Traitements4programmes
Essais2liés
Publications6liées
SourceDBlocale

Traitements

4
MoléculeIndication / populationPhaseObjectifPaysRésultat
LenzumestrocelALSUMMIT is a double-blind, randomized, placebo-controlled, multi-center, parallel, phase III clinical trial to evaluate and confirm the efficacy and long-term safety of repeated Lenzumestrocel (Neuronata-R® inj.) treatment. Sclérose latérale amyotrophique Phase 3 À vérifier South Korea À vérifier
RiluzoleDescription non affichée : incohérence de maladie détectée. Consultez l’essai clinique officiel associé. Parkinson, Sclérose latérale amyotrophique Phase 3 À vérifier South Korea À vérifier
RiluzoleThe purpose of the assay is to assess the safety and the efficacy of TRO19622 330 mg QD as add-on therapy to riluzole 50 mg bid in the treatment of patients suffering from ALS, as compared to placebo, assessed by the 18-month survival rate. Parkinson Phase 3 Neuroprotection United Kingdom À vérifier
LenzumestrocelALSUMMIT is a double-blind, randomized, placebo-controlled, multi-center, parallel, phase III clinical trial to evaluate and confirm the efficacy and long-term safety of repeated Lenzumestrocel (Neuronata-R® inj.) treatment. Sclérose latérale amyotrophique Phase 3 À vérifier South Korea À vérifier

Essais cliniques

2
MoléculeIndication / populationPhaseNCTTitreStatut
Lenzumestrocel Sclérose latérale amyotrophique Phase 3 NCT04745299 ALSummit — Evaluation the Efficacy and Safety of Mutiple Lenzumestrocel (Neuronata-R® Inj.) Treatment in Patients With ALS COMPLETED
Riluzole Parkinson Phase 3 NCT00211224 Neuroprotection and Natural History in Parkinson's Plus Syndromes (NNIPPS) TERMINATED

Publications

6
MoléculeIndication / populationTitreJournalDate
Lenzumestrocel Efficacy and safety of Lenzumestrocel (Neuronata-R® inj.) in patients with amyotrophic lateral sclerosis (ALSUMMIT study): study protocol for a multicentre, randomized, double-blind, parallel-group, sham procedure-controlled, phase III trial. Trials
Lenzumestrocel Long-term survival benefits of intrathecal autologous bone marrow-derived mesenchymal stem cells (Neuronata-R®: lenzumestrocel) treatment in ALS: Propensity-score-matched control, surveillance study. Frontiers in aging neuroscience
Riluzole Prescribing and monitoring of riluzole in amyotrophic lateral sclerosis: a retrospective cohort study from Health New Zealand - Te Whatu Ora Waitaha Canterbury. The New Zealand medical journal
Riluzole Introducing Borsantrazole: A Trifunctional Boron-Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice. Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Riluzole Huoling Shengji granule in amyotrophic lateral sclerosis: A multicenter, randomized, double-blind, riluzole-controlled trial. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Riluzole Nose-to-brain delivery of riluzole-loaded nanoemulsion in a controlled cortical impact-induced traumatic brain injury: Insights fromIn vitro,Ex vivo, andIn vivostudies. Colloids and surfaces. B, Biointerfaces