Traitements4programmes
Essais1liés
Publications12liées
SourceDBlocale

Traitements

4
MoléculeIndication / populationPhaseObjectifPaysRésultat
ET1402L1-ARTEMIS™ T cells -intra-hepatic arteryClinical study to evaluate safety (primary objectives) and efficacy (secondary objective) of ET1402L1-ARTEMIS™2 T cells in patients with alpha fetoprotein positive (AFP+ ) hepatocellular carcinoma (HCC). Cancer Phase 1 Immunomodulation China À vérifier
ET1402L1-ARTEMIS™ T cells -Intratumoral InjectionsClinical study to evaluate safety (primary objectives) and efficacy (secondary objective) of ET1402L1-ARTEMIS™2 T cells in patients with alpha fetoprotein positive (AFP+ ) hepatocellular carcinoma (HCC). Cancer Phase 1 Immunomodulation China À vérifier
ET1402L1-ARTEMIS™ T cells -IVClinical study to evaluate safety (primary objectives) and efficacy (secondary objective) of ET1402L1-ARTEMIS™2 T cells in patients with alpha fetoprotein positive (AFP+ ) hepatocellular carcinoma (HCC). Cancer Phase 1 Immunomodulation China À vérifier
ET1402L1-ARTEMIS™ T cells -IVClinical study to evaluate safety (primary objectives) and efficacy (secondary objective) of ET1402L1-ARTEMIS™2 T cells in patients with alpha fetoprotein positive (AFP+ ) hepatocellular carcinoma (HCC). Cancer Phase 1 Immunomodulation China À vérifier

Essais cliniques

1
MoléculeIndication / populationPhaseNCTTitreStatut
ET1402L1-ARTEMIS™ T cells -IV Cancer Phase 1 NCT03888859 ET1402L1-ARTEMIS™2 T Cells in Alpha Fetoprotein (AFP) Expressing Hepatocellular Carcinoma COMPLETED

Publications

12
MoléculeIndication / populationTitreJournalDate
ET1402L1-ARTEMIS™ T cells -Intratumoral Injections CCL19-armed oncolytic adenovirus synergizes with CCR7-expressing CAR-T cells to suppress ovarian tumor growth. International immunopharmacology
ET1402L1-ARTEMIS™ T cells -Intratumoral Injections Modulated electro-hyperthermia enhances tumor cell susceptibility to γδ T cell-mediated cytotoxicity and tumor infiltration in NOD/SCID xenograft models. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
ET1402L1-ARTEMIS™ T cells -Intratumoral Injections Prolonged intratumoral treatment with TLR7/8 agonist R848 regulates the tumor immune microenvironment resulting in enhanced antitumor activity. Cancer biology & therapy
ET1402L1-ARTEMIS™ T cells -IV Novel captopril-valproic acid platinum(IV) hybrids with potent antiproliferative and antimetastatic activities targeting fibrosis and DNA-repair. European journal of medicinal chemistry
ET1402L1-ARTEMIS™ T cells -IV Broad cross-T cell immunity between emerging SARS-CoV-2 serotypes waved by spike-signature mutations. Emerging microbes & infections
ET1402L1-ARTEMIS™ T cells -IV Immune evasion in locally advanced mismatch repair-deficient microsatellite instability-high colorectal cancer: Reduced T-cell infiltration and upregulation of epithelial IDO1 expression. Oncoimmunology
ET1402L1-ARTEMIS™ T cells -Intratumoral Injections Armed Oncolytic Myxoma Virus Induces Systemic Antitumor Immunity Against Solid Tumors in Immunocompetent Mice. Research square
ET1402L1-ARTEMIS™ T cells -Intratumoral Injections The closer, the better: intratumoral delivery of a thermoresponsive gemcitabine-loaded hydrogel in preclinical PDAC models. Drug delivery and translational research
ET1402L1-ARTEMIS™ T cells -intra-hepatic artery [Selective effectiveness of galactose-containing liposome IL-2 on liver lymphocytes]. Gan to kagaku ryoho. Cancer & chemotherapy
ET1402L1-ARTEMIS™ T cells -intra-hepatic artery In situ delivery of allogeneic natural killer cell (NK) combined with Cetuximab in liver metastases of gastrointestinal carcinoma: A phase I clinical trial. Oncoimmunology
ET1402L1-ARTEMIS™ T cells -IV Apatinib enhances targeted immunotherapy the IL-6-gp130-PI3K pathway in HER2-positive gastric cancer. Cancer biology & medicine
ET1402L1-ARTEMIS™ T cells -IV FGFR2 fusion-driven cholangiocarcinoma is characterized by a distinct neutrophil-enriched tumor microenvironment in a syngeneic murine model. JHEP reports : innovation in hepatology