Cooperative International Neuromuscular Research Group — Biomedical Watch V2

Traitements3programmes

Essais1liés

Publications18liées

SourceDBlocale

Traitements

3

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Creatine MonohydrateThis study will help to determine the effectiveness of glutamine and creatine as a possible therapy for DMD. Boys with DMD who are enrolled in this trial will be randomly chosen to receive creatine monohydrate or glutamine or an inactive placebo orally for six months. Once a month during the six-month treatment period, the study participants will have their muscle strength evaluated using manual and computerized testing methods. This study will be conducted at several CINRG Centers throughout the U.S., Belgium, Israel and Puerto Rico. This study is supported by the Muscular Dystrophy Association.	Myopathies	Phase 2	À vérifier	United States	À vérifier
GlutamineThis study will help to determine the effectiveness of glutamine and creatine as a possible therapy for DMD. Boys with DMD who are enrolled in this trial will be randomly chosen to receive creatine monohydrate or glutamine or an inactive placebo orally for six months. Once a month during the six-month treatment period, the study participants will have their muscle strength evaluated using manual and computerized testing methods. This study will be conducted at several CINRG Centers throughout the U.S., Belgium, Israel and Puerto Rico. This study is supported by the Muscular Dystrophy Association.	Myopathies	Phase 2	À vérifier	United States	À vérifier
Creatine MonohydrateThis study will help to determine the effectiveness of glutamine and creatine as a possible therapy for DMD. Boys with DMD who are enrolled in this trial will be randomly chosen to receive creatine monohydrate or glutamine or an inactive placebo orally for six months. Once a month during the six-month treatment period, the study participants will have their muscle strength evaluated using manual and computerized testing methods. This study will be conducted at several CINRG Centers throughout the U.S., Belgium, Israel and Puerto Rico. This study is supported by the Muscular Dystrophy Association.	Myopathies	Phase 2	À vérifier	United States	À vérifier

Essais cliniques

1

Molécule	Indication / population	Phase	NCT	Titre	Statut
Creatine Monohydrate	Myopathies	Phase 2	NCT00016653	Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy	COMPLETED

Publications

18

Molécule	Indication / population	Titre	Journal	Date
Glutamine		Transglutaminase 2 regulates innate immunity: mechanisms and therapeutic implications.	Oncoimmunology
Glutamine		Real-time NMR analysis of glutamine metabolism for screening anti-cancer agents in living cells.	Magnetic resonance letters
Creatine Monohydrate		The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications.	Journal of the International Society of Sports Nutrition
Creatine Monohydrate		Creatine monohydrate for lean mass, strength, and bone density in postmenopausal women: a systematic review and meta-analysis.	Journal of the International Society of Sports Nutrition
Glutamine		Grape-Derived Exosome-like Nanoparticles Ameliorate Prediabetes in Mice via Amino Acid Metabolic Reprogramming.	International journal of molecular sciences
Glutamine		Species Dynamics and Gene Expression in Algal Polycultures Under Mixotrophic Cultivation in Outdoor Pilot-Scale Nordic Conditions.	Biotechnology and bioengineering
Creatine Monohydrate		Creatine monohydrate supplementation for recovery from muscle disuse: Timing matters.	Sports medicine and health science
Creatine Monohydrate		Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults.	Journal of the International Society of Sports Nutrition
Glutamine		Identification and Key Amino Acid Analysis of Epitopes of Pin y 2, a Novel Allergen from .	Journal of agricultural and food chemistry
Glutamine		Glycosylation penetrance of N-X-S/T sequons in antibody variable domains: a structural survey of 19,265 human antibody structures reassessing the histidine/glutamine suppression hypothesis.	mAbs
Glutamine		Palometa fish (Serrasalmus maculatus) meat: Amino acids profile by gas chromatography-mass spectrometry, pulping and application in salty cookies.	Anais da Academia Brasileira de Ciencias
Creatine Monohydrate		Examining the feasibility and preliminary effects of resistance exercise training and creatine supplementation in individuals treated for colorectal cancer.	PloS one
Glutamine		[Effect of electroacupuncture on chronic pain in patients with knee osteoarthritis and its influence on central sensitization].	Zhongguo zhen jiu = Chinese acupuncture & moxibustion
Glutamine		Insulin Regulates CD36-Dependent Fatty Acid Uptake but Not Mitochondrial Oxidation in Sertoli Cells.	Andrology
Creatine Monohydrate		Does creatine supplementation improve strength and power in physically active individuals on a vegan diet? a randomized, triple-blind, placebo-controlled trial.	European journal of applied physiology
Creatine Monohydrate		Exercise-Induced Rhabdomyolysis With Markedly Elevated Creatine Kinase and Preserved Renal Function.	Case reports in nephrology
Glutamine		Genome-wide characterization of the Bcl-2-associated athanogene (BAG) gene family and functional analysis of ZmBAG14 under drought stress in maize.	Plant physiology and biochemistry : PPB
Glutamine		How do media compositions, pretreatments, and genotypes affect haploidization in sweet watermelon (Citrullus lanatus var. lanatus) ovary culture?	BMC plant biology