Traitements3programmes
Essais1liés
Publications21liées
SourceDBlocale

Traitements

3
MoléculeIndication / populationPhaseObjectifPaysRésultat
Allogeneic umbilical cord mesenchymal stem cellsThis study is to identify the safety and efficacy of repeat IV(Intravenous) and IT(Intrathecal) administrations of UMSC01 in patients with MS. While anti-inflammatory drugs are routinely used for the treatment of MS by inhibiting immune responses, their effects on axon remyelination or neuroregeneration are limited. The combined systemic delivery of UCMSCs via intravenous injection and local administration of the cells by IT was to have safety and therapeutic efficacy for patients with MS. SEP Phase 1/2 Remyélinisation Taiwan À vérifier
Control GroupThe goal of this clinical trial is to determine whether inspiratory muscle training aids in the recovery of respiratory muscle strength and helps prevent further muscle weakness in patients with myasthenia gravis. The primary research questions are: Does inspiratory muscle training enhance respiratory muscle strength recovery? Does the intervention lead to improved lung volumes? Participants underwent daily inspiratory muscle training and aerobic exercise for six consecutive weeks. Myasthénie, SEP Phase 1/2 Remyélinisation Taiwan À vérifier
Allogeneic umbilical cord mesenchymal stem cellsThis study is to identify the safety and efficacy of repeat IV(Intravenous) and IT(Intrathecal) administrations of UMSC01 in patients with MS. While anti-inflammatory drugs are routinely used for the treatment of MS by inhibiting immune responses, their effects on axon remyelination or neuroregeneration are limited. The combined systemic delivery of UCMSCs via intravenous injection and local administration of the cells by IT was to have safety and therapeutic efficacy for patients with MS. SEP Phase 1/2 Remyélinisation Taiwan À vérifier

Essais cliniques

1
MoléculeIndication / populationPhaseNCTTitreStatut
Allogeneic umbilical cord mesenchymal stem cells SEP Phase 1/2 NCT05532943 UMSC01 — Evaluate the Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cells in Patients With Multiple Sclerosis RECRUITING

Publications

21
MoléculeIndication / populationTitreJournalDate
Allogeneic umbilical cord mesenchymal stem cells The Potential Role of Mesenchymal Stem Cell Therapy for Moderate-to-Severe Atopic Dermatitis: A Systematic Review and Meta-Analysis of Human Clinical Trials. Stem cells and development
Allogeneic umbilical cord mesenchymal stem cells Intra-Articular Injection of Human Umbilical Cord-Derived Mesenchymal Stromal Cells Reduces Radiographic Osteoarthritis in an Ovine Model. Cartilage
Allogeneic umbilical cord mesenchymal stem cells Mesenchymal stem cell-derived small extracellular vesicles in spinal cord injury: From molecular repair mechanisms to standardized translational development. Journal of neuroscience methods
Control Group Comparative efficacy of percutaneous vertebroplasty combined with minimally invasive pedicle screw fixation versus percutaneous vertebroplasty alone in the treatment of elderly osteoporotic vertebral compression fractures. The Libyan journal of medicine
Control Group Chinese herbal medicine Xiangsu Hewei Granules in treating non-erosive gastroesophageal reflux disease with liver stomach stagnation heat syndrome: A multicentre, randomized, double-blind, placebo-controlled trial. Journal of ethnopharmacology
Control Group Unveiling the skin-protective material basis of Coreopsis tinctoria Nutt.: Ethnopharmacology-Guided discovery of multi-target enzyme inhibitors using a ligand-fishing approach. Journal of ethnopharmacology
Allogeneic umbilical cord mesenchymal stem cells Allogeneic mesenchymal stromal cells ameliorate lupus nephritis by regulating lipid metabolism via ASGR1. Stem cell research & therapy
Allogeneic umbilical cord mesenchymal stem cells Mesenchymal stem cell therapy as adjunctive treatment in pediatric patients with severe acquired brain injury: a single-center retrospective case series. Frontiers in pediatrics
Control Group Decellularization of Cartilage Xenograft with Supercritical CO. Tissue engineering. Part C, Methods
Control Group Efficacy of emotional working memory training on cognitive emotion regulation and risky decision-making in university students with problematic internet use: a randomised controlled trial. Cognition & emotion
Control Group [Methyl syringate alleviates DSS-induced colitis in mice by suppressing intestinal epithelial cell apoptosis inhibiting the MAPK signaling pathway]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Control Group Mechanical Thrombectomy in Ischemic Stroke With a Medium or Distal Arterial Occlusion: The DISCOUNT Randomized Clinical Trial. JAMA
Control Group The effect of an interactive game played with women of reproductive age with hearing disabilities on menstrual cycle and hygiene perception: a quasi-experimental study. Disability and rehabilitation. Assistive technology
Control Group Does Cognitive Bias Modification for Appraisals Change Symptom-Cognition Relations in PTSD? Preliminary Evidence from Network Analysis in a Randomized Controlled Trial. Clinical psychology & psychotherapy
Control Group Introduction of Nurse-Led Rehabilitation Services for Patients With Stroke After Discharge to Improve Self-Care Management in Bangladesh: Pilot Randomized Controlled Trial. JMIR rehabilitation and assistive technologies
Control Group Mortality in agriculture workers: a case-control study in Italy. Epidemiologia e prevenzione
Control Group The Role of CC10 Combined With CysLTs in Predicting Subsequent Wheezing in RSV-Infected Bronchiolitis. Canadian respiratory journal
Control Group Impact of Pre-operative Single-dose Methylprednisolone on Outcomes After Major Hepatectomy in Adults: A Prospective, Randomised Controlled Trial. Journal of clinical and experimental hepatology
Control Group CD8+ T Cells in Acute Lymphoblastic Leukemia Show a Progenitor-exhausted Phenotype. Iranian journal of allergy, asthma, and immunology
Control Group Evaluating the Effectiveness of Screen-Based Haptic Virtual Reality Simulators in Preclinical Prosthodontic Crown Preparation: Mixed Methods Analysis Study. JMIR formative research
Control Group Efficacy, Safety, and Mechanism of the Qi-Lian-Xiao-Pi Prescription (WW-1) for Chronic Atrophic Gastritis After Helicobacter Pylori Eradication: Protocol for a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. JMIR research protocols