Comenius University — Biomedical Watch V2

Traitements5programmes

Essais2liés

Publications0liées

SourceDBlocale

Traitements

5

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Active Intermittent Theta-Burst Stimulation (iTBS)Spasticity and neuropathic pain are frequent and disabling symptoms of multiple sclerosis. Intermittent theta-burst stimulation (iTBS) is a non-invasive neuromodulation technique that may modulate cortical and corticospinal excitability and thereby improve motor symptoms and pain. This randomized, parallel-group, sham-controlled, assessor-blinded study will evaluate the clinical efficacy of active iTBS compared with sham stimulation in adults with multiple sclerosis and clinically significant lower-limb spasticity and pain. Participants will receive five stimulation sessions over one week. Spasticity, pain, patient-reported outcomes, and the electrophysiological H/M ratio will be assessed at baseline and at Weeks 2 and 4 after the intervention.	SEP	Non applicable	Traitement symptomatique	Slovakia	À vérifier
Sham Intermittent Theta-Burst StimulationSpasticity and neuropathic pain are frequent and disabling symptoms of multiple sclerosis. Intermittent theta-burst stimulation (iTBS) is a non-invasive neuromodulation technique that may modulate cortical and corticospinal excitability and thereby improve motor symptoms and pain. This randomized, parallel-group, sham-controlled, assessor-blinded study will evaluate the clinical efficacy of active iTBS compared with sham stimulation in adults with multiple sclerosis and clinically significant lower-limb spasticity and pain. Participants will receive five stimulation sessions over one week. Spasticity, pain, patient-reported outcomes, and the electrophysiological H/M ratio will be assessed at baseline and at Weeks 2 and 4 after the intervention.	SEP	Non applicable	Traitement symptomatique	Slovakia	À vérifier
SPPA — Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs IntakeBy conducting the SPPA trial we try to find out, whether personalized Short Message Service (SMS) reminders of blood pressure-lowering medication can effectively increase patients' adherence to blood pressure-lowering medication. Additionally, we also evaluate their effect on patients' systolic blood pressure control.	Hypertension	NA	À vérifier	Slovakia	À vérifier
SPPA — Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs IntakeBy conducting the SPPA trial we try to find out, whether personalized Short Message Service (SMS) reminders of blood pressure-lowering medication can effectively increase patients' adherence to blood pressure-lowering medication. Additionally, we also evaluate their effect on patients' systolic blood pressure control.	Hypertension	NA	À vérifier	Slovakia	À vérifier
Active Intermittent Theta-Burst Stimulation (iTBS)Spasticity and neuropathic pain are frequent and disabling symptoms of multiple sclerosis. Intermittent theta-burst stimulation (iTBS) is a non-invasive neuromodulation technique that may modulate cortical and corticospinal excitability and thereby improve motor symptoms and pain. This randomized, parallel-group, sham-controlled, assessor-blinded study will evaluate the clinical efficacy of active iTBS compared with sham stimulation in adults with multiple sclerosis and clinically significant lower-limb spasticity and pain. Participants will receive five stimulation sessions over one week. Spasticity, pain, patient-reported outcomes, and the electrophysiological H/M ratio will be assessed at baseline and at Weeks 2 and 4 after the intervention.	SEP	Non applicable	Traitement symptomatique	Slovakia	À vérifier

Essais cliniques

2

Molécule	Indication / population	Phase	NCT	Titre	Statut
Active Intermittent Theta-Burst Stimulation (iTBS)	SEP	Non applicable	NCT07786506	TMS-SPASMS — Intermittent Theta-Burst Stimulation for Lower-Limb Spasticity and Pain in Multiple Sclerosis	NOT_YET_RECRUITING
SPPA — Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs Intake	Hypertension	NA	NCT03105687	SPPA — Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs Intake	COMPLETED

Publications

0

Molécule	Indication / population	Titre	Journal	Date
Aucune publication.