Baylor College of Medicine — Biomedical Watch V2

Traitements4programmes

Essais2liés

Publications0liées

SourceDBlocale

Traitements

4

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Glutathione, Brain Metabolism and Inflammation in Alzheimer's DiseaseAlzheimer's disease (AD) is associated with significant, progressive cognitive decline. Key defects in mitochondrial fuel metabolism insulin resistance, inflammation and decreased brain glucose uptake are linked to AD. This trial will investigate the effects of supplementing glycine and N-acetylcysteine vs. alanine as placebo on these defects in AD, and examine the effects on cognition.	Alzheimer	Phase 1	Remyélinisation indirecte / réparation + Immunomodulation	United States	À vérifier
Speedboat™ UltraslimBoth Baylor St Luke's Medical Center and Mayo Scottsdale are considered endoscopic submucosal dissection (ESD) centers of excellence. The investigators at Baylor College of Medicine have previously reported our Esophageal ESD experience using the monopolar current knife. Moreover, the research team have previously reported on the clinical efficacy of the bipolar RFA knife during per-oral endoscopic myotomy (POEM) and colonic ESD. The goal of our study is to prospectively evaluate the efficacy, safety and feasibility of Esophageal ESD using a novel Bipolar-Current ESD device.	Cancer	À vérifier	À vérifier	United States	À vérifier
Speedboat™ UltraslimBoth Baylor St Luke's Medical Center and Mayo Scottsdale are considered endoscopic submucosal dissection (ESD) centers of excellence. The investigators at Baylor College of Medicine have previously reported our Esophageal ESD experience using the monopolar current knife. Moreover, the research team have previously reported on the clinical efficacy of the bipolar RFA knife during per-oral endoscopic myotomy (POEM) and colonic ESD. The goal of our study is to prospectively evaluate the efficacy, safety and feasibility of Esophageal ESD using a novel Bipolar-Current ESD device.	Cancer	À vérifier	À vérifier	United States	À vérifier
Glutathione, Brain Metabolism and Inflammation in Alzheimer's DiseaseAlzheimer's disease (AD) is associated with significant, progressive cognitive decline. Key defects in mitochondrial fuel metabolism insulin resistance, inflammation and decreased brain glucose uptake are linked to AD. This trial will investigate the effects of supplementing glycine and N-acetylcysteine vs. alanine as placebo on these defects in AD, and examine the effects on cognition.	Alzheimer	Phase 1	Remyélinisation indirecte / réparation + Immunomodulation	United States	À vérifier

Essais cliniques

2

Molécule	Indication / population	Phase	NCT	Titre	Statut
Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease	Alzheimer	Phase 1	NCT04740580	Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease	ACTIVE_NOT_RECRUITING
Speedboat™ Ultraslim	Cancer	À vérifier	NCT06476678	Novel Bipolar Radiofrequency Ablation Knife in Esophageal Lesions	RECRUITING

Publications

0

Molécule	Indication / population	Titre	Journal	Date
Aucune publication.