Clinical trials
Recherche d’études cliniques
Recherchez uniquement dans les études cliniques enregistrées dans Biomedical Watch.
Études cliniques 211
| Étude / NCT ⇅ | Molécule ⇅ | Maladie ⇅ | Phase ⇅ | Statut ⇅ | Résultat ⇅ | Sponsor ⇅ | Pays / centres ⇅ | Période ⇅ | Détail |
|---|---|---|---|---|---|---|---|---|---|
| NCT05297487 RELAX SLA — Evaluation of the Early Use of the Pressure Relaxer in the … |
early use of intermittent positiv… | Sclérose latérale amyotrophique | Non applicable | WITHDRAWN | En attente / non publié | Centre Hospitalier Universitaire … | Non communiqué | 2025-07-01 → 2028-07-01 | Ouvrir |
| NCT06834269 Transcranial Static Magnetic Stimulation (tSMS) and Potential Theranost… |
Transcranial magnetic stimulation… | Sclérose latérale amyotrophique | Non applicable | ACTIVE_NOT_RECRUITING | En attente / non publié | Campus Bio-Medico University | Italy · Fondazione Policlinico Campus Bio-Medico, Rom… | 2024-12-02 → 2027-12-31 | Ouvrir |
| NCT07369076 A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic L… |
NB-4746 High dose | Sclérose latérale amyotrophique | Phase 1/2 | RECRUITING | En attente / non publié | Nura Bio | Australia, Canada, Netherlands, Poland · Calvery Heal… | 2026-03-04 → 2028-02 | Ouvrir |
| NCT07818772 7T Imaging Pilot-study in Patients With Motor Neuron Disease to Find No… |
MRI | Sclérose latérale amyotrophique | À vérifier | RECRUITING | En attente / non publié | National Institute of Neurologica… | United Kingdom · ICE Building, Glasgow, United Kingdom | 2026-04-13 → 2026-11-30 | Ouvrir |
| NCT06363357 The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Func… |
Shoulder orthosis | Sclérose latérale amyotrophique | Non applicable | COMPLETED | En attente / non publié | Seoul National University Hospital | South Korea · Seoul National University Hospital, Seo… | 2024-04-20 → 2025-12-31 | Ouvrir |
| NCT06551649 CONTRASTOME — Human Amniotic Mesenchymal Cell Secretome for Neurodegene… |
CONTRASTOME — Human Amniotic Mese… | Sclérose latérale amyotrophique | Non applicable | ACTIVE_NOT_RECRUITING | En attente / non publié | Fondazione Policlinico Universita… | Italy · Fondazione Policlinico Universitario A. Gemel… | 2025-01-17 → 2027-02-28 | Ouvrir |
| NCT07589764 ROAR HMB — Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IG… |
β-hydroxy-β-methylbutyrate (HMB) | Sclérose latérale amyotrophique | Phase 1 | NOT_YET_RECRUITING | En attente / non publié | Duke University | United States · Duke University Medical Center, Durha… | 2026-10-01 → 2027-10-01 | Ouvrir |
| NCT05683860 Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-as… |
WVE-004 10 mg Q12W | Sclérose latérale amyotrophique | Phase 1/2 | TERMINATED | En attente / non publié | Wave Life Sciences USA, Inc. | Netherlands, United Kingdom · Erasmus MC, Rotterdam, … | 2022-12-14 → 2023-06-27 | Ouvrir |
| NCT07813858 CO-ALSII — Colchicine Effect on Amyotrophic Lateral Sclerosis Patients |
Colchicine 0.5 MG Oral Tablet | Sclérose latérale amyotrophique | Phase 2 | NOT_YET_RECRUITING | En attente / non publié | Azienda Ospedaliero-Universitaria… | Italy · Centro Clinico NeMO, Milan, Italy | CENTRO SL… | 2026-10 → 2028-12 | Ouvrir |
| NCT06649955 CALM — Controlling Amyotrophic Lateral Sclerosis Motor Neuron Excitabil… |
Multi-site direct current stimula… | Sclérose latérale amyotrophique | Non applicable | RECRUITING | En attente / non publié | PathMaker Neurosystems Inc. | United States · Beth Israel Deaconess Medical Center,… | 2025-02-10 → 2027-02 | Ouvrir |
| NCT03766321 FETR-ALS — Fecal Microbiota Transplantation Effect on Amyotrophic Later… |
Fecal microbiota transplantation | Sclérose latérale amyotrophique | Non applicable | COMPLETED | En attente / non publié | Azienda Ospedaliero-Universitaria… | Italy · Azienda Ospedaliero Universitaria Di Modena, … | 2020-07-01 → 2025-06-01 | Ouvrir |
| NCT04667013 A Multiple Dose Study to Investigate Safety, Tolerability and Pharmacok… |
A Multiple Dose Study to Investig… | Sclérose latérale amyotrophique | Phase 1 | NOT_YET_RECRUITING | En attente / non publié | Guangzhou Magpie Pharmaceuticals … | Non communiqué | 2028-09-01 → 2029-08-30 | Ouvrir |
| NCT03651349 To Determine the Maximum Tolerated Dose (MTD) of HK-001 in Healthy Volu… |
HK-001 | Sclérose latérale amyotrophique | Phase 1 | ACTIVE_NOT_RECRUITING | En attente / non publié | Everfront Biotech Co., Ltd. | Taiwan · Hualien Tzu Chi Hospital, Buddhist Tzu Chi M… | 2021-02-01 → 2028-06-30 | Ouvrir |
| NCT07674667 FUNCtion ALS: Aiming to Restore UNC13A Function in People Living With A… |
TRCN-1023 | Sclérose latérale amyotrophique | Phase 1/2 | RECRUITING | En attente / non publié | Trace Neuroscience, Inc. | Germany, Netherlands, United Kingdom · TUM Klinikum R… | 2026-08-20 → 2027-09 | Ouvrir |
| NCT07325591 Efficacy and Safety of Tazbentetol in ALS Participants |
Tazbentetol | Sclérose latérale amyotrophique | Phase 2/3 | NOT_YET_RECRUITING | En attente / non publié | Spinogenix | Non communiqué | 2026-10-01 → 2028-03-01 | Ouvrir |
| NCT07796776 TDP-signatures — The Aim of the Study is to Characterize Patients Exhib… |
TDP-signatures — The Aim of the S… | Sclérose latérale amyotrophique | À vérifier | ACTIVE_NOT_RECRUITING | En attente / non publié | IRCCS San Raffaele | Italy · IRCCS Ospedale San Raffaele, Milan, Italy | 2026-07-01 → 2030-07-01 | Ouvrir |
| NCT04244630 Mitochondrial Capacity Boost in ALS (MICABO-ALS) Trial |
Antioxidants | Sclérose latérale amyotrophique | Phase 2 | ACTIVE_NOT_RECRUITING | En attente / non publié | Dallas VA Medical Center | United States · VA North Texas Health Care System, Da… | 2023-11-02 → 2026-12 | Ouvrir |
| NCT07798700 BRAIN — Biofluid Research on Age-Related or Inherited Neurodegeneration |
BRAIN — Biofluid Research on Age-… | Sclérose latérale amyotrophique | À vérifier | RECRUITING | En attente / non publié | University of Pennsylvania | United States · University of Pennsylvania, Philadelp… | 2025-12-12 → 2070-01-01 | Ouvrir |
| NCT06596746 Neurodegenerative Diseases Progression Markers (MARKERS-NDD) |
Neurodegenerative Diseases Progre… | Sclérose latérale amyotrophique | À vérifier | RECRUITING | En attente / non publié | Casa di Cura San Raffaele Cassino | Italy · San Raffaele Cassino, Cassino, Italy | 2024-09-09 → 2034-09-09 | Ouvrir |
| NCT07023835 UNITE-ALS — Usnoflast Neuromuscular Investigation for Treatment Efficac… |
50 mg Usnoflast | Sclérose latérale amyotrophique | Phase 2 | RECRUITING | En attente / non publié | Zydus Therapeutics Inc. | United States, Australia, Belgium, Canada, France, Ge… | 2025-09-17 → 2028-10 | Ouvrir |
| NCT06743776 SEANOBI-ALS — Scalable Expanded Access With Analysis of Neurofilament a… |
MN-166 | Sclérose latérale amyotrophique | À vérifier | NO_LONGER_AVAILABLE | En attente / non publié | Mayo Clinic | United States · Augusta University, Augusta, United S… | Non communiqué | Ouvrir |
| NCT06824961 LUCASVP — Does Increasing the Compression Pause From 3 to 5 Seconds in … |
LUCASVP — Does Increasing the Com… | Sclérose latérale amyotrophique | Non applicable | RECRUITING | En attente / non publié | Amsterdam UMC, location VUmc | Netherlands · Ambulance Amsterdam, Amsterdam, Netherl… | 2026-01-15 → 2027-07 | Ouvrir |
| NCT05602142 Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglia… |
[11C]CPPC PET ligand | Sclérose latérale amyotrophique | Phase 1/2 | NOT_YET_RECRUITING | En attente / non publié | Johns Hopkins University | Non communiqué | 2026-11 → 2027-07 | Ouvrir |
| NCT07224269 TZ-ALS — Effect of Terazosin on ATP Levels in People With Amyotrophic L… |
Terazosine | Sclérose latérale amyotrophique | Phase 1 | RECRUITING | En attente / non publié | University of Iowa | United States · University of Iowa Health Care, Iowa … | 2026-08-12 → 2027-10-31 | Ouvrir |
| NCT04220021 Safety and Therapeutic Potential of the FDA-approved Drug Metformin for… |
Metformin | Sclérose latérale amyotrophique | Phase 2 | ACTIVE_NOT_RECRUITING | En attente / non publié | University of Florida | United States · UF Health at the University of Florid… | 2020-01-10 → 2027-08-31 | Ouvrir |