Traitements3programmes
Essais2liés
Publications2liées
SourceDBlocale

Traitements

3
MoléculeIndication / populationPhaseObjectifPaysRésultat
HER-096This study evaluates the safety and tolerability of HER-096 in healthy volunteer subjects by comparing the effects of active study treatment HER-096 to placebo (0.9% physiological saline). In addition, the pharmacokinetic profile of HER-096 in humans will be investigated. The investigational medicinal products will be administered as a single dose by subcutaneous injection. Parkinson Phase 1 À vérifier Finland À vérifier
HER-096This study evaluates the safety and tolerability of HER-096 in healthy volunteer subjects by comparing the effects of active study treatment HER-096 to placebo (0.9% physiological saline). In addition, the pharmacokinetic profile of HER-096 in humans will be investigated. The investigational medicinal products will be administered as a single dose by subcutaneous injection. Parkinson Phase 1 À vérifier Finland À vérifier
HER-096This study evaluates the safety and tolerability of HER-096 in healthy volunteer subjects by comparing the effects of active study treatment HER-096 to placebo (0.9% physiological saline). In addition, the pharmacokinetic profile of HER-096 in humans will be investigated. The investigational medicinal products will be administered as a single dose by subcutaneous injection. Parkinson Phase 1 À vérifier Finland À vérifier

Essais cliniques

2
MoléculeIndication / populationPhaseNCTTitreStatut
HER-096 Parkinson Phase 1 NCT06659562 Clinical Study of HER-096 in Healthy Volunteer Subjects and Patients With Parkinson's Disease COMPLETED
HER-096 Parkinson Phase 1 NCT05915247 Single Ascending Doses of HER-096 in Healthy Subjects COMPLETED

Publications

2
MoléculeIndication / populationTitreJournalDate
HER-096 Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson's disease. Neural regeneration research
HER-096 Cerebral dopamine neurotrophic factor and its functional fragments induce calcium signal through sigma-1 receptor and protect neurons against glutamate-induced excitotoxicity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie