Dokuz Eylul University — Biomedical Watch V2

Traitements9programmes

Essais4liés

Publications8liées

SourceDBlocale

Traitements

9

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Aerobic Exercise in Persons With Multiple Sclerosis With Restless Legs SyndromeIn this studly, the effects of an 12-week aerobic exercise training in persons with multiple sclerosis with restless legs syndrome will be investigated.	SEP	NA	À vérifier	Turkey (Türkiye)	À vérifier
BATHE-Family MedicineThis study evaluates the effect of the BATHE therapeutic interview technique on treatment adherence and blood pressure control in primary care hypertension patients. Hypertension patients aged 18-80 years were randomly assigned to an intervention or control group. The intervention group received the structured BATHE communication technique during clinical visits, while the control group received standard primary care counseling on drug adherence and lifestyle changes. Patients were followed for 6 months (visits at baseline, 3 months, and 6 months). Primary outcomes assessed include treatment adherence scores, drug compliance, and blood pressure levels.	Hypertension	Non applicable	À vérifier	Turkey (Türkiye)	À vérifier
Kinesiophobia Associated With Fatigue in Patients With Multiple Sclerosis.This study aims to investigate the presence of kinesiophobia and the factors associated with kinesiophobia in patients diagnosed with multiple sclerosis. Adult volunteer patients aged 18-65 years with a diagnosis of multiple sclerosis who present to the Physical Medicine and Rehabilitation and Neurology outpatient clinics, meet the inclusion criteria, and provide written informed consent will be enrolled in the study. For each patient, Expanded Disability Status Scale (EDSS) scores, spasticity scores according to the Modified Ashworth Scale (MAS), and the Timed 25-Foot Walk Test will be assessed. In addition, the Functional Ambulation Scale, Visual Analog Scale (VAS) for pain, VAS for sleep, Tampa Scale for Kinesiophobia-Fatigue, International Physical Activity Questionnaire, and the Turkish versions of the Hospital Anxiety and Depression Scale will be completed for each patient.	SEP	À vérifier	Traitement symptomatique	Turkey (Türkiye)	À vérifier
Low Level Laser TherapyTrigger finger, also known as stenosing tenosynovitis, is one of the most common disorders affecting the hand. Its lifetime prevalence is 2-3%. Patients typically present with locking of the affected finger during flexion and painful catching during extension. In mild cases, pain, swelling, and morning stiffness may be present without triggering. In more severe cases, the affected finger may become locked in flexion. Conservative treatment methods, corticosteroid injections, and surgical interventions can be used in the treatment of trigger finger. Conservative treatment options include activity modification, splint immobilization, exercise programs, massage, physical therapy modalities including extracorporeal shock wave therapy and therapeutic ultrasound, and nonsteroidal anti-inflammatory drugs (NSAIDs). Splinting is an inexpensive and effective treatment option for trigger finger. Low-level laser therapy (LLLT) is a treatment modality based on photobiomodulation, which leads to biological changes in living organisms through the interaction of photons with atoms or molecules. LLLT is used to promote wound healing and tissue repair, prevent tissue damage, reduce inflammation and edema, and provide analgesia. Several studies have demonstrated the effectiveness of LLLT in the treatment of various musculoskeletal disorders. This study aims to investigate the effects of adding active LLLT to splint treatment in patients with trigger finger. Patients receiving active LLLT plus splint treatment will be compared with those receiving sham LLLT plus splint treatment in terms of clinical and ultrasonographic outcomes.	Myopathies	Non applicable	Immunomodulation + Traitement symptomatique	Turkey (Türkiye)	À vérifier
Sham Low Level Laser TherapyTrigger finger, also known as stenosing tenosynovitis, is one of the most common disorders affecting the hand. Its lifetime prevalence is 2-3%. Patients typically present with locking of the affected finger during flexion and painful catching during extension. In mild cases, pain, swelling, and morning stiffness may be present without triggering. In more severe cases, the affected finger may become locked in flexion. Conservative treatment methods, corticosteroid injections, and surgical interventions can be used in the treatment of trigger finger. Conservative treatment options include activity modification, splint immobilization, exercise programs, massage, physical therapy modalities including extracorporeal shock wave therapy and therapeutic ultrasound, and nonsteroidal anti-inflammatory drugs (NSAIDs). Splinting is an inexpensive and effective treatment option for trigger finger. Low-level laser therapy (LLLT) is a treatment modality based on photobiomodulation, which leads to biological changes in living organisms through the interaction of photons with atoms or molecules. LLLT is used to promote wound healing and tissue repair, prevent tissue damage, reduce inflammation and edema, and provide analgesia. Several studies have demonstrated the effectiveness of LLLT in the treatment of various musculoskeletal disorders. This study aims to investigate the effects of adding active LLLT to splint treatment in patients with trigger finger. Patients receiving active LLLT plus splint treatment will be compared with those receiving sham LLLT plus splint treatment in terms of clinical and ultrasonographic outcomes.	Myopathies	Non applicable	Immunomodulation + Traitement symptomatique	Turkey (Türkiye)	À vérifier
Aerobic Exercise in Persons With Multiple Sclerosis With Restless Legs SyndromeIn this studly, the effects of an 12-week aerobic exercise training in persons with multiple sclerosis with restless legs syndrome will be investigated.	SEP	NA	À vérifier	Turkey (Türkiye)	À vérifier
BATHE-Family MedicineThis study evaluates the effect of the BATHE therapeutic interview technique on treatment adherence and blood pressure control in primary care hypertension patients. Hypertension patients aged 18-80 years were randomly assigned to an intervention or control group. The intervention group received the structured BATHE communication technique during clinical visits, while the control group received standard primary care counseling on drug adherence and lifestyle changes. Patients were followed for 6 months (visits at baseline, 3 months, and 6 months). Primary outcomes assessed include treatment adherence scores, drug compliance, and blood pressure levels.	Hypertension	Non applicable	À vérifier	Turkey (Türkiye)	À vérifier
Low Level Laser TherapyTrigger finger, also known as stenosing tenosynovitis, is one of the most common disorders affecting the hand. Its lifetime prevalence is 2-3%. Patients typically present with locking of the affected finger during flexion and painful catching during extension. In mild cases, pain, swelling, and morning stiffness may be present without triggering. In more severe cases, the affected finger may become locked in flexion. Conservative treatment methods, corticosteroid injections, and surgical interventions can be used in the treatment of trigger finger. Conservative treatment options include activity modification, splint immobilization, exercise programs, massage, physical therapy modalities including extracorporeal shock wave therapy and therapeutic ultrasound, and nonsteroidal anti-inflammatory drugs (NSAIDs). Splinting is an inexpensive and effective treatment option for trigger finger. Low-level laser therapy (LLLT) is a treatment modality based on photobiomodulation, which leads to biological changes in living organisms through the interaction of photons with atoms or molecules. LLLT is used to promote wound healing and tissue repair, prevent tissue damage, reduce inflammation and edema, and provide analgesia. Several studies have demonstrated the effectiveness of LLLT in the treatment of various musculoskeletal disorders. This study aims to investigate the effects of adding active LLLT to splint treatment in patients with trigger finger. Patients receiving active LLLT plus splint treatment will be compared with those receiving sham LLLT plus splint treatment in terms of clinical and ultrasonographic outcomes.	Myopathies	Non applicable	Immunomodulation + Traitement symptomatique	Turkey (Türkiye)	À vérifier
Kinesiophobia Associated With Fatigue in Patients With Multiple Sclerosis.This study aims to investigate the presence of kinesiophobia and the factors associated with kinesiophobia in patients diagnosed with multiple sclerosis. Adult volunteer patients aged 18-65 years with a diagnosis of multiple sclerosis who present to the Physical Medicine and Rehabilitation and Neurology outpatient clinics, meet the inclusion criteria, and provide written informed consent will be enrolled in the study. For each patient, Expanded Disability Status Scale (EDSS) scores, spasticity scores according to the Modified Ashworth Scale (MAS), and the Timed 25-Foot Walk Test will be assessed. In addition, the Functional Ambulation Scale, Visual Analog Scale (VAS) for pain, VAS for sleep, Tampa Scale for Kinesiophobia-Fatigue, International Physical Activity Questionnaire, and the Turkish versions of the Hospital Anxiety and Depression Scale will be completed for each patient.	SEP	À vérifier	Traitement symptomatique	Turkey (Türkiye)	À vérifier

Essais cliniques

4

Molécule	Indication / population	Phase	NCT	Titre	Statut
Kinesiophobia Associated With Fatigue in Patients With Multiple Sclerosis.	SEP	À vérifier	NCT07803523	Kinesiophobia Associated With Fatigue in Patients With Multiple Sclerosis.	COMPLETED
Low Level Laser Therapy	Myopathies	Non applicable	NCT07753460	Low-Level Laser Therapy in the Treatment of Trigger Finger	RECRUITING
BATHE-Family Medicine	Hypertension	Non applicable	NCT07762456	BATHE-Family Medicine	COMPLETED
Aerobic Exercise in Persons With Multiple Sclerosis With Restless Legs Syndrome	SEP	NA	NCT05402956	Aerobic Exercise in Persons With Multiple Sclerosis With Restless Legs Syndrome	UNKNOWN

Publications

8

Molécule	Indication / population	Titre	Journal	Date
BATHE-Family Medicine		Effects of air pollution on disease activity in patients with rheumatoid arthritis.	Annals of the rheumatic diseases
Aerobic Exercise in Persons With Multiple Sclerosis With Restless Legs Syndrome		Feasibility and efficacy of a physical activity intervention for managing restless legs syndrome in multiple sclerosis: Results of a pilot randomized controlled trial.	Multiple sclerosis and related disorders
Sham Low Level Laser Therapy		Acute physiological responses to combined blood flow restriction and low-level laser.	European journal of applied physiology
Sham Low Level Laser Therapy		Photobiomodulation in the management of oral mucositis for adult head and neck cancer patients receiving irradiation: the LiTEFORM RCT.	Health technology assessment (Winchester, England)
Low Level Laser Therapy		Efficacy of 810 nm low-level laser therapy on muscle regeneration after bupivacaine-induced myonecrosis in a rabbit model.	Lasers in medical science
Low Level Laser Therapy		Bibliometric analysis in the field of photobiomodulation in the last two decades: research trends and evolution of hot topics.	Photodiagnosis and photodynamic therapy
Aerobic Exercise in Persons With Multiple Sclerosis With Restless Legs Syndrome		Does physical activity timing differentially correlate with symptoms of restless legs syndrome in adults with multiple sclerosis?	Sleep medicine
Aerobic Exercise in Persons With Multiple Sclerosis With Restless Legs Syndrome		Effect of exergaming in people with restless legs syndrome with multiple sclerosis: A single-blind randomized controlled trial.	Multiple sclerosis and related disorders