Traitements6programmes
Essais2liés
Publications5liées
SourceDBlocale

Traitements

6
MoléculeIndication / populationPhaseObjectifPaysRésultat
AritinerceptThis clinical study will enroll patients with generalized myasthenia gravis (gMG). The goal of this clinical study is to assess the safety, tolerability, effectiveness, pharmacokinetics (how the body processes the drug) and pharmacodynamics (how the drug affects the body) of aritinercept. Myasthénie Phase 1/2 À vérifier United States À vérifier
belimumab, obinutuzumab or anifrolumabThe goal of this clinical study is to assess the efficacy and safety of LUPKYNIS® in combination with belimumab, obinutuzumab or anifrolumab at inducing rapid renal response in patients with lupus nephritis (LN). Lupus Phase 4 À vérifier United States À vérifier
LUPKYNISThe goal of this clinical study is to assess the efficacy and safety of LUPKYNIS® in combination with belimumab, obinutuzumab or anifrolumab at inducing rapid renal response in patients with lupus nephritis (LN). Lupus Phase 4 À vérifier United States À vérifier
mycophenolic acid analog (MPAA)The goal of this clinical study is to assess the efficacy and safety of LUPKYNIS® in combination with belimumab, obinutuzumab or anifrolumab at inducing rapid renal response in patients with lupus nephritis (LN). Lupus Phase 4 À vérifier United States À vérifier
AritinerceptThis clinical study will enroll patients with generalized myasthenia gravis (gMG). The goal of this clinical study is to assess the safety, tolerability, effectiveness, pharmacokinetics (how the body processes the drug) and pharmacodynamics (how the drug affects the body) of aritinercept. Myasthénie Phase 1/2 À vérifier United States À vérifier
LUPKYNISThe goal of this clinical study is to assess the efficacy and safety of LUPKYNIS® in combination with belimumab, obinutuzumab or anifrolumab at inducing rapid renal response in patients with lupus nephritis (LN). Lupus Phase 4 À vérifier United States À vérifier

Essais cliniques

2
MoléculeIndication / populationPhaseNCTTitreStatut
LUPKYNIS Lupus Phase 4 NCT07611214 PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis RECRUITING
Aritinercept Myasthénie Phase 1/2 NCT07596901 Study of Aritinercept in Patients With Generalized Myasthenia Gravis RECRUITING

Publications

5
MoléculeIndication / populationTitreJournalDate
mycophenolic acid analog (MPAA) Corticosteroids and mycophenolic acid analogues in immunoglobulin A nephropathy with progressive decline in kidney function. Clinical kidney journal
LUPKYNIS Voclosporin: A Novel Calcineurin Inhibitor for the Treatment of Lupus Nephritis. The Annals of pharmacotherapy
mycophenolic acid analog (MPAA) Lupus nephritis randomised controlled trials: evidence gaps and under-represented groups. Lupus science & medicine
mycophenolic acid analog (MPAA) Systematic Review and Network Meta-Analysis of Initial Treatments for Lupus Nephritis. Kidney international reports
LUPKYNIS Obinutuzumab (Gazyva) for lupus nephritis. The Medical letter on drugs and therapeutics