First Affiliated Hospital, Sun Yat-Sen University — Biomedical Watch V2

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Traitements

2

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Variables Predicting Reintubation After Thymectomy in Patients With Myasthenia GravisMyasthenia gravis (MG) is an autoimmune disease that is characterized by muscle weakness and fatigue. The role of the thymus in MG has been suggested by the evidence that 10% to 15% of patients present with a thymoma and at least 60% with thymus hyperplasia or dysplasia.Beneficial effects of thymectomy in patients with MG have been described in 40% to 90%.Few studies have looked at the incidence of reintubation (not just within 24 hours after extubation), the factors associated with reintubation, and patient outcome. Premature extubation may lead to hypercarbia, hypoxemia, pulmonary hypertension, right heart failure, and myocardial ischemia. Additionally, it subjects the patient to the physical risks of reintubation, including esophageal intubation, laryngeal trauma, and pulmonary aspiration. The purpose of the present study was to determine the incidence of reintubation, the variables associated with reintubation, and patient outcome	Myasthénie	À vérifier	Traitement symptomatique	China	À vérifier
Variables Predicting Reintubation After Thymectomy in Patients With Myasthenia GravisMyasthenia gravis (MG) is an autoimmune disease that is characterized by muscle weakness and fatigue. The role of the thymus in MG has been suggested by the evidence that 10% to 15% of patients present with a thymoma and at least 60% with thymus hyperplasia or dysplasia.Beneficial effects of thymectomy in patients with MG have been described in 40% to 90%.Few studies have looked at the incidence of reintubation (not just within 24 hours after extubation), the factors associated with reintubation, and patient outcome. Premature extubation may lead to hypercarbia, hypoxemia, pulmonary hypertension, right heart failure, and myocardial ischemia. Additionally, it subjects the patient to the physical risks of reintubation, including esophageal intubation, laryngeal trauma, and pulmonary aspiration. The purpose of the present study was to determine the incidence of reintubation, the variables associated with reintubation, and patient outcome	Myasthénie	À vérifier	Traitement symptomatique	China	À vérifier

Essais cliniques

1

Molécule	Indication / population	Phase	NCT	Titre	Statut
Variables Predicting Reintubation After Thymectomy in Patients With Myasthenia Gravis	Myasthénie	À vérifier	NCT03597373	Variables Predicting Reintubation After Thymectomy in Patients With Myasthenia Gravis	UNKNOWN

Publications

0

Molécule	Indication / population	Titre	Journal	Date
Aucune publication.