% Topical		Capsaicin and diclofenac coloaded nanoemulsion gel optimized by quality by design approach of for the treatment of rheumatoid arthritis.	Therapeutic delivery
Diclofenac 1% Topical		Hyaluronic acid nanoparticle as drug delivery carrier for the treatment of allergic conjunctivitis.	Bio-medical materials and engineering
Capsaicin Topical Cream		Successful Management of Refractory Cannabinoid Hyperemesis Syndrome With Topical Capsaicin: A Case Report With Proposed Mechanism of Action and Literature Review.	Clinical medicine insights. Case reports
Capsaicin Topical Cream		Topical resiniferatoxin for the treatment of vestibulodynia: a prospective observational trial.	AJOG global reports
Diclofenac 1% Topical		A double-blinded randomized clinical trial: Topical Sahasthara extract diclofenac for treating primary knee osteoarthritis using microemulsions as a topical delivery system.	Journal of traditional and complementary medicine
Diclofenac 1% Topical		Baboon Syndrome Triggered by Diclofenac Potassium: A Case Report of Symmetrical Drug-Related Intertriginous and Flexural Exanthema.	Case reports in dermatology
Capsaicin Topical Cream		Non-Inferiority Study of Two Capsaicin Formulations for Painful Diabetic Neuropathy.	Life (Basel, Switzerland)
Capsaicin Topical Cream		Chronic pain after mastectomy: current knowledge and knowledge gaps.	Minerva anestesiologica